Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1(G93A) mouse model of ALS

por Dominguez, Sara L., Earr, Timothy, Dourado, Michelle, Ngu, Hai, Meilandt, William J., Hanson, Jesse E.
Publicado 2020

EGFR Inhibitor Erlotinib Delays Disease Progression but Does Not Extend Survival in the SOD1 Mouse Model of ALS

por Le Pichon, Claire E., Dominguez, Sara L., Solanoy, Hilda, Ngu, Hai, Lewin-Koh, Nicholas, Chen, Mark, Eastham-Anderson, Jeffrey, Watts, Ryan, Scearce-Levie, Kimberly
Publicado 2013

Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice

por Dominguez, Sara L., Hegde, Ganapati V., Hanson, Jesse E., Xiang, Hong, Mandikian, Danielle, Boswell, C. Andrew, Chiu, Cecilia, Wu, Yan, Tsai, Siao Ping, Fleck, Daniel, Weber, Martin, Ngu, Hai, Scearce-Levie, Kimberly, Jackson, Erica L.
Publicado 2018

Cognitive Deficits, Changes in Synaptic Function, and Brain Pathology in a Mouse Model of Normal Aging

por Weber, Martin, Wu, Tiffany, Hanson, Jesse E., Alam, Nazia M., Solanoy, Hilda, Ngu, Hai, Lauffer, Benjamin E., Lin, Han H., Dominguez, Sara L., Reeder, Jens, Tom, Jennifer, Steiner, Pascal, Foreman, Oded, Prusky, Glen T., Scearce-Levie, Kimberly
Publicado 2015

BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats

por Weber, Martin, Wu, Tiffany, Meilandt, William J., Dominguez, Sara L., Solanoy, Hilda O., Maloney, Janice A., Ngu, Hai, Baca, Miriam, Kung, Chung, Lima, Lisa, Earr, Timothy K., Fleck, Daniel, Shields, Shannon D., Forrest, William F., Foreman, Oded, Warming, Søren, Watts, Ryan J., Scearce-Levie, Kimberly
Publicado 2017

Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection

por Byrnes, Amy E., Dominguez, Sara L., Yen, Chun-Wan, Laufer, Benjamin I., Foreman, Oded, Reichelt, Mike, Lin, Han, Sagolla, Meredith, Hötzel, Kathy, Ngu, Hai, Soendergaard, Christoffer, Estevez, Alberto, Lin, Hsiu-Chao, Goyon, Alexandre, Bian, Juan, Lin, Jessica, Hinz, Flora I., Friedman, Brad A., Easton, Amy, Hoogenraad, Casper C.
Publicado 2023

TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models

por Dominguez, Sara L., Laufer, Benjamin I., Ghosh, Arundhati Sengupta, Li, Qingling, Ruggeri, Gaia, Emani, Maheswara Reddy, Phu, Lilian, Friedman, Brad A., Sandoval, Wendy, Rose, Christopher M., Ngu, Hai, Foreman, Oded, Reichelt, Mike, Juste, Yves, Lalehzadeh, Guita, Hansen, Dennis, Nymark, Helle, Mellal, Denia, Gylling, Helene, Kiełpiński, Łukasz J., Chih, Ben, Bingol, Baris, Hoogenraad, Casper C., Meilandt, William J., Easton, Amy
Publicado 2023