Monitoring islet specific immune responses in type 1 diabetes clinical immunotherapy trials

por Arif, Sefina, Domingo-Vila, Clara, Pollock, Emily, Christakou, Eleni, Williams, Evangelia, Tree, Timothy I. M.
Publicado 2023

Evaluating T cell responses prior to the onset of type 1 diabetes

por Arif, Sefina, Yusuf, Norkhairin, Domingo‐Vila, Clara, Liu, Yuk‐Fun, Bingley, Polly J., Peakman, Mark
Publicado 2022

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects

por Arif, Sefina, Pujol-Autonell, Irma, Kamra, Yogesh, Williams, Evangelia, Yusuf, Norkhairin, Domingo-Vila, Clara, Shahrabi, Yasaman, Pollock, Emily, Khatri, Leena, Peakman, Mark, Tree, Timothy, Lorenc, Anna
Publicado 2021

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

por Johnson, Matthew B., Patel, Kashyap A., De Franco, Elisa, Hagopian, William, Killian, Michael, McDonald, Timothy J., Tree, Timothy I. M., Domingo-Vila, Clara, Hudson, Michelle, Hammersley, Suzanne, Dobbs, Rebecca, Ellard, Sian, Flanagan, Sarah E., Hattersley, Andrew T., Oram, Richard A.
Publicado 2020

Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer

por McKenzie, Duncan R., Graham, Rosalind, Lechmere, Thomas, Domingo-Vila, Clara, Alaguthurai, Thanussuyah, Arman, Celeste, Pollock, Emily, Gousis, Charalampos, Kakkassery, Helen, Carpenter, Esme, Kurshan, Ashwini, Vidler, Jennifer, Kulasekararaj, Austin, Patten, Piers, North, Bernard V., Tree, Timothy, Doores, Katie J., Hayday, Adrian C., Irshad, Sheeba
Publicado 2022

A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes

por Marwaha, Ashish K, Chow, Samuel, Pesenacker, Anne M, Cook, Laura, Sun, Annika, Long, S Alice, Yang, Jennie H M, Ward-Hartstonge, Kirsten A, Williams, Evangelia, Domingo-Vila, Clara, Halani, Khalif, Harris, Kristina M, Tree, Timothy I M, Levings, Megan K, Elliott, Thomas, Tan, Rusung, Dutz, Jan P
Publicado 2021

Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and lo...

por Christakoudi, Sofia, Runglall, Manohursingh, Mobillo, Paula, Tsui, Tjir-Li, Duff, Claire, Domingo-Vila, Clara, Kamra, Yogesh, Delaney, Florence, Montero, Rosa, Spiridou, Anastasia, Kassimatis, Theodoros, Phin-Kon, Sui, Tucker, Beatriz, Farmer, Christopher, Strom, Terry B., Lord, Graham M., Rebollo-Mesa, Irene, Stahl, Daniel, Sacks, Steven, Hernandez-Fuentes, Maria P., Chowdhury, Paramit
Publicado 2019

Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study

por Mahil, Satveer K, Bechman, Katie, Raharja, Antony, Domingo-Vila, Clara, Baudry, David, Brown, Matthew A, Cope, Andrew P, Dasandi, Tejus, Graham, Carl, Khan, Hataf, Lechmere, Thomas, Malim, Michael H, Meynell, Freya, Pollock, Emily, Sychowska, Kamila, Barker, Jonathan N, Norton, Sam, Galloway, James B, Doores, Katie J, Tree, Timothy, Smith, Catherine H
Publicado 2021

The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort study

por Mahil, Satveer K, Bechman, Katie, Raharja, Antony, Domingo-Vila, Clara, Baudry, David, Brown, Matthew A, Cope, Andrew P, Dasandi, Tejus, Graham, Carl, Lechmere, Thomas, Malim, Michael H, Meynell, Freya, Pollock, Emily, Seow, Jeffery, Sychowska, Kamila, Barker, Jonathan N, Norton, Sam, Galloway, James B, Doores, Katie J, Tree, Timothy I M, Smith, Catherine H
Publicado 2021

Humoral and cellular immunity to delayed second dose of SARS-CoV-2 BNT162b2 mRNA vaccination in patients with cancer

por McKenzie, Duncan R., Muñoz-Ruiz, Miguel, Monin, Leticia, Alaguthurai, Thanussuyah, Lechmere, Thomas, Abdul-Jawad, Sultan, Graham, Carl, Pollock, Emily, Graham, Rosalind, Sychowska, Kamila, Seow, Jeffrey, Tremain, Catherine, Gousis, Charalampos, Domingo-Vila, Clara, Cooper, Jack, Vidler, Jennifer, Owczarczyk, Kasia, Swampillai, Angela, Kristeleit, Hartmut, Malim, Michael H., Fields, Paul, Patten, Piers E.M., Papa, Sophie, North, Bernard V., Tree, Timothy, Doores, Katie J., Hayday, Adrian C., Irshad, Sheeba
Publicado 2021

Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study

por Monin, Leticia, Laing, Adam G, Muñoz-Ruiz, Miguel, McKenzie, Duncan R, del Molino del Barrio, Irene, Alaguthurai, Thanussuyah, Domingo-Vila, Clara, Hayday, Thomas S, Graham, Carl, Seow, Jeffrey, Abdul-Jawad, Sultan, Kamdar, Shraddha, Harvey-Jones, Elizabeth, Graham, Rosalind, Cooper, Jack, Khan, Muhammad, Vidler, Jennifer, Kakkassery, Helen, Sinha, Shubhankar, Davis, Richard, Dupont, Liane, Francos Quijorna, Isaac, O'Brien-Gore, Charlotte, Lee, Puay Ling, Eum, Josephine, Conde Poole, Maria, Joseph, Magdalene, Davies, Daniel, Wu, Yin, Swampillai, Angela, North, Bernard V, Montes, Ana, Harries, Mark, Rigg, Anne, Spicer, James, Malim, Michael H, Fields, Paul, Patten, Piers, Di Rosa, Francesca, Papa, Sophie, Tree, Timothy, Doores, Katie J, Hayday, Adrian C, Irshad, Sheeba
Publicado 2021