Protein Misfolding and Human Disease

di Dobson, Christopher
Pubblicazione 2002

Immunological features of α-synuclein in Parkinson's disease

di Roodveldt, Cintia, Christodoulou, John, Dobson, Christopher M
Pubblicazione 2008

A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation

di Kundra, Rishika, Dobson, Christopher M., Vendruscolo, Michele
Pubblicazione 2020

Nature and Regulation of Protein Folding on the Ribosome

di Waudby, Christopher A., Dobson, Christopher M., Christodoulou, John
Pubblicazione 2019

A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates

di Auer, Stefan, Meersman, Filip, Dobson, Christopher M., Vendruscolo, Michele
Pubblicazione 2008

A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation

di Abeln, Sanne, Vendruscolo, Michele, Dobson, Christopher M., Frenkel, Daan
Pubblicazione 2014

Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy

di Bodner, Christina R., Maltsev, Alexander S., Dobson, Christopher M., Bax, Ad
Pubblicazione 2009

An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation

di Yates, Emma V., Meisl, Georg, Knowles, Tuomas P. J., Dobson, Christopher M.
Pubblicazione 2016

The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis

di Hanspal, Maya A., Dobson, Christopher M., Yerbury, Justin J., Kumita, Janet R.
Pubblicazione 2017

The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State

di Runfola, Matteo, De Simone, Alfonso, Vendruscolo, Michele, Dobson, Christopher M., Fusco, Giuliana
Pubblicazione 2020

Parallel and Sequential Pathways of Molecular Recognition of a Tandem-Repeat Protein and Its Intrinsically Disordered Binding Partner

di Smith, Ben M., Rowling, Pamela J. E., Dobson, Christopher M., Itzhaki, Laura S.
Pubblicazione 2021

The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes

di Fusco, Giuliana, Bemporad, Francesco, Chiti, Fabrizio, Dobson, Christopher M., De Simone, Alfonso
Pubblicazione 2022

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

di Cohen, Samuel I. A., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Pubblicazione 2011

Structure of a low-population intermediate state in the release of an enzyme product

di De Simone, Alfonso, Aprile, Francesco A, Dhulesia, Anne, Dobson, Christopher M, Vendruscolo, Michele
Pubblicazione 2015

A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer’s disease

di Freer, Rosie, Sormanni, Pietro, Vecchi, Giulia, Ciryam, Prajwal, Dobson, Christopher M., Vendruscolo, Michele
Pubblicazione 2016

Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants

di Meisl, Georg, Yang, Xiaoting, Dobson, Christopher M., Linse, Sara, Knowles, Tuomas P. J.
Pubblicazione 2017

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

di Macao, Bertil, Hoyer, Wolfgang, Sandberg, Anders, Brorsson, Ann-Christin, Dobson, Christopher M, Härd, Torleif
Pubblicazione 2008

The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila

di Gregory, Jenna M., Barros, Teresa P., Meehan, Sarah, Dobson, Christopher M., Luheshi, Leila M.
Pubblicazione 2012

A Label-Free, Quantitative Assay of Amyloid Fibril Growth Based on Intrinsic Fluorescence

di Pinotsi, Dorothea, Buell, Alexander K, Dobson, Christopher M, Kaminski Schierle, Gabriele S, Kaminski, Clemens F
Pubblicazione 2013