Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication

por Adams, Lily E., Dinnon, Kenneth H., Hou, Yixuan J., Sheahan, Timothy P., Heise, Mark T., Baric, Ralph S.
Publicado 2021

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone

por Gallichotte, Emily N., Menachery, Vineet D., Yount, Boyd L., Widman, Douglas G., Dinnon, Kenneth H., Hartman, Steven, de Silva, Aravinda M., Baric, Ralph S.
Publicado 2017

A highly immunogenic and effective measles virus-based Th1-biased COVID-19 vaccine

por Hörner, Cindy, Schürmann, Christoph, Auste, Arne, Ebenig, Aileen, Muraleedharan, Samada, Dinnon, Kenneth H., Scholz, Tatjana, Herrmann, Maike, Schnierle, Barbara S., Baric, Ralph S., Mühlebach, Michael D.
Publicado 2020

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

por Brown, Ariane J., Won, John J., Graham, Rachel L., Dinnon, Kenneth H., Sims, Amy C., Feng, Joy Y., Cihlar, Tomas, Denison, Mark R., Baric, Ralph S., Sheahan, Timothy P.
Publicado 2019

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate

por Sun, Weina, Leist, Sarah R., McCroskery, Stephen, Liu, Yonghong, Slamanig, Stefan, Oliva, Justine, Amanat, Fatima, Schäfer, Alexandra, Dinnon, Kenneth H., García-Sastre, Adolfo, Krammer, Florian, Baric, Ralph S., Palese, Peter
Publicado 2020

Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice

por Amruta, Narayanappa, Ismael, Saifudeen, Leist, Sarah R., Gressett, Timothy E., Srivastava, Akhilesh, Dinnon, Kenneth H., Engler-Chiurazzi, Elizabeth B., Maness, Nicholas J., Qin, Xuebin, Kolls, Jay K., Baric, Ralph S., Bix, Gregory
Publicado 2022

A C57BL/6 Mouse model of SARS-CoV-2 infection recapitulates age- and sex-based differences in human COVID-19 disease and recovery

por Davis, Michael, Voss, Kathleen, Turnbull, J. Bryan, Gustin, Andrew T., Knoll, Megan, Muruato, Antonio, Hsiang, Tien-Ying, Dinnon, Kenneth H., Leist, Sarah R., Nickel, Katie, Baric, Ralph S., Ladiges, Warren, Akilesh, Shreeram, Smith, Kelly D., Gale, Michael
Publicado 2022

Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection

por Menachery, Vineet D., Dinnon, Kenneth H., Yount, Boyd L., McAnarney, Eileen T., Gralinski, Lisa E., Hale, Andrew, Graham, Rachel L., Scobey, Trevor, Anthony, Simon J., Wang, Lingshu, Graham, Barney, Randell, Scott H., Lipkin, W. Ian, Baric, Ralph S.
Publicado 2020

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

por Menachery, Vineet D., Gralinski, Lisa E., Mitchell, Hugh D., Dinnon, Kenneth H., Leist, Sarah R., Yount, Boyd L., Graham, Rachel L., McAnarney, Eileen T., Stratton, Kelly G., Cockrell, Adam S., Debbink, Kari, Sims, Amy C., Waters, Katrina M., Baric, Ralph S.
Publicado 2017

Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection

por Edwards, Caitlin E., Yount, Boyd L., Graham, Rachel L., Leist, Sarah R., Hou, Yixuan J., Dinnon, Kenneth H., Sims, Amy C., Swanstrom, Jesica, Gully, Kendra, Scobey, Trevor D., Cooley, Michelle R., Currie, Caroline G., Randell, Scott H., Baric, Ralph S.
Publicado 2020

A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 Vaccine

por Sun, Weina, McCroskery, Stephen, Liu, Wen-Chun, Leist, Sarah R., Liu, Yonghong, Albrecht, Randy A., Slamanig, Stefan, Oliva, Justine, Amanat, Fatima, Schäfer, Alexandra, Dinnon, Kenneth H., Innis, Bruce L., García-Sastre, Adolfo, Krammer, Florian, Baric, Ralph S., Palese, Peter
Publicado 2020

Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2

por Tostanoski, Lisa H., Gralinski, Lisa E., Martinez, David R., Schaefer, Alexandra, Mahrokhian, Shant H., Li, Zhenfeng, Nampanya, Felix, Wan, Huahua, Yu, Jingyou, Chang, Aiquan, Liu, Jinyan, McMahan, Katherine, Dinnon, Kenneth H., Leist, Sarah R., Baric, Ralph S., Barouch, Dan H.
Publicado 2021

