Measuring CPT-1-mediated respiration in permeabilized cells and isolated mitochondria

por Yang, Krista, Doan, Mary T., Stiles, Linsey, Divakaruni, Ajit S.
Publicado 2021

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

por Ding, Boxiao, Parmigiani, Anita, Divakaruni, Ajit S., Archer, Kellie, Murphy, Anne N., Budanov, Andrei V.
Publicado 2016

Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury

por Cordes, Thekla, Lucas, Alfredo, Divakaruni, Ajit S., Murphy, Anne N., Cabrales, Pedro, Metallo, Christian M.
Publicado 2019

A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs

por Jones, Anthony E., Arias, Nataly J., Acevedo, Aracely, Reddy, Srinivasa T., Divakaruni, Ajit S., Meriwether, David
Publicado 2021

Branched chain amino acid catabolism fuels adipocyte differentiation and lipogenesis

por Green, Courtney R., Wallace, Martina, Divakaruni, Ajit S., Phillips, Susan A., Murphy, Anne N., Ciaraldi, Theodore P., Metallo, Christian M.
Publicado 2015

Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium

por Hazim, Roni A., Paniagua, Antonio E., Tang, Lisa, Yang, Krista, Kim, Kristen K.O., Stiles, Linsey, Divakaruni, Ajit S., Williams, David S.
Publicado 2022

Correction: Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium

por Hazim, Roni A., Paniagua, Antonio E., Tang, Lisa, Yang, Krista, Kim, Kristen K.O., Stiles, Linsey, Divakaruni, Ajit S., Williams, David S.
Publicado 2022

A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates

por Fernandez-del-Rio, Lucia, Benincá, Cristiane, Villalobos, Frankie, Shu, Cynthia, Stiles, Linsey, Liesa, Marc, Divakaruni, Ajit S, Acin-Perez, Rebeca, Shirihai, Orian S
Publicado 2023

Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span

por Sessions, Ayla O., Min, Peter, Cordes, Thekla, Weickert, Barry J., Divakaruni, Ajit S., Murphy, Anne N., Metallo, Christian M., Engler, Adam J.
Publicado 2018

Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity

por Jacques, Vincent, Bolze, Sébastien, Hallakou‐Bozec, Sophie, Czarnik, Anthony W., Divakaruni, Ajit S., Fouqueray, Pascale, Murphy, Anne N., Van der Ploeg, Lex H.T., DeWitt, Sheila
Publicado 2021

GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop

por Giacco, Ferdinando, Du, Xueliang, Carratú, Anna, Gerfen, Gary J., D’Apolito, Maria, Giardino, Ida, Rasola, Andrea, Marin, Oriano, Divakaruni, Ajit S., Murphy, Anne N., Shah, Manasi S., Brownlee, Michael
Publicado 2015

The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis

por Acevedo, Aracely, Jones, Anthony E., Danna, Bezawit T., Turner, Rory, Montales, Katrina P., Benincá, Cristiane, Reue, Karen, Shirihai, Orian S., Stiles, Linsey, Wallace, Martina, Wang, Yibin, Bertholet, Ambre M., Divakaruni, Ajit S.
Publicado 2023

Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

por Yan, Tianyang, Julio, Ashley R., Villanueva, Miranda, Jones, Anthony E., Ball, Andréa B., Boatner, Lisa M., Turmon, Alexandra C., Yen, Stephanie L., Desai, Heta S., Divakaruni, Ajit S., Backus, Keriann M.
Publicado 2023

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

por Divakaruni, Ajit S., Wallace, Martina, Buren, Caodu, Martyniuk, Kelly, Andreyev, Alexander Y., Li, Edward, Fields, Jerel A., Cordes, Thekla, Reynolds, Ian J., Bloodgood, Brenda L., Raymond, Lynn A., Metallo, Christian M., Murphy, Anne N.
Publicado 2017

Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function

por Wortham, Matthew, Benthuysen, Jacqueline R., Wallace, Martina, Savas, Jeffrey N., Mulas, Francesca, Divakaruni, Ajit S., Liu, Fenfen, Albert, Verena, Taylor, Brandon L., Sui, Yinghui, Saez, Enrique, Murphy, Anne N., Yates, John R., Metallo, Christian M., Sander, Maike
Publicado 2018

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca(2+) homeostasis

por Wiley, Sandra E, Andreyev, Alexander Y, Divakaruni, Ajit S, Karisch, Robert, Perkins, Guy, Wall, Estelle A, van der Geer, Peter, Chen, Yi-Fan, Tsai, Ting-Fen, Simon, Melvin I, Neel, Benjamin G, Dixon, Jack E, Murphy, Anne N
Publicado 2013

Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy

por Sperry, Jantzen, Condro, Michael C., Guo, Lea, Braas, Daniel, Vanderveer-Harris, Nathan, Kim, Kristen K.O., Pope, Whitney B., Divakaruni, Ajit S., Lai, Albert, Christofk, Heather, Castro, Maria G., Lowenstein, Pedro R., Le Belle, Janel E., Kornblum, Harley I.
Publicado 2020

Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner

por Chella Krishnan, Karthickeyan, Floyd, Raquel R., Sabir, Simon, Jayasekera, Dulshan W., Leon-Mimila, Paola V., Jones, Anthony E., Cortez, Angel A., Shravah, Varun, Péterfy, Miklós, Stiles, Linsey, Canizales-Quinteros, Samuel, Divakaruni, Ajit S., Huertas-Vazquez, Adriana, Lusis, Aldons J.
Publicado 2020

Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells

por Tucci, Jonathan, Chen, Ting, Margulis, Katherine, Orgel, Etan, Paszkiewicz, Rebecca L., Cohen, Michael D., Oberley, Matthew J., Wahhab, Rachel, Jones, Anthony E., Divakaruni, Ajit S., Hsu, Cheng-Chih, Noll, Sarah E., Sheng, Xia, Zare, Richard N., Mittelman, Steven D.
Publicado 2021

Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair

por Meriwether, David, Jones, Anthony E., Ashby, Julianne W., Solorzano-Vargas, R. Sergio, Dorreh, Nasrin, Noori, Shoreh, Grijalva, Victor, Ball, Andréa B., Semis, Margarita, Divakaruni, Ajit S., Mack, Julia J., Herschman, Harvey R., Martin, Martin G., Fogelman, Alan M., Reddy, Srinivasa T.
Publicado 2022