Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer

por Pal, Anupama, Donato, Nicholas J
Publicado 2014

Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells

por Potu, Harish, Kandarpa, Malathi, Peterson, Luke F., Donato, Nicholas J., Talpaz, Moshe
Publicado 2019

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma

por Potu, Harish, Kandarpa, Malathi, Peterson, Luke F., Durham, Alison, Donato, Nicholas J., Talpaz, Moshe
Publicado 2021

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway

por Potu, Harish, Peterson, Luke F., Pal, Anupama, Verhaegen, Monique, Cao, Juxiang, Talpaz, Moshe, Donato, Nicholas J.
Publicado 2014

Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response

por Perry, Jeffrey W., Ahmed, Mohammad, Chang, Kyeong-Ok, Donato, Nicholas J., Showalter, Hollis D., Wobus, Christiane E.
Publicado 2012

Small Molecule Deubiquitinase Inhibitors Promote Macrophage Anti-Infective Capacity

por Charbonneau, Marie-Eve, Gonzalez-Hernandez, Marta J., Showalter, Hollis D., Donato, Nicholas J., Wobus, Christiane E., O’Riordan, Mary X. D.
Publicado 2014

Pre-clinical evidence of PIM kinase inhibitor activity in BCR-ABL1 unmutated and mutated Philadelphia chromosome-positive (Ph+) leukemias

por Curi, Dany A., Beauchamp, Elspeth M., Blyth, Gavin T., Arslan, Ahmet Dirim, Donato, Nicholas J., Giles, Francis J., Altman, Jessica K., Platanias, Leonidas C.
Publicado 2015

Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

por Gonzalez-Hernandez, Marta J., