NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis

por Shersher, Elena, Lahiry, Mohini, Alvarez-Trotta, Annamil, Diluvio, Giulia, Robbins, David J., Shiekhattar, Ramin, Capobianco, Anthony J.
Publicado 2021

A novel chemical attack on Notch-mediated transcription by targeting the NACK ATPase

por Diluvio, Giulia, Kelley, Tanya T., Lahiry, Mohini, Alvarez-Trotta, Annamil, Kolb, Ellen M., Shersher, Elena, Astudillo, Luisana, Kovall, Rhett A., Schürer, Stephan C., Capobianco, Anthony J.
Publicado 2023

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest

por Diluvio, Giulia, Del Gaudio, Francesca, Giuli, Maria Valeria, Franciosa, Giulia, Giuliani, Eugenia, Palermo, Rocco, Besharat, Zein Mersini, Pignataro, Maria Gemma, Vacca, Alessandra, d’Amati, Giulia, Maroder, Marella, Talora, Claudio, Capalbo, Carlo, Bellavia, Diana, Checquolo, Saula
Publicado 2018

Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response

por Giuli, Maria Valeria, Diluvio, Giulia, Giuliani, Eugenia, Franciosa, Giulia, Di Magno, Laura, Pignataro, Maria Gemma, Tottone, Luca, Nicoletti, Carmine, Besharat, Zein Mersini, Peruzzi, Giovanna, Pelullo, Maria, Palermo, Rocco, Canettieri, Gianluca, Talora, Claudio, d’Amati, Giulia, Bellavia, Diana, Screpanti, Isabella, Checquolo, Saula
Publicado 2020