Targeting RIP Kinases in Chronic Inflammatory Disease

por Speir, Mary, Djajawi, Tirta M., Conos, Stephanie A., Tye, Hazel, Lawlor, Kate E.
Publicado 2021

A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation

por Speir, Mary, Tye, Hazel, Gottschalk, Timothy A, Simpson, Daniel S, Djajawi, Tirta M, Deo, Pankaj, Ambrose, Rebecca L, Conos, Stephanie A, Emery, Jack, Abraham, Gilu, Pascoe, Ashlyn, Hughes, Sebastian A, Weir, Ashley, Hawkins, Edwin D, Kong, Isabella, Herold, Marco J, Pearson, Jaclyn S, Lalaoui, Najoua, Naderer, Thomas, Vince, James E, Lawlor, Kate E
Publicado 2023

Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy

por Thijssen, Rachel, Tian, Luyi, Anderson, Mary Ann, Flensburg, Christoffer, Jarratt, Andrew, Garnham, Alexandra L., Jabbari, Jafar S., Peng, Hongke, Lew, Thomas E., Teh, Charis E., Gouil, Quentin, Georgiou, Angela, Tan, Tania, Djajawi, Tirta M., Tam, Constantine S., Seymour, John F., Blombery, Piers, Gray, Daniel H.D., Majewski, Ian J., Ritchie, Matthew E., Roberts, Andrew W., Huang, David C.S.
Publicado 2022

RIPK3 controls MAIT cell accumulation during development but not during infection

por Patton, Timothy, Zhao, Zhe, Lim, Xin Yi, Eddy, Eleanor, Wang, Huimeng, Nelson, Adam G., Ennis, Bronte, Eckle, Sidonia B. G., Souter, Michael N. T., Pediongco, Troi J., Koay, Hui-Fern, Zhang, Jian-Guo, Djajawi, Tirta M., Louis, Cynthia, Lalaoui, Najoua, Jacquelot, Nicolas, Lew, Andrew M., Pellicci, Daniel G., McCluskey, James, Zhan, Yifan, Chen, Zhenjun, Lawlor, Kate E., Corbett, Alexandra J.
Publicado 2023

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

por Simpson, Daniel S., Pang, Jiyi, Weir, Ashley, Kong, Isabella Y., Fritsch, Melanie, Rashidi, Maryam, Cooney, James P., Davidson, Kathryn C., Speir, Mary, Djajawi, Tirta M., Hughes, Sebastian, Mackiewicz, Liana, Dayton, Merle, Anderton, Holly, Doerflinger, Marcel, Deng, Yexuan, Huang, Allan Shuai, Conos, Stephanie A., Tye, Hazel, Chow, Seong H., Rahman, Arfatur, Norton, Raymond S., Naderer, Thomas, Nicholson, Sandra E., Burgio, Gaetan, Man, Si Ming, Groom, Joanna R., Herold, Marco J., Hawkins, Edwin D., Lawlor, Kate E., Strasser, Andreas, Silke, John, Pellegrini, Marc, Kashkar, Hamid, Feltham, Rebecca, Vince, James E.
Publicado 2022