Conantokin-G Attenuates Detrimental Effects of NMDAR Hyperactivity in an Ischemic Rat Model of Stroke

por Balsara, Rashna, Dang, Alexander, Donahue, Deborah L., Snow, Tiffany, Castellino, Francis J.
Publicado 2015

Abrogation of Plasminogen Activator Inhibitor-1-Vitronectin Interaction Ameliorates Acute Kidney Injury in Murine Endotoxemia

por Gupta, Kamlesh K., Donahue, Deborah L., Sandoval-Cooper, Mayra J., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2015

Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation

por Gupta, Kamlesh K., Donahue, Deborah L., Sandoval-Cooper, Mayra J., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2017

Stable genetic integration of a red fluorescent protein in a virulent Group A Streptococcus strain

por Liang, Zhong, Carothers, Katelyn, Holmes, Adam, Donahue, Deborah, Lee, Shaun W., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2019

Mutations in the Control of Virulence Sensor Gene from Streptococcus pyogenes after Infection in Mice Lead to Clonal Bacterial Variants with Altered Gene Regulatory Activity and Vi...

por Mayfield, Jeffrey A., Liang, Zhong, Agrahari, Garima, Lee, Shaun W., Donahue, Deborah L., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2014

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with (18)F-FDG

por Balsara, Rashna D., Chapman, Sarah E., Sander, Ian M., Donahue, Deborah L., Liepert, Lucas, Castellino, Francis J., Leevy, W. Matthew
Publicado 2014

Neutralization of Streptolysin S-Dependent and Independent Inflammatory Cytokine IL-1β Activity Reduces Pathology During Early Group A Streptococcal Skin Infection

por Flaherty, Rebecca A., Donahue, Deborah L., Carothers, Katelyn E., Ross, Jessica N., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2018

Plasminogen Deficiency Significantly Reduces Vascular Wall Disease in a Murine Model of Type IIa Hypercholesterolemia

por Iwaki, Takayuki, Arakawa, Tomohiro, Sandoval-Cooper, Mayra J., Smith, Denise L., Donahue, Deborah, Ploplis, Victoria A., Umemura, Kazuo, Castellino, Francis J.
Publicado 2021

Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection

por Hammers, Daniel E., Donahue, Deborah L., Tucker, Zachary D., Ashfeld, Brandon L., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2022

The Streptococcal Protease SpeB Antagonizes the Biofilms of the Human Pathogen Staphylococcus aureus USA300 through Cleavage of the Staphylococcal SdrC Protein

por Carothers, Katelyn E., Liang, Zhong, Mayfield, Jeffrey, Donahue, Deborah L., Lee, Mijoon, Boggess, Bill, Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2020

A Key Role for the Urokinase Plasminogen Activator (uPA) in Invasive Group A Streptococcal Infection

por Sanderson-Smith, Martina L., Zhang, Yueling, Ly, Diane, Donahue, Deborah, Hollands, Andrew, Nizet, Victor, Ranson, Marie, Ploplis, Victoria A., Walker, Mark J., Castellino, Francis J.
Publicado 2013

Abnormal Whole Blood Thrombi in Humans with Inherited Platelet Receptor Defects

por Castellino, Francis J., Liang, Zhong, Davis, Patrick K., Balsara, Rashna D., Musunuru, Harsha, Donahue, Deborah L., Smith, Denise L., Sandoval-Cooper, Mayra J., Ploplis, Victoria A., Walsh, Mark
Publicado 2012

Group A Streptococcus-Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution

por Vu, Henry M., Hammers, Daniel E., Liang, Zhong, Nguyen, Gabrielle L., Benz, Mary E., Moran, Thomas E., Higashi, Dustin L., Park, Claudia J., Ayinuola, Yetunde A., Donahue, Deborah L., Flores-Mireles, Ana L., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2021

Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI

por Molina, Jonathan J., Kohler, Kurt N., Gager, Christopher, Andersen, Marissa J., Wongso, Ellsa, Lucas, Elizabeth R., Paik, Andrew, Xu, Wei, Donahue, Deborah L., Bergeron, Karla, Klim, Aleksandra, Caparon, Michael G., Hultgren, Scott J., Desai, Alana, Ploplis, Victoria A., Flick, Matthew J., Castellino, Francis J., Flores-Mireles, Ana L.
Publicado 2023