Combined ATR and DNA-PK Inhibition Radiosensitizes Tumor Cells Independently of Their p53 Status

por Hafsi, Hind, Dillon, Magnus T., Barker, Holly E., Kyula, Joan N., Schick, Ulrike, Paget, James T., Smith, Henry G., Pedersen, Malin, McLaughlin, Martin, Harrington, Kevin J.
Publicado 2018

The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

por McLaughlin, Martin, Pedersen, Malin, Roulstone, Victoria, Bergerhoff, Katharina F., Smith, Henry G., Whittock, Harriet, Kyula, Joan N., Dillon, Magnus T., Pandha, Hardev S., Vile, Richard, Melcher, Alan A., Harrington, Kevin J.
Publicado 2020

HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation

por McLaughlin, Martin, Barker, Holly E., Khan, Aadil A., Pedersen, Malin, Dillon, Magnus, Mansfield, David C., Patel, Radhika, Kyula, Joan N., Bhide, Shreerang A., Newbold, Kate L., Nutting, Christopher M., Harrington, Kevin J.
Publicado 2017

Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade

por Patin, Emmanuel C, Dillon, Magnus T, Nenclares, Pablo, Grove, Lorna, Soliman, Heba, Leslie, Isla, Northcote, Davina, Bozhanova, Galabina, Crespo-Rodriguez, Eva, Baldock, Holly, Whittock, Harriet, Baker, Gabriella, Kyula, Joan, Guevara, Jeane, Melcher, Alan A, Harper, James, Ghadially, Hormas, Smith, Simon, Pedersen, Malin, McLaughlin, Martin, Harrington, Kevin J
Publicado 2022

Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer

por Wilkins, Anna, Fontana, Elisa, Nyamundanda, Gift, Ragulan, Chanthirika, Patil, Yatish, Mansfield, David, Kingston, Jennifer, Errington-Mais, Fiona, Bottomley, Daniel, von Loga, Katharina, Bye, Hannah, Carter, Paul, Tinkler-Hundal, Emma, Noshirwani, Arish, Downs, Jessica, Dillon, Magnus, Demaria, Sandra, Sebag-Montefiore, David, Harrington, Kevin, West, Nick, Melcher, Alan, Sadanandam, Anguraj
Publicado 2021

Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development

por Barber, Paul R, Mustapha, Rami, Flores-Borja, Fabian, Alfano, Giovanna, Ng, Kenrick, Weitsman, Gregory, Dolcetti, Luigi, Suwaidan, Ali Abdulnabi, Wong, Felix, Vicencio, Jose M, Galazi, Myria, Opzoomer, James W, Arnold, James N, Thavaraj, Selvam, Kordasti, Shahram, Doyle, Jana, Greenberg, Jon, Dillon, Magnus T, Harrington, Kevin J, Forster, Martin, Coolen, Anthony CC, Ng, Tony
Publicado 2022