Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs

por Ferreira, Guilherme S., Dijkstra, Francis M., Veening-Griffioen, Désirée H., Boon, Wouter P. C., Schellekens, Huub, Moors, Ellen H. M., van Meer, Peter J. K., Stuurman, Frederik E., van Gerven, Joop M. A.
Publicado 2023

Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers

por Dijkstra, Francis M., Zuiker, Rob G. J. A., Siebenga, Pieter S., Leigh‐Pemberton, Richard A., Sun, Lei, Manthis, Joan D., de Kam, Marieke L., Lin, Richard, von Moltke, Lisa L., Rezendes, David, van Gerven, Joop M. A.
Publicado 2022

The effects of intranasal esketamine on on-road driving performance in patients with major depressive disorder or persistent depressive disorder

por Dijkstra, Francis M, van de Loo, Aurora JAE, Abdulahad, Smedra, Bosma, Else R, Hartog, Mitch, Huls, Hendrikje, Kuijper, Dianne C, de Vries, Esther, Solanki, Bhavna, Singh, Jaskaran, Aluisio, Leah, Zannikos, Peter, Stuurman, Frederik E, Jacobs, Gabriël E, Verster, Joris C
Publicado 2022

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

por O’Donnell, Patricio, Dijkstra, Francis M., Damar, Ugur, Quanhong, Lei, de Goede, Annika A., Xu, Lin, Pascual-Leone, Andres, Buhl, Derek L., Zuiker, Rob, Ruijs, Titia Q., Heuberger, Jules A. A. C., MacMullin, Paul, Lubell, Martin, Asgharnejad, Mahnaz, Murthy, Venkatesha, Rotenberg, Alexander, Jacobs, Gabriel E., Rosen, Laura
Publicado 2021