Pyrene conjugation and spectroscopic analysis of hydroxypropyl methylcellulose compounds successfully demonstrated a local dielectric difference associated with in vivo anti-prion...

por Teruya, Kenta, Oguma, Ayumi, Nishizawa, Keiko, Kamitakahara, Hiroshi, Doh-ura, Katsumi
Publicado 2017

Combining autophagy stimulators and cellulose ethers for therapy against prion disease

por Abdulrahman, Basant A., Tahir, Waqas, Doh-Ura, Katsumi, Gilch, Sabine, Schatzl, Hermann M.
Publicado 2019

A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents

por Teruya, Kenta, Oguma, Ayumi, Nishizawa, Keiko, Kawata, Maki, Sakasegawa, Yuji, Kamitakahara, Hiroshi, Doh-ura, Katsumi
Publicado 2016

Anti-prion activity found in beetle grub hemolymph of Trypoxylus dichotomus septentrionalis

por Hamanaka, Taichi, Nishizawa, Keiko, Sakasegawa, Yuji, Kurahashi, Hiroshi, Oguma, Ayumi, Teruya, Kenta, Doh-ura, Katsumi
Publicado 2015

Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression

por Hannaoui, Samia, Arifin, Maria Immaculata, Chang, Sheng Chun, Yu, Jie, Gopalakrishnan, Preetha, Doh‐ura, Katsumi, Schatzl, Hermann M., Gilch, Sabine
Publicado 2019

Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer’s disease

por Ali, Tahir, Klein, Antonia N., McDonald, Keegan, Johansson, Lovisa, Mukherjee, Priyanka Ganguli, Hallbeck, Martin, Doh-ura, Katsumi, Schatzl, Hermann M., Gilch, Sabine
Publicado 2023

Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics

por Ding, Mingxuan, Teruya, Kenta, Zhang, Weiguanliu, Lee, Hae Weon, Yuan, Jue, Oguma, Ayumi, Foutz, Aaron, Camacho, Manuel V., Mitchell, Marcus, Greenlee, Justin J., Kong, Qingzhong, Doh-ura, Katsumi, Cui, Li, Zou, Wen-Quan
Publicado 2021

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

por Minikel, Eric Vallabh, Zhao, Hien T, Le, Jason, O’Moore, Jill, Pitstick, Rose, Graffam, Samantha, Carlson, George A, Kavanaugh, Michael P, Kriz, Jasna, Kim, Jae Beom, Ma, Jiyan, Wille, Holger, Aiken, Judd, McKenzie, Deborah, Doh-ura, Katsumi, Beck, Matthew, O’Keefe, Rhonda, Stathopoulos, Jacquelyn, Caron, Tyler, Schreiber, Stuart L, Carroll, Jeffrey B, Kordasiewicz, Holly B, Cabin, Deborah E, Vallabh, Sonia M
Publicado 2020