Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity

por Kietzmann, Thomas, Mennerich, Daniela, Dimova, Elitsa Y.
Publicado 2016

Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β

por Mennerich, Daniela, Dimova, Elitsa Y, Kietzmann, Thomas
Publicado 2014

Protein kinases as switches for the function of upstream stimulatory factors: implications for tissue injury and cancer

por Horbach, Tina, Götz, Claudia, Kietzmann, Thomas, Dimova, Elitsa Y.
Publicado 2015

Corrigendum: Protein kinases as switches for the function of upstream stimulatory factors: implications for tissue injury and cancer

por Horbach, Tina, Götz, Claudia, Kietzmann, Thomas, Dimova, Elitsa Y.
Publicado 2016

Cyclin-Dependent Kinase 5 (CDK5)-Mediated Phosphorylation of Upstream Stimulatory Factor 2 (USF2) Contributes to Carcinogenesis

por Chi, Tabughang Franklin, Horbach, Tina, Götz, Claudia, Kietzmann, Thomas, Dimova, Elitsa Y.
Publicado 2019

Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism

por Määttä, Jenni, Sissala, Niina, Dimova, Elitsa Y., Serpi, Raisa, Moore, Lorna G., Koivunen, Peppi
Publicado 2018

Author Correction: Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism

por Määttä, Jenni, Sissala, Niina, Dimova, Elitsa Y., Serpi, Raisa, Moore, Lorna G., Koivunen, Peppi
Publicado 2020

Resveratrol Suppresses PAI-1 Gene Expression in a Human In Vitro Model of Inflamed Adipose Tissue

por Zagotta, Ivana, Dimova, Elitsa Y., Funcke, Jan-Bernd, Wabitsch, Martin, Kietzmann, Thomas, Fischer-Posovszky, Pamela
Publicado 2013

Obesity and inflammation: reduced cytokine expression due to resveratrol in a human in vitro model of inflamed adipose tissue

por Zagotta, Ivana, Dimova, Elitsa Y., Debatin, Klaus-Michael, Wabitsch, Martin, Kietzmann, Thomas, Fischer-Posovszky, Pamela
Publicado 2015

Hypoxia ameliorates maternal diet‐induced insulin resistance during pregnancy while having a detrimental effect on the placenta

por Sissala, Niina, Myllymäki, Elisa, Mohr, Florian, Halmetoja, Riikka, Kuvaja, Paula, Dimova, Elitsa Y., Koivunen, Peppi
Publicado 2022

GSK3β-Dependent Phosphorylation Alters DNA Binding, Transactivity and Half-Life of the Transcription Factor USF2

por Horbach, Tina, Chi, Tabughang Franklin, Götz, Claudia, Sharma, Satyan, Juffer, André H., Dimova, Elitsa Y., Kietzmann, Thomas
Publicado 2014

Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2

por al Taleb, Zukaa, Petry, Andreas, Chi, Tabughang Franklin, Mennerich, Daniela, Görlach, Agnes, Dimova, Elitsa Y., Kietzmann, Thomas
Publicado 2016

Loss of USF2 promotes proliferation, migration and mitophagy in a redox-dependent manner

por Chi, Tabughang Franklin, Khoder-Agha, Fawzi, Mennerich, Daniela, Kellokumpu, Sakari, Miinalainen, IIkka, Kietzmann, Thomas, Dimova, Elitsa Y.
Publicado 2020

Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism

por Tapio, Joona, Halmetoja, Riikka, Dimova, Elitsa Y., Mäki, Joni M., Laitala, Anu, Walkinshaw, Gail, Myllyharju, Johanna, Serpi, Raisa, Koivunen, Peppi
Publicado 2022

Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?

por Görlach, Agnes, Dimova, Elitsa Y., Petry, Andreas, Martínez-Ruiz, Antonio, Hernansanz-Agustín, Pablo, Rolo, Anabela P., Palmeira, Carlos M., Kietzmann, Thomas
Publicado 2015

Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease

por Laitakari, Anna, Ollonen, Teemu, Kietzmann, Thomas, Walkinshaw, Gail, Mennerich, Daniela, Izzi, Valerio, Haapasaari, Kirsi-Maria, Myllyharju, Johanna, Serpi, Raisa, Dimova, Elitsa Y., Koivunen, Peppi
Publicado 2019

A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

por Hassinen, Antti, Khoder-Agha, Fawzi, Khosrowabadi, Elham, Mennerich, Daniela, Harrus, Deborah, Noel, Maxence, Dimova, Elitsa Y., Glumoff, Tuomo, Harduin-Lepers, Anne, Kietzmann, Thomas, Kellokumpu, Sakari
Publicado 2019

HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD

por Laitakari, Anna, Tapio, Joona, Mäkelä, Kari A., Herzig, Karl-Heinz, Dengler, Franziska, Gylling, Helena, Walkinshaw, Gail, Myllyharju, Johanna, Dimova, Elitsa Y., Serpi, Raisa, Koivunen, Peppi
Publicado 2020

The Circadian Clock Protein CRY1 Is a Negative Regulator of HIF-1α

por Dimova, Elitsa Y., Jakupovic, Mirza, Kubaichuk, Kateryna, Mennerich, Daniela, Chi, Tabughang Franklin, Tamanini, Filippo, Oklejewicz, Małgorzata, Hänig, Jens, Byts, Nadiya, Mäkelä, Kari A., Herzig, Karl-Heinz, Koivunen, Peppi, Chaves, Ines, van der Horst, Gijsbertus, Kietzmann, Thomas
Publicado 2019

Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia

por Auvinen, Juha, Tapio, Joona, Karhunen, Ville, Kettunen, Johannes, Serpi, Raisa, Dimova, Elitsa Y., Gill, Dipender, Soininen, Pasi, Tammelin, Tuija, Mykkänen, Juha, Puukka, Katri, Kähönen, Mika, Raitoharju, Emma, Lehtimäki, Terho, Ala-Korpela, Mika, Raitakari, Olli T., Keinänen-Kiukaanniemi, Sirkka, Järvelin, Marjo-Riitta, Koivunen, Peppi
Publicado 2021