Editorial: Structural and Biochemical Aspects of the Interaction of β-Lactamases With State-of-the-Art Inhibitors

por Papp-Wallace, Krisztina M., Docquier, Jean-Denis, Kerff, Frederic, Power, Pablo
Publicado 2022

Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens

por Dalla Torre, Chiara, Sannio, Filomena, Battistella, Mattia, Docquier, Jean-Denis, De Zotti, Marta
Publicado 2023

Effect of High N-Acetylcysteine Concentrations on Antibiotic Activity against a Large Collection of Respiratory Pathogens

por Landini, Giulia, Di Maggio, Tiziana, Sergio, Francesco, Docquier, Jean-Denis, Rossolini, Gian Maria, Pallecchi, Lucia
Publicado 2016

The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas

por Ardino, Claudia, Sannio, Filomena, Pasero, Carolina, Botta, Lorenzo, Dreassi, Elena, Docquier, Jean-Denis, D’Agostino, Ilaria
Publicado 2022

Isonitrile-Based Multicomponent Synthesis of β-Amino Boronic Acids as β-Lactamase Inhibitors

por Bassini, Emanuele, Gazzotti, Stefano, Sannio, Filomena, Lo Presti, Leonardo, Sgrignani, Jacopo, Docquier, Jean-Denis, Grazioso, Giovanni, Silvani, Alessandra
Publicado 2020

Efficient Inactivation of SARS-CoV-2 and Other RNA or DNA Viruses with Blue LED Light

por Terrosi, Chiara, Anichini, Gabriele, Docquier, Jean Denis, Gori Savellini, Gianni, Gandolfo, Claudia, Pavone, Francesco Saverio, Cusi, Maria Grazia
Publicado 2021

Optimization of a direct spectrophotometric method to investigate the kinetics and inhibition of sialidases

por Hayre, Jasvinder Kaur, Xu, Guogang, Borgianni, Luisa, Taylor, Garry L, Andrew, Peter W, Docquier, Jean-Denis, Oggioni, Marco R
Publicado 2012

Regulation of neuraminidase expression in Streptococcus pneumoniae

por Gualdi, Luciana, Hayre, Jasvinder Kaur, Gerlini, Alice, Bidossi, Alessandro, Colomba, Leonarda, Trappetti, Claudia, Pozzi, Gianni, Docquier, Jean-Denis, Andrew, Peter, Ricci, Susanna
Publicado 2012

Expanding the Repertoire of Carbapenem-Hydrolyzing Metallo-ß-Lactamases by Functional Metagenomic Analysis of Soil Microbiota

por Gudeta, Dereje D., Bortolaia, Valeria, Pollini, Simona, Docquier, Jean-Denis, Rossolini, Gian M., Amos, Gregory C. A., Wellington, Elizabeth M. H., Guardabassi, Luca
Publicado 2016

Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships

por Fantacuzzi, Marialuigia, D’Agostino, Ilaria, Carradori, Simone, Liguori, Francesco, Carta, Fabrizio, Agamennone, Mariangela, Angeli, Andrea, Sannio, Filomena, Docquier, Jean-Denis, Capasso, Clemente, Supuran, Claudiu T.
Publicado 2023

Discovering NDM-1 inhibitors using molecular substructure embeddings representations

por Papastergiou, Thomas, Azé, Jérôme, Bringay, Sandra, Louet, Maxime, Poncelet, Pascal, Rosales-Hurtado, Miyanou, Vo-Hoang, Yen, Licznar-Fajardo, Patricia, Docquier, Jean-Denis, Gavara, Laurent
Publicado 2023

Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) Superfamily

por Iannelli, Francesco, Santoro, Francesco, Santagati, Maria, Docquier, Jean-Denis, Lazzeri, Elisa, Pastore, Gabiria, Cassone, Marco, Oggioni, Marco R., Rossolini, Gian M., Stefani, Stefania, Pozzi, Gianni
Publicado 2018

Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109(T)

por Martinet, Loïc, Naômé, Aymeric, Rezende, Lucas C. D., Tellatin, Déborah, Pignon, Bernard, Docquier, Jean-Denis, Sannio, Filomena, Baiwir, Dominique, Mazzucchelli, Gabriel, Frédérich, Michel, Rigali, Sébastien
Publicado 2023

A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiot...

por Delavy, Margot, Burdet, Charles, Sertour, Natacha, Devente, Savannah, Docquier, Jean-Denis, Grall, Nathalie, Volant, Stevenn, Ghozlane, Amine, Duval, Xavier, Mentré, France, d’Enfert, Christophe, Bougnoux, Marie-Elisabeth
Publicado 2022

Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant Acinetobacter baumannii

por Sannio, Filomena, Brizzi, Antonella, Del Prete, Rosita, Avigliano, Marialuce, Simone, Tiziana, Pagli, Carlotta, Ferraro, Teresa, De Luca, Filomena, Paolino, Marco, Corelli, Federico, Mugnaini, Claudia, Docquier, Jean-Denis
Publicado 2022

Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases

por Spyrakis, Francesca, Santucci, Matteo, Maso, Lorenzo, Cross, Simon, Gianquinto, Eleonora, Sannio, Filomena, Verdirosa, Federica, De Luca, Filomena, Docquier, Jean-Denis, Cendron, Laura, Tondi, Donatella, Venturelli, Alberto, Cruciani, Gabriele, Costi, Maria Paola
Publicado 2020

Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases

por Santucci, Matteo, Spyrakis, Francesca, Cross, Simon, Quotadamo, Antonio, Farina, Davide, Tondi, Donatella, De Luca, Filomena, Docquier, Jean-Denis, Prieto, Ana Isabel, Ibacache, Claudia, Blázquez, Jesús, Venturelli, Alberto, Cruciani, Gabriele, Costi, Maria Paola
Publicado 2017

4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition

por Gavara, Laurent, Verdirosa, Federica, Legru, Alice, Mercuri, Paola Sandra, Nauton, Lionel, Sevaille, Laurent, Feller, Georges, Berthomieu, Dorothée, Sannio, Filomena, Marcoccia, Francesca, Tanfoni, Silvia, De Luca, Filomena, Gresh, Nohad, Galleni, Moreno, Docquier, Jean-Denis, Hernandez, Jean-François
Publicado 2020

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

por Everett, Martin J., Davies, David T., Leiris, Simon, Sprynski, Nicolas, Llanos, Agustina, Castandet, Jérôme M., Lozano, Clarisse, LaRock, Christopher N., LaRock, Doris L., Corsica, Giuseppina, Docquier, Jean-Denis, Pallin, Thomas D., Cridland, Andrew, Blench, Toby, Zalacain, Magdalena, Lemonnier, Marc
Publicado 2023

Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

por Liu, Bin, Trout, Robert E. Lee, Chu, Guo-Hua, McGarry, Daniel, Jackson, Randy W., Hamrick, Jodie C., Daigle, Denis M., Cusick, Susan M., Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Docquier, Jean-Denis, Weiss, William J., Pevear, Daniel C., Xerri, Luigi, Burns, Christopher J.
Publicado 2019