Radiation Therapy in Management of Sporadic and Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors

por Kahn, Jenna, Gillespie, Andy, Tsokos, Maria, Ondos, John, Dombi, Eva, Camphausen, Kevin, Widemann, Brigitte C., Kaushal, Aradhana
Publicado 2014

Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1

por Nguyen, Rosa, Dombi, Eva, Widemann, Brigitte C, Solomon, Jeffrey, Fuensterer, Carsten, Kluwe, Lan, Friedman, Jan M, Mautner, Victor-Felix
Publicado 2012

Feasibility of magnetic resonance-guided high-intensity focused ultrasound treatment targeting distinct nodular lesions in neurofibromatosis type 1

por Tydings, Caitlin, Yarmolenko, Pavel, Bornhorst, Miriam, Dombi, Eva, Myseros, John, Keating, Robert, Bost, James, Sharma, Karun, Kim, AeRang
Publicado 2021

STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma

por Fletcher, Jonathan S., Springer, Mitchell G., Choi, Kwangmin, Jousma, Edwin, Rizvi, Tilat A., Dombi, Eva, Kim, Mi-Ok, Wu, Jianqiang, Ratner, Nancy
Publicado 2018

Doxorubicin pharmacokinetics and toxicity in patients with aggressive lymphoma and hepatic impairment

por Lai, Catherine, Cole, Diane E., Steinberg, Seth M., Lucas, Nicole, Dombi, Eva, Melani, Christopher, Roschewski, Mark, Balis, Frank, Widemann, Brigitte C., Wilson, Wyndham H.
Publicado 2022

Vinblastine/Methotrexate for Debilitating and Progressive Plexiform Neurofibroma in Children and Young Adults with Neurofibromatosis Type 1: A Phase 2 Study

por Kotch, Chelsea, Wagner, Kristina, Broad, J. Harris, Dombi, Eva, Minturn, Jane E., Phillips, Peter, Smith, Katherine, Li, Yimei, Jacobs, Ian N., Elden, Lisa M., Fisher, Michael J., Belasco, Jean
Publicado 2023

MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK

por Na, Youjin, Hall, Ashley, Choi, Kwangmin, Hu, Liang, Rose, Jonathan, Coover, Robert A., Miller, Adam, Hennigan, Robert F., Dombi, Eva, Kim, Mi-Ok, Subramanian, Subbaya, Ratner, Nancy, Wu, Jianqiang
Publicado 2020

A molecular basis for neurofibroma-associated skeletal manifestations in NF1

por Ma, Yun, Gross, Andrea, Dombi, Eva, Pemov, Alex, Choi, Kwangmin, Chaney, Katherine, Rhodes, Steven D., Angus, Steven P, Sciaky, Noah, Clapp, D Wade, Ratner, Nancy, Widemann, Brigitte C, Rios, Jonathan J, Elefteriou, Florent
Publicado 2020

NFB-17. MEK INHIBITOR BINIMETINIB SHOWS CLINICAL ACTIVITY IN CHILDREN WITH NEUROFIBROMATOSIS TYPE 1- ASSOCIATED PLEXIFORM NEUROFIBROMAS: A REPORT FROM PNOC AND THE NF CLINICAL TRIA...

por Mueller, Sabine, Reddy, Alyssa T, Dombi, Eva, Allen, Jeffrey, Packer, Roger, Clapp, Wade, Goldman, Stewart, Schorry, Elizabeth, Tonsgard, James, Blakeley, Jaishri, Ullrich, Nicole J, Gross, Andrea, Walsh, Karin, Thomas, Coretta, Edwards, Lloyd, Prados, Michael, Korf, Bruce, Fisher, Michael J
Publicado 2020

RUNX represses Pmp22 to drive neurofibromagenesis

por Hall, Ashley, Choi, Kwangmin, Liu, Wei, Rose, Jonathan, Zhao, Chuntao, Yu, Yanan, Na, Youjin, Cai, Yuqi, Coover, Robert A., Lin, Yi, Dombi, Eva, Kim, MiOk, Levanon, Ditsa, Groner, Yoram, Boscolo, Elisa, Pan, Dao, Liu, P. Paul, Lu, Q. Richard, Ratner, Nancy, Huang, Gang, Wu, Jianqiang
Publicado 2019

Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Beva...

por Widemann, Brigitte C., Lu, Yao, Reinke, Denise, Okuno, Scott H., Meyer, Christian F., Cote, Gregory M., Chugh, Rashmi, Milhem, Mohammed M., Hirbe, Angela C., Kim, AeRang, Turpin, Brian, Pressey, Joseph G., Dombi, Eva, Jayaprakash, Nalini, Helman, Lee J., Onwudiwe, Ndidi, Cichowski, Karen, Perentesis, John P.
Publicado 2019

NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults With NF1-Related Plexiform Neurofibrom...

por Weiss, Brian D., Wolters, Pamela L., Plotkin, Scott R., Widemann, Brigitte C., Tonsgard, James H., Blakeley, Jaishri, Allen, Jeffrey C., Schorry, Elizabeth, Korf, Bruce, Robison, Nathan J., Goldman, Stewart, Vinks, Alexander A., Emoto, Chie, Fukuda, Tsuyoshi, Robinson, Coretta T., Cutter, Gary, Edwards, Lloyd, Dombi, Eva, Ratner, Nancy, Packer, Roger, Fisher, Michael J.
Publicado 2021

Phase 1 open-label trial of intravenous administration of MVA-BN-brachyury-TRICOM vaccine in patients with advanced cancer

por DeMaria, Peter J, Lee-Wisdom, Katherine, Donahue, Renee N, Madan, Ravi A, Karzai, Fatima, Schwab, Angie, Palena, Claudia, Jochems, Caroline, Floudas, Charalampos, Strauss, Julius, Marté, Jennifer L, Redman, Jason Mark, Dombi, Eva, Widemann, Brigitte, Korchin, Borys, Adams, Tatiana, Pico-Navarro, Cesar, Heery, Christopher, Schlom, Jeffrey, Gulley, James L, Bilusic, Marijo
Publicado 2021

SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

por Higham, Christine S., Steinberg, Seth M., Dombi, Eva, Perry, Arie, Helman, Lee J., Schuetze, Scott M., Ludwig, Joseph A., Staddon, Arthur, Milhem, Mohammed M., Rushing, Daniel, Jones, Robin L., Livingston, Michael, Goldman, Stewart, Moertel, Christopher, Wagner, Lars, Janhofer, David, Annunziata, Christina M., Reinke, Denise, Long, Lauren, Viskochil, David, Baker, Larry, Widemann, Brigitte C.
Publicado 2017

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

por Isakson, Sara H., Rizzardi, Anthony E., Coutts, Alexander W., Carlson, Daniel F., Kirstein, Mark N., Fisher, James, Vitte, Jeremie, Williams, Kyle B., Pluhar, G. Elizabeth, Dahiya, Sonika, Widemann, Brigitte C., Dombi, Eva, Rizvi, Tilat, Ratner, Nancy, Messiaen, Ludwine, Stemmer-Rachamimov, Anat O., Fahrenkrug, Scott C., Gutmann, David H., Giovannini, Marco, Moertel, Christopher L., Largaespada, David A., Watson, Adrienne L.
Publicado 2018