Editorial: Mechanisms and strategies of unconventional antibody diversification for greater immune adaptability

por Dimitrov, Jordan D., Mwangi, Waithaka, Zhong, Xiaotian
Publicado 2023

Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities

por Lecerf, Maxime, Kanyavuz, Alexia, Rossini, Sofia, Dimitrov, Jordan D.
Publicado 2021

Functional Changes of Therapeutic Antibodies upon Exposure to Pro-Oxidative Agents

por Lecerf, Maxime, Lacombe, Robin, Kanyavuz, Alexia, Dimitrov, Jordan D.
Publicado 2022

“Rational Vaccine Design” for HIV Should Take into Account the Adaptive Potential of Polyreactive Antibodies

por Dimitrov, Jordan D., Kazatchkine, Michel D., Kaveri, Srinivas V., Lacroix-Desmazes, Sebastien
Publicado 2011

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

por Hadzhieva, Maya, Pashov, Anastas D., Kaveri, Srinivas, Lacroix-Desmazes, Sébastien, Mouquet, Hugo, Dimitrov, Jordan D.
Publicado 2017

Aromatic Guanylhydrazones for the Control of Heme-Induced Antibody Polyreactivity

por Božinović, Nina, Ajdačić, Vladimir, Lazic, Jelena, Lecerf, Maxime, Daventure, Victoria, Nikodinovic-Runic, Jasmina, Opsenica, Igor M., Dimitrov, Jordan D.
Publicado 2019

Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

por Planchais, Cyril, Noe, Remi, Gilbert, Marie, Lecerf, Maxime, Kaveri, Srini V., Lacroix-Desmazes, Sébastien, Roumenina, Lubka T., Dimitrov, Jordan D.
Publicado 2023

Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies

por Wiatr, Marie, Hadzhieva, Maya, Lecerf, Maxime, Noé, Rémi, Justesen, Sune, Lacroix-Desmazes, Sébastien, Dragon-Durey, Marie-Agnès, Dimitrov, Jordan D.
Publicado 2023

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice.

por Bou-Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Astermark, Jan, Lévesque, Hervé, Dimitrov, Jordan D, Deligne, Claire, Proulle, Valérie, Lacroix-Desmazes, Sébastien
Publicado 2023

Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance

por Mimoun, Angelina, Delignat, Sandrine, Peyron, Ivan, Daventure, Victoria, Lecerf, Maxime, Dimitrov, Jordan D., Kaveri, Srinivas V., Bayry, Jagadeesh, Lacroix-Desmazes, Sébastien
Publicado 2020

Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2

por Bourne, Joshua H., Colicchia, Martina, Di, Ying, Martin, Eleyna, Slater, Alexander, Roumenina, Lubka T., Dimitrov, Jordan D., Watson, Steve P., Rayes, Julie
Publicado 2020

Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme

por Wiatr, Marie, Merle, Nicolas S., Boudhabhay, Idris, Poillerat, Victoria, Rossini, Sofia, Lecerf, Maxime, Kaveri, Srini V., Lacroix-Desmazes, Sébastian, Roumenina, Lubka T., Dimitrov, Jordan D.
Publicado 2019

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS‐CoV‐2

por Planchais, Cyril, Reyes‐Ruiz, Alejandra, Lacombe, Robin, Zarantonello, Alessandra, Lecerf, Maxime, Revel, Margot, Roumenina, Lubka T., Atanasov, Boris P., Mouquet, Hugo, Dimitrov, Jordan D.
Publicado 2022

Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin

por Galeotti, Caroline, Hegde, Pushpa, Das, Mrinmoy, Stephen-Victor, Emmanuel, Canale, Fernando, Muñoz, Marcos, Sharma, Varun K., Dimitrov, Jordan D., Kaveri, Srini V., Bayry, Jagadeesh
Publicado 2016

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

por Gupta, Nimesh, de Wispelaere, Mélissanne, Lecerf, Maxime, Kalia, Manjula, Scheel, Tobias, Vrati, Sudhanshu, Berek, Claudia, Kaveri, Srinivas V., Desprès, Philippe, Lacroix-Desmazes, Sébastien, Dimitrov, Jordan D.
Publicado 2015

HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria

por Planchais, Cyril, Molinos-Albert, Luis M., Rosenbaum, Pierre, Hieu, Thierry, Kanyavuz, Alexia, Clermont, Dominique, Prazuck, Thierry, Lefrou, Laurent, Dimitrov, Jordan D., Hüe, Sophie, Hocqueloux, Laurent, Mouquet, Hugo
Publicado 2023

Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

por Gerogianni, Alexandra, Dimitrov, Jordan D., Zarantonello, Alessandra, Poillerat, Victoria, Chonat, Satheesh, Sandholm, Kerstin, McAdam, Karin E., Ekdahl, Kristina N., Mollnes, Tom E., Mohlin, Camilla, Roumenina, Lubka T., Nilsson, Per H.
Publicado 2022

Molecular basis for bacterial peptidoglycan recognition by LysM domains

por Mesnage, Stéphane, Dellarole, Mariano, Baxter, Nicola J., Rouget, Jean-Baptiste, Dimitrov, Jordan D., Wang, Ning, Fujimoto, Yukari, Hounslow, Andrea M., Lacroix-Desmazes, Sébastien, Fukase, Koichi, Foster, Simon J., Williamson, Michael P.
Publicado 2014

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity

por Prigent, Julie, Jarossay, Annaëlle, Planchais, Cyril, Eden, Caroline, Dufloo, Jérémy, Kök, Ayrin, Lorin, Valérie, Vratskikh, Oxana, Couderc, Thérèse, Bruel, Timothée, Schwartz, Olivier, Seaman, Michael S., Ohlenschläger, Oliver, Dimitrov, Jordan D., Mouquet, Hugo
Publicado 2018

Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils

por Graeter, Stefanie, Schneider, Christoph, Verschoor, Daniëlle, von Däniken, Sandro, Seibold, Frank, Yawalkar, Nikhil, Villiger, Peter, Dimitrov, Jordan D., Smith, David F., Cummings, Richard D., Simon, Hans-Uwe, Vassilev, Tchavdar, von Gunten, Stephan
Publicado 2020