Immunological features of α-synuclein in Parkinson's disease

por Roodveldt, Cintia, Christodoulou, John, Dobson, Christopher M
Publicado 2008

A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation

por Kundra, Rishika, Dobson, Christopher M., Vendruscolo, Michele
Publicado 2020

Nature and Regulation of Protein Folding on the Ribosome

por Waudby, Christopher A., Dobson, Christopher M., Christodoulou, John
Publicado 2019

A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates

por Auer, Stefan, Meersman, Filip, Dobson, Christopher M., Vendruscolo, Michele
Publicado 2008

A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation

por Abeln, Sanne, Vendruscolo, Michele, Dobson, Christopher M., Frenkel, Daan
Publicado 2014

Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy

por Bodner, Christina R., Maltsev, Alexander S., Dobson, Christopher M., Bax, Ad
Publicado 2009

An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation

por Yates, Emma V., Meisl, Georg, Knowles, Tuomas P. J., Dobson, Christopher M.
Publicado 2016

The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis

por Hanspal, Maya A., Dobson, Christopher M., Yerbury, Justin J., Kumita, Janet R.
Publicado 2017

The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State

por Runfola, Matteo, De Simone, Alfonso, Vendruscolo, Michele, Dobson, Christopher M., Fusco, Giuliana
Publicado 2020

Parallel and Sequential Pathways of Molecular Recognition of a Tandem-Repeat Protein and Its Intrinsically Disordered Binding Partner

por Smith, Ben M., Rowling, Pamela J. E., Dobson, Christopher M., Itzhaki, Laura S.
Publicado 2021

The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes

por Fusco, Giuliana, Bemporad, Francesco, Chiti, Fabrizio, Dobson, Christopher M., De Simone, Alfonso
Publicado 2022

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

por Cohen, Samuel I. A., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Publicado 2011

Structure of a low-population intermediate state in the release of an enzyme product

por De Simone, Alfonso, Aprile, Francesco A, Dhulesia, Anne, Dobson, Christopher M, Vendruscolo, Michele
Publicado 2015

A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer’s disease

por Freer, Rosie, Sormanni, Pietro, Vecchi, Giulia, Ciryam, Prajwal, Dobson, Christopher M., Vendruscolo, Michele
Publicado 2016

Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants

por Meisl, Georg, Yang, Xiaoting, Dobson, Christopher M., Linse, Sara, Knowles, Tuomas P. J.
Publicado 2017

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

por Macao, Bertil, Hoyer, Wolfgang, Sandberg, Anders, Brorsson, Ann-Christin, Dobson, Christopher M, Härd, Torleif
Publicado 2008

The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila

por Gregory, Jenna M., Barros, Teresa P., Meehan, Sarah, Dobson, Christopher M., Luheshi, Leila M.
Publicado 2012

A Label-Free, Quantitative Assay of Amyloid Fibril Growth Based on Intrinsic Fluorescence

por Pinotsi, Dorothea, Buell, Alexander K, Dobson, Christopher M, Kaminski Schierle, Gabriele S, Kaminski, Clemens F
Publicado 2013

A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein

por Allison, Jane R., Rivers, Robert C., Christodoulou, John C., Vendruscolo, Michele, Dobson, Christopher M.
Publicado 2014

Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity

por Fusco, Giuliana, De Simone, Alfonso, Arosio, Paolo, Vendruscolo, Michele, Veglia, Gianluigi, Dobson, Christopher M.
Publicado 2016