Mutant HER2 needs mutant HER3 to be an effective oncogene

por Trenker, Raphael, Diwanji, Devan, Jura, Natalia
Publicado 2021

Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3

por Torosyan, Hayarpi, Paul, Michael D., Forget, Antoine, Lo, Megan, Diwanji, Devan, Pawłowski, Krzysztof, Krogan, Nevan J., Jura, Natalia, Verba, Kliment A.
Publicado 2023

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer

por Sarkar, Anita, Bale, Shridhar, Behrens, Anna-Janina, Kumar, Sonu, Sharma, Shailendra Kumar, de Val, Natalia, Pallesen, Jesper, Irimia, Adriana, Diwanji, Devan C., Stanfield, Robyn L., Ward, Andrew B., Crispin, Max, Wyatt, Richard T., Wilson, Ian A.
Publicado 2018

Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein

por Weinberg, Zara Y., Hilburger, Claire E., Kim, Matthew, Cao, Longxing, Khalid, Mir, Elmes, Sarah, Diwanji, Devan, Hernandez, Evelyn, Lopez, Jocelyne, Schaefer, Kaitlin, Smith, Amber M., Zhou, Fengbo, Kumar, G. Renuka, Ott, Melanie, Baker, David, El-Samad, Hana
Publicado 2021

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

por Julien, Jean-Philippe, Sok, Devin, Khayat, Reza, Lee, Jeong Hyun, Doores, Katie J., Walker, Laura M., Ramos, Alejandra, Diwanji, Devan C., Pejchal, Robert, Cupo, Albert, Katpally, Umesh, Depetris, Rafael S., Stanfield, Robyn L., McBride, Ryan, Marozsan, Andre J., Paulson, James C., Sanders, Rogier W., Moore, John P., Burton, Dennis R., Poignard, Pascal, Ward, Andrew B., Wilson, Ian A.
Publicado 2013

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

por Jardine, Joseph G., Sok, Devin, Julien, Jean-Philippe, Briney, Bryan, Sarkar, Anita, Liang, Chi-Hui, Scherer, Erin A., Henry Dunand, Carole J., Adachi, Yumiko, Diwanji, Devan, Hsueh, Jessica, Jones, Meaghan, Kalyuzhniy, Oleksandr, Kubitz, Michael, Spencer, Skye, Pauthner, Matthias, Saye-Francisco, Karen L., Sesterhenn, Fabian, Wilson, Patrick C., Galloway, Denise M., Stanfield, Robyn L., Wilson, Ian A., Burton, Dennis R., Schief, William R.
Publicado 2016

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

por Jardine, Joseph G., Sok, Devin, Julien, Jean-Philippe, Briney, Bryan, Sarkar, Anita, Liang, Chi-Hui, Scherer, Erin M., Henry Dunand, Carole J., Adachi, Yumiko, Diwanji, Devan, Hsueh, Jessica, Jones, Meaghan, Kalyuzhniy, Oleksandr, Kubitz, Michael, Spencer, Skye, Pauthner, Matthias, Saye-Francisco, Karen L., Sesterhenn, Fabian, Wilson, Patrick C., Galloway, Denise A., Stanfield, Robyn L., Wilson, Ian A., Burton, Dennis R., Schief, William R.
Publicado 2016

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

por Remesh, Soumya G., Merz, Gregory E., Brilot, Axel F., Chio, Un Seng, Rizo, Alexandrea N., Pospiech, Thomas H., Lui, Irene, Laurie, Mathew T., Glasgow, Jeff, Le, Chau Q., Zhang, Yun, Diwanji, Devan, Hernandez, Evelyn, Lopez, Jocelyne, Pawar, Komal Ishwar, Pourmal, Sergei, Smith, Amber M., Zhou, Fengbo, DeRisi, Joseph, Kortemme, Tanja, Rosenberg, Oren S., Glasgow, Anum, Leung, Kevin K., Wells, James A., Verba, Kliment A.
Publicado 2022

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

por Remesh, Soumya G., Merz, Gregory E., Brilot, Axel F., Chio, Un Seng, Rizo, Alexandrea N., Pospiech, Thomas H., Lui, Irene, Laurie, Mathew T., Glasgow, Jeff, Le, Chau Q., Zhang, Yun, Diwanji, Devan, Hernandez, Evelyn, Lopez, Jocelyne, Mehmood, Hevatib, Pawar, Komal Ishwar, Pourmal, Sergei, Smith, Amber M., Zhou, Fengbo, DeRisi, Joseph, Kortemme, Tanja, Rosenberg, Oren S., Glasgow, Anum, Leung, Kevin K., Wells, James A., Verba, Kliment A.
Publicado 2023

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2

por Suryamohan, Kushal, Diwanji, Devan, Stawiski, Eric W., Gupta, Ravi, Miersch, Shane, Liu, Jiang, Chen, Chao, Jiang, Ying-Ping, Fellouse, Frederic A., Sathirapongsasuti, J. Fah, Albers, Patrick K., Deepak, Tanneeru, Saberianfar, Reza, Ratan, Aakrosh, Washburn, Gavin, Mis, Monika, Santhosh, Devi, Somasekar, Sneha, Hiranjith, G. H., Vargas, Derek, Mohan, Sangeetha, Phalke, Sameer, Kuriakose, Boney, Antony, Aju, Ustav Jr, Mart, Schuster, Stephan C., Sidhu, Sachdev, Junutula, Jagath R., Jura, Natalia, Seshagiri, Somasekar
Publicado 2021

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

por Schoof, Michael, Faust, Bryan, Saunders, Reuben A., Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B., Puchades, Cristina, Azumaya, Caleigh M., Kratochvil, Huong T., Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C., Chio, Cynthia M., Merz, Gregory E., Thompson, Michael C., Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A., Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R., Leon, Kristoffer, White, Kris M., Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M., Rizo, Alexandrea N., Moss, Frank, Brilot, Axel F., Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W., Nock, Silke, Liu, Yuwei, Krogan, Nevan J., Ralston, Corie Y., Swaney, Danielle L., García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish
Publicado 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

por Schoof, Michael, Faust, Bryan, Saunders, Reuben A., Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B., Puchades, Cristina, Azumaya, Caleigh M., Kratochvil, Huong T., Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C., Chio, Cynthia M., Merz, Gregory E., Thompson, Michael C., Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A., Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R., Leon, Kristoffer, White, Kris M., Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M., Rizo, Alexandrea N., Moss, Frank, Brilot, Axel F., Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W., Nock, Silke, Liu, Yuwei, Krogan, Nevan J., Ralston, Corie Y., Swaney, Danielle L., García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish
Publicado 2020

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

por Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Publicado 2021

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

por Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Publicado 2021

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

por Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J.
Publicado 2020