Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases

por Dobó, József, Kocsis, Andrea, Gál, Péter
Publicado 2018

Editorial: Complement: Latest developments regarding structure, mechanism, and connections to other proteolytic pathways

por Dobó, József, Gál, Péter, Geisbrecht, Brian V.
Publicado 2023

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

por Jenny, Lorenz, Dobó, József, Gál, Péter, Schroeder, Verena
Publicado 2015

Proprotein Convertases and the Complement System

por Dobó, József, Kocsis, Andrea, Dani, Ráhel, Gál, Péter
Publicado 2022

Effects of MASP-1 of the Complement System on Activation of Coagulation Factors and Plasma Clot Formation

por Hess, Katharina, Ajjan, Ramzi, Phoenix, Fladia, Dobó, József, Gál, Péter, Schroeder, Verena
Publicado 2012

Cooperation of Complement MASP-1 with Other Proinflammatory Factors to Enhance the Activation of Endothelial Cells

por Németh, Zsuzsanna, Debreczeni, Márta L., Kajdácsi, Erika, Dobó, József, Gál, Péter, Cervenak, László
Publicado 2023

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model

por Jenny, Lorenz, Dobó, József, Gál, Péter, Pál, Gábor, Lam, Wilbur A., Schroeder, Verena
Publicado 2018

Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism

por Oroszlán, Gábor, Dani, Ráhel, Szilágyi, András, Závodszky, Péter, Thiel, Steffen, Gál, Péter, Dobó, József
Publicado 2017

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

por De Marco Verissimo, Carolina, Jewhurst, Heather L., Dobó, József, Gál, Péter, Dalton, John P., Cwiklinski, Krystyna
Publicado 2022

Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D

por Dani, Ráhel, Oroszlán, Gábor, Martinusz, Róbert, Farkas, Bence, Dobos, Bernadett, Vadas, Evelin, Závodszky, Péter, Gál, Péter, Dobó, József
Publicado 2023

Cleavage of Kininogen and Subsequent Bradykinin Release by the Complement Component: Mannose-Binding Lectin-Associated Serine Protease (MASP)-1

por Dobó, József, Major, Balázs, Kékesi, Katalin A., Szabó, István, Megyeri, Márton, Hajela, Krishnan, Juhász, Gábor, Závodszky, Péter, Gál, Péter
Publicado 2011

Human primary endothelial label-free biochip assay reveals unpredicted functions of plasma serine proteases

por Debreczeni, Márta Lídia, Szekacs, Inna, Kovacs, Boglarka, Saftics, Andras, Kurunczi, Sándor, Gál, Péter, Dobó, József, Cervenak, László, Horvath, Robert
Publicado 2020

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

por Dobó, József, Szakács, Dávid, Oroszlán, Gábor, Kortvely, Elod, Kiss, Bence, Boros, Eszter, Szász, Róbert, Závodszky, Péter, Gál, Péter, Pál, Gábor
Publicado 2016

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model

por Golomingi, Murielle, Kohler, Jessie, Jenny, Lorenz, Hardy, Elaissa T., Dobó, József, Gál, Péter, Pál, Gábor, Kiss, Bence, Lam, Wilbur A., Schroeder, Verena
Publicado 2022

Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum

por Nagy, Zoltán Attila, Szakács, Dávid, Boros, Eszter, Héja, Dávid, Vígh, Eszter, Sándor, Noémi, Józsi, Mihály, Oroszlán, Gábor, Dobó, József, Gál, Péter, Pál, Gábor
Publicado 2019

MASP-1 Induces a Unique Cytokine Pattern in Endothelial Cells: A Novel Link between Complement System and Neutrophil Granulocytes

por Jani, Péter K., Kajdácsi, Erika, Megyeri, Márton, Dobó, József, Doleschall, Zoltán, Futosi, Krisztina, Tímár, Csaba I., Mócsai, Attila, Makó, Veronika, Gál, Péter, Cervenak, László
Publicado 2014

Transcriptome analysis of inflammation-related gene expression in endothelial cells activated by complement MASP-1

por Schwaner, Endre, Németh, Zsuzsanna, Jani, Péter K., Kajdácsi, Erika, Debreczeni, Márta L., Doleschall, Zoltán, Dobó, József, Gál, Péter, Rigó, János, András, Kinga, Hegedűs, Tamás, Cervenak, László
Publicado 2017

Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation

por Nagy, Zoltán Attila, Héja, Dávid, Bencze, Dániel, Kiss, Bence, Boros, Eszter, Szakács, Dávid, Fodor, Krisztián, Wilmanns, Matthias, Kocsis, Andrea, Dobó, József, Gál, Péter, Harmat, Veronika, Pál, Gábor
Publicado 2022

ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism

por Pihl, Rasmus, Jensen, Rasmus K., Poulsen, Emil C., Jensen, Lisbeth, Hansen, Annette G., Thøgersen, Ida B., Dobó, József, Gál, Péter, Andersen, Gregers R., Enghild, Jan J., Thiel, Steffen
Publicado 2021

Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels

por Golomingi, Murielle, Kohler, Jessie, Lamers, Christina, Pouw, Richard B., Ricklin, Daniel, Dobó, József, Gál, Péter, Pál, Gábor, Kiss, Bence, Dopler, Arthur, Schmidt, Christoph Q., Hardy, Elaissa Trybus, Lam, Wilbur, Schroeder, Verena
Publicado 2023