Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors

por Tomanová, Monika, Kozlanská, Karolína, Jorda, Radek, Jedinák, Lukáš, Havlíková, Tereza, Řezníčková, Eva, Peřina, Miroslav, Klener, Pavel, Dolníková, Alexandra, Cankař, Petr, Kryštof, Vladimír
Publicado 2022

MiR-140 leads to MRE11 downregulation and ameliorates oxaliplatin treatment and therapy response in colorectal cancer patients

por Horak, Josef, Dolnikova, Alexandra, Cumaogullari, Ozge, Cumova, Andrea, Navvabi, Nazila, Vodickova, Ludmila, Levy, Miroslav, Schneiderova, Michaela, Liska, Vaclav, Andera, Ladislav, Vodicka, Pavel, Opattova, Alena
Publicado 2022

Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas

por Jakša, Radek, Karolová, Jana, Svatoň, Michael, Kazantsev, Dmitry, Grajciarová, Martina, Pokorná, Eva, Tonar, Zbyněk, Klánová, Magdalena, Winkowska, Lucie, Maláriková, Diana, Vočková, Petra, Forsterová, Kristina, Renešová, Nicol, Dolníková, Alexandra, Nožičková, Kristýna, Dundr, Pavel, Froňková, Eva, Trněný, Marek, Klener, Pavel
Publicado 2022

Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping

por Břehová, Petra, Řezníčková, Eva, Škach, Kryštof, Jorda, Radek, Dejmek, Milan, Vojáčková, Veronika, Šála, Michal, Kovalová, Markéta, Dračínský, Martin, Dolníková, Alexandra, Strmeň, Timotej, Kinnertová, Monika, Chalupský, Karel, Dvořáková, Alexandra, Gucký, Tomáš, Mertlíková Kaiserová, Helena, Klener, Pavel, Nencka, Radim, Kryštof, Vladimír
Publicado 2023