Immunotherapy for Esophageal Squamous Cell Carcinoma

por Kojima, Takashi, Doi, Toshihiko
Publicado 2017

Current status of and future prospects for the treatment of unresectable or metastatic gastrointestinal stromal tumours

por Naito, Yoichi, Nishida, Toshirou, Doi, Toshihiko
Publicado 2023

Cost-effectiveness of trifluridine/tipiracil against nivolumab for heavily pretreated metastatic gastric cancer in Japan

por Takushima, Yusuke, Igarashi, Ataru, Yoshihara, Hiroshi, Shitara, Kohei, Doi, Toshihiko
Publicado 2021

Phase I study of olaratumab in Japanese patients with advanced solid tumors

por Doi, Toshihiko, Ma, Yan, Dontabhaktuni, Aruna, Nippgen, Cornelia, Nippgen, Johannes, Ohtsu, Atsushi
Publicado 2014

Phase I study of single‐agent ribociclib in Japanese patients with advanced solid tumors

por Doi, Toshihiko, Hewes, Becker, Kakizume, Tomoyuki, Tajima, Takeshi, Ishikawa, Norifumi, Yamada, Yasuhide
Publicado 2017

Phase I dose-escalation study of the safety, tolerability, and pharmacokinetics of aflibercept in combination with S-1 in Japanese patients with advanced solid malignancies

por Doi, Toshihiko, Boku, Narikazu, Onozawa, Yusuke, Takahashi, Keishiro, Kawaguchi, Osamu, Ohtsu, Atsushi
Publicado 2020

A phase 1 trial of xentuzumab, an IGF‐neutralizing antibody, in Japanese patients with advanced solid tumors

por Doi, Toshihiko, Kuboki, Yasutoshi, Naito, Yoichi, Ishida, Masahiro, Tanaka, Tetsuya, Takeuchi, Yoshito
Publicado 2022

Safety and efficacy of radium-223 dichloride in Japanese patients with castration-resistant prostate cancer and bone metastases

por Uemura, Hiroji, Uemura, Hirotsugu, Matsubara, Nobuaki, Kinuya, Seigo, Hosono, Makoto, Yajima, Yoko, Doi, Toshihiko
Publicado 2017

Phase I study of TAS-115, a novel oral multi-kinase inhibitor, in patients with advanced solid tumors

por Doi, Toshihiko, Matsubara, Nobuaki, Kawai, Akira, Naka, Norifumi, Takahashi, Shunji, Uemura, Hiroji, Yamamoto, Noboru
Publicado 2019

A phase 1 study of crenigacestat (LY3039478), the Notch inhibitor, in Japanese patients with advanced solid tumors

por Doi, Toshihiko, Tajimi, Masaomi, Mori, Joji, Asou, Hiroya, Inoue, Koichi, Benhadji, Karim A., Naito, Yoichi
Publicado 2020

Phase I Clinical and Pharmacokinetic Study of RAD001 (Everolimus) Administered Daily to Japanese Patients with Advanced Solid Tumors

por Okamoto, Isamu, Doi, Toshihiko, Ohtsu, Atsushi, Miyazaki, Masaki, Tsuya, Asuka, Kurei, Katsutoshi, Kobayashi, Ken, Nakagawa, Kazuhiko
Publicado 2010

Phase I Study of the Bifunctional Fusion Protein Bintrafusp Alfa in Asian Patients with Advanced Solid Tumors, Including a Hepatocellular Carcinoma Safety‐Assessment Cohort

por Doi, Toshihiko, Fujiwara, Yutaka, Koyama, Takafumi, Ikeda, Masafumi, Helwig, Christoph, Watanabe, Morihiro, Vugmeyster, Yulia, Kudo, Masatoshi
Publicado 2020

Phase 1 study of trebananib (AMG 386), an angiogenesis targeting angiopoietin-1/2 antagonist, in Japanese patients with advanced solid tumors

por Doi, Toshihiko, Ohtsu, Atsushi, Fuse, Nozomu, Yoshino, Takayuki, Tahara, Makoto, Shibayama, Kazuhiro, Takubo, Takatoshi, Weinreich, David M.
Publicado 2012

Phase 1 dose-escalation study of a novel oral PI3K/mTOR dual inhibitor, LY3023414, in patients with cancer

por Kondo, Shunsuke, Tajimi, Masaomi, Funai, Tomohiko, Inoue, Koichi, Asou, Hiroya, Ranka, Vinay Kumar, Wacheck, Volker, Doi, Toshihiko
Publicado 2020

Body weight loss as a prognostic and predictive factor in previously treated patients with metastatic gastric cancer: post hoc analyses of the randomized phase III TAGS trial

por Ghidini, Michele, Hochster, Howard, Doi, Toshihiko, Van Cutsem, Eric, Makris, Lukas, Takahashi, Osamu, Benhadji, Karim A., Mansoor, Wasat
Publicado 2023

Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer

por Doi, Toshihiko, Yoshino, Takayuki, Fuse, Nozomu, Boku, Narikazu, Yamazaki, Kentaro, Koizumi, Wasaburo, Shimada, Ken, Takinishi, Yasutaka, Ohtsu, Atsushi
Publicado 2015

Concordance between PIK3CA mutations in endoscopic biopsy and surgically resected specimens of esophageal squamous cell carcinoma

por Hatogai, Ken, Fujii, Satoshi, Kojima, Takashi, Daiko, Hiroyuki, Doi, Toshihiko, Ohtsu, Atsushi, Ochiai, Atsushi, Takiguchi, Yuichi, Yoshino, Takayuki
Publicado 2017

A Phase I study of intravenous PI3K inhibitor copanlisib in Japanese patients with advanced or refractory solid tumors

por Doi, Toshihiko, Fuse, Nozomu, Yoshino, Takayuki, Kojima, Takashi, Bando, Hideaki, Miyamoto, Hideaki, Kaneko, Masato, Osada, Motonobu, Ohtsu, Atsushi
Publicado 2016

Phase I trial of the MET inhibitor tepotinib in Japanese patients with solid tumors

por Shitara, Kohei, Yamazaki, Kentaro, Tsushima, Takahiro, Naito, Tateaki, Matsubara, Nobuaki, Watanabe, Morihiro, Sarholz, Barbara, Johne, Andreas, Doi, Toshihiko
Publicado 2020

Phase I study of ipatasertib as a single agent and in combination with abiraterone plus prednisolone in Japanese patients with advanced solid tumors

por Doi, Toshihiko, Fujiwara, Yutaka, Matsubara, Nobuaki, Tomomatsu, Junichi, Iwasa, Satoru, Tanaka, Akari, Endo-Tsukude, Chihiro, Nakagawa, Shintaro, Takahashi, Shunji
Publicado 2019