Protective Efficacy of Rhesus Adenovirus COVID-19 Vaccines against Mouse-Adapted SARS-CoV-2

por Tostanoski, Lisa H., Gralinski, Lisa E., Martinez, David R., Schaefer, Alexandra, Mahrokhian, Shant H., Li, Zhenfeng, Nampanya, Felix, Wan, Huahua, Yu, Jingyou, Chang, Aiquan, Liu, Jinyan, McMahan, Katherine, Ventura, John D., Dinnon, Kenneth H., Leist, Sarah R., Baric, Ralph S., Barouch, Dan H.
Publicado 2021

A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice

por Leist, Sarah R., Dinnon, Kenneth H., Schäfer, Alexandra, Tse, Longping V., Okuda, Kenichi, Hou, Yixuan J., West, Ande, Edwards, Caitlin E., Sanders, Wes, Fritch, Ethan J., Gully, Kendra L., Scobey, Trevor, Brown, Ariane J., Sheahan, Timothy P., Moorman, Nathaniel J., Boucher, Richard C., Gralinski, Lisa E., Montgomery, Stephanie A., Baric, Ralph S.
Publicado 2020

SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo

por Hou, Yixuan J., Chiba, Shiho, Halfmann, Peter, Ehre, Camille, Kuroda, Makoto, Dinnon, Kenneth H, Leist, Sarah R., Schäfer, Alexandra, Nakajima, Noriko, Takahashi, Kenta, Lee, Rhianna E., Mascenik, Teresa M., Edwards, Caitlin E., Tse, Longping V., Boucher, Richard C., Randell, Scott H., Suzuki, Tadaki, Gralinski, Lisa E., Kawaoka, Yoshihiro, Baric, Ralph S.
Publicado 2020

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

por Dinnon, Kenneth H., Leist, Sarah R., Schäfer, Alexandra, Edwards, Caitlin E., Martinez, David R., Montgomery, Stephanie A., West, Ande, Yount, Boyd L., Hou, Yixuan J., Adams, Lily E., Gully, Kendra L., Brown, Ariane J., Huang, Emily, Bryant, Matthew D., Choong, Ingrid C., Glenn, Jeffrey S., Gralinski, Lisa E., Sheahan, Timothy P., Baric, Ralph S.
Publicado 2020

Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection

por Geng, Qibin, Tai, Wanbo, Baxter, Victoria K., Shi, Juan, Wan, Yushun, Zhang, Xiujuan, Montgomery, Stephanie A., Taft-Benz, Sharon A., Anderson, Elizabeth J., Knight, Audrey C., Dinnon, Kenneth H., Leist, Sarah R., Baric, Ralph S., Shang, Jian, Hong, Sung-Wook, Drelich, Aleksandra, Tseng, Chien-Te K., Jenkins, Marc, Heise, Mark, Du, Lanying, Li, Fang
Publicado 2021

Stabilized coronavirus spike stem elicits a broadly protective antibody

por Hsieh, Ching-Lin, Werner, Anne P., Leist, Sarah R., Stevens, Laura J., Falconer, Ester, Goldsmith, Jory A., Chou, Chia-Wei, Abiona, Olubukola M., West, Ande, Westendorf, Kathryn, Muthuraman, Krithika, Fritch, Ethan J., Dinnon, Kenneth H., Schäfer, Alexandra, Denison, Mark R., Chappell, James D., Baric, Ralph S., Graham, Barney S., Corbett, Kizzmekia S., McLellan, Jason S.
Publicado 2021

SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung

por Routhu, Nanda Kishore, Cheedarla, Narayanaiah, Bollimpelli, Venkata Satish, Gangadhara, Sailaja, Edara, Venkata Viswanadh, Lai, Lilin, Sahoo, Anusmita, Shiferaw, Ayalnesh, Styles, Tiffany M., Floyd, Katharine, Fischinger, Stephanie, Atyeo, Caroline, Shin, Sally A., Gumber, Sanjeev, Kirejczyk, Shannon, Dinnon, Kenneth H., Shi, Pei-Yong, Menachery, Vineet D., Tomai, Mark, Fox, Christopher B., Alter, Galit, Vanderford, Thomas H., Gralinski, Lisa, Suthar, Mehul S., Amara, Rama Rao
Publicado 2021

Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination

por Adams, Lily E., Leist, Sarah R., Dinnon, Kenneth H., West, Ande, Gully, Kendra L., Anderson, Elizabeth J., Loome, Jennifer F., Madden, Emily A., Powers, John M., Schäfer, Alexandra, Sarkar, Sanjay, Castillo, Izabella N., Maron, Jenny S., McNamara, Ryan P., Bertera, Harry L., Zweigart, Mark R., Higgins, Jaclyn S., Hampton, Brea K., Premkumar, Lakshmanane, Alter, Galit, Montgomery, Stephanie A., Baxter, Victoria K., Heise, Mark T., Baric, Ralph S.
Publicado 2023