Optimization of an HTRF Assay for the Detection of Soluble Mutant Huntingtin in Human Buffy Coats: A Potential Biomarker in Blood for Huntington Disease

por Moscovitch-Lopatin, Miriam, Weiss, Andreas, Rosas, Herminia Diana, Ritch, James, Doros, Gheorghe, Kegel, Kimberly B., Difiglia, Marian, Kuhn, Rainer, Bilbe, Graeme, Paganetti, Paolo, Hersch, Steven
Publicado 2010

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity

por Yao, Yuwei, Cui, Xiaotian, Al-Ramahi, Ismael, Sun, Xiaoli, Li, Bo, Hou, Jiapeng, Difiglia, Marian, Palacino, James, Wu, Zhi-Ying, Ma, Lixiang, Botas, Juan, Lu, Boxun
Publicado 2015

Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain

por Alterman, Julia F, Hall, Lauren M, Coles, Andrew H, Hassler, Matthew R, Didiot, Marie-Cecile, Chase, Kathryn, Abraham, Jasmin, Sottosanti, Emily, Johnson, Emily, Sapp, Ellen, Osborn, Maire F, Difiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicado 2015

Behavioral deficits, early gliosis, dysmyelination and synaptic dysfunction in a mouse model of mucolipidosis IV

por Grishchuk, Yulia, Sri, Sarmi, Rudinskiy, Nikita, Ma, Weiyuan, Stember, Katherine G., Cottle, Matthew W., Sapp, Ellen, Difiglia, Marian, Muzikansky, Alona, Betensky, Rebecca A., Wong, Andrew M. S., Bacskai, Brian J., Hyman, Bradley T., Kelleher, Raymond J., Cooper, Jonathan D., Slaugenhaupt, Susan A.
Publicado 2014

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

por O’Rourke, Jacqueline Gire, Gareau, Jaclyn R., Ochaba, Joseph, Song, Wan, Raskó, Tamás, Reverter, David, Lee, John, Monteys, Alex Mas, Pallos, Judit, Mee, Lisa, Vashishtha, Malini, Apostol, Barbara L., Nicholson, Thomas Peter, Illes, Katalin, Zhu, Ya-Zhen, Dasso, Mary, Bates, Gillian P., Difiglia, Marian, Davidson, Beverly, Wanker, Erich E., Marsh, J. Lawrence, Lima, Christopher D., Steffan, Joan S., Thompson, Leslie M.
Publicado 2013