Identifying the Preferred RNA Motifs and Chemotypes that Interact by Probing Millions of Combinations

por Tran, Tuan, Disney, Matthew D.
Publicado 2012

Carbohydrate arrays as tools for the glycomics revolution

por Disney, Matthew D, Seeberger, Peter H
Publicado 2004

Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside–RNA hairpin loop interactions

por Paul, Dustin J., Seedhouse, Steven J., Disney, Matthew D.
Publicado 2009

A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat RNA

por Strack, Rita L., Disney, Matthew D., Jaffrey, Samie R.
Publicado 2013

Sequence-based design of bioactive small molecules that target precursor microRNAs

por Velagapudi, Sai Pradeep, Gallo, Steven M., Disney, Matthew D.
Publicado 2014

Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10

por Yang, Wang-Yong, Gao, Rui, Southern, Mark, Sarkar, Partha S., Disney, Matthew D.
Publicado 2016

Conformational dynamics of RNA G(4)C(2) and G(2)C(4) repeat expansions causing ALS/FTD using NMR and molecular dynamics studies

por Taghavi, Amirhossein, Baisden, Jared T, Childs-Disney, Jessica L, Yildirim, Ilyas, Disney, Matthew D
Publicado 2023

Computational Investigation of RNA CUG Repeats Responsible for Myotonic Dystrophy 1

por Yildirim, Ilyas, Chakraborty, Debayan, Disney, Matthew D., Wales, David J., Schatz, George C.
Publicado 2015

Controlled dehydration improves the diffraction quality of two RNA crystals

por Park, HaJeung, Tran, Tuan, Lee, Jun Hyuck, Park, Hyun, Disney, Matthew D.
Publicado 2016

Broad-spectrum metastasis suppressing compounds and therapeutic uses thereof in human tumors

por Komlosh, Pnina Gottfried, Chen, Jonathan L., Childs-Disney, Jessica, Disney, Matthew D., Canaani, Dan
Publicado 2023

Targeting the r(CGG) Repeats That Cause FXTAS with Modularly Assembled Small Molecules and Oligonucleotides

por Tran, Tuan, Childs-Disney, Jessica L., Liu, Biao, Guan, Lirui, Rzuczek, Suzanne, Disney, Matthew D.
Publicado 2014

The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology

por Chen, Jonathan L., Moss, Walter N., Spencer, Adam, Zhang, Peiyuan, Childs-Disney, Jessica L., Disney, Matthew D.
Publicado 2019

Targeting RNA structures with small molecules

por Childs-Disney, Jessica L., Yang, Xueyi, Gibaut, Quentin M. R., Tong, Yuquan, Batey, Robert T., Disney, Matthew D.
Publicado 2022

A general fragment-based approach to identify and optimize bioactive ligands targeting RNA

por Suresh, Blessy M., Li, Weichao, Zhang, Peiyuan, Wang, Kye Won, Yildirim, Ilyas, Parker, Christopher G., Disney, Matthew D.
Publicado 2020

Analysis of secondary structural elements in human microRNA hairpin precursors

por Liu, Biao, Childs-Disney, Jessica L., Znosko, Brent M., Wang, Dan, Fallahi, Mohammad, Gallo, Steven M., Disney, Matthew D.
Publicado 2016

An in silico map of the SARS-CoV-2 RNA Structurome

por Andrews, Ryan J., Peterson, Jake M., Haniff, Hafeez S., Chen, Jonathan, Williams, Christopher, Grefe, Maison, Disney, Matthew D., Moss, Walter N.
Publicado 2020

RNA structural analysis of the MYC mRNA reveals conserved motifs that affect gene expression

por O’Leary, Collin A., Andrews, Ryan J., Tompkins, Van S., Chen, Jonathan L., Childs-Disney, Jessica L., Disney, Matthew D., Moss, Walter N.
Publicado 2019

A map of the SARS-CoV-2 RNA structurome

por Andrews, Ryan J, O’Leary, Collin A, Tompkins, Van S, Peterson, Jake M, Haniff, Hafeez S, Williams, Christopher, Disney, Matthew D, Moss, Walter N
Publicado 2021

Defining RNA–Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA

por Velagapudi, Sai Pradeep, Luo, Yiling, Tran, Tuan, Haniff, Hafeez S., Nakai, Yoshio, Fallahi, Mohammad, Martinez, Gustavo J., Childs-Disney, Jessica L., Disney, Matthew D.
Publicado 2017

Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model

por Angelbello, Alicia J., Rzuczek, Suzanne G., Mckee, Kendra K., Chen, Jonathan L., Olafson, Hailey, Cameron, Michael D., Moss, Walter N., Wang, Eric T., Disney, Matthew D.
Publicado 2019