Optimal control nodes in disease-perturbed networks as targets for combination therapy

por Hu, Yuxuan, Chen, Chia-hui, Ding, Yang-yang, Wen, Xiao, Wang, Bingbo, Gao, Lin, Tan, Kai
Publicado 2019

Effect of Grilled Nux Vomica on Differential RNA Expression Profile of Gastrocnemius Muscle and Toll-Like Receptor 4 (TLR-4)/Nuclear Factor kappa B (NF-κB) Signaling in Experimenta...

por Jiang, Xu Hong, Chen, Yi, Ding, Yang Yang, Qiu, Hui, Zhou, Di Yi, Qiu, Chang Lin
Publicado 2020

Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers

por He, Bing, Gao, Peng, Ding, Yang-Yang, Chen, Chia-Hui, Chen, Gregory, Chen, Changya, Kim, Hannah, Tasian, Sarah K., Hunger, Stephen P., Tan, Kai
Publicado 2020

Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia

por Ding, Yang-Yang, Kim, Hannah, Madden, Kellyn, Loftus, Joseph P., Chen, Gregory M., Allen, David Hottman, Zhang, Ruitao, Xu, Jason, Chen, Chia-Hui, Hu, Yuxuan, Tasian, Sarah K., Tan, Kai
Publicado 2021

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A-rearranged leukemia

por Chen, Changya, Yu, Wenbao, Alikarami, Fatemeh, Qiu, Qi, Chen, Chia-hui, Flournoy, Jennifer, Gao, Peng, Uzun, Yasin, Fang, Li, Davenport, James W., Hu, Yuxuan, Zhu, Qin, Wang, Kai, Libbrecht, Clara, Felmeister, Alex, Rozich, Isaiah, Ding, Yang-yang, Hunger, Stephen P., Felix, Carolyn A., Wu, Hao, Brown, Patrick A., Guest, Erin M., Barrett, David M., Bernt, Kathrin M., Tan, Kai
Publicado 2022

Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic Leukemia

por Tan, Kai, Xu, Jason, Chen, Changya, Vincent, Tiffaney, Pölönen, Petri, Hu, Jianzhong, Yoshimura, Satoshi, Yu, Wenbao, Sussman, Jonathan, Chen, Chia-hui, Li, Elizabeth, Diorio, Caroline, Shraim, Rawan, Newman, Haley, Uppuluri, Lahari, Li, Alexander, Chen, Gregory, Bandyopadhyay, Shovik, Wu, David, Ding, Yang-yang, Xu, Jessica, Lim, Tristan, Hsu, Miles, Thadi, Anusha, Ahn, Kyung Jin, Wu, Chi-Yun, Peng, Jacqueline, Sun, Yusha, Wang, Alice, Mehta, Rushabh, Frank, David, Meyer, Lauren, Loh, Mignon, Raetz, Elizabeth, Chen, Zhiguo, Wood, Brent, Devidas, Meenakshi, Dunsmore, Kimberly, Winter, Stuart, Chang, Ti-Cheng, Wu, Gang, Pounds, Stanley, Zhang, Nancy, Carroll, William, Hunger, Stephen, Bernt, Kathrin, Yang, Jun, Mullighan, Charles, Teachey, David
Publicado 2023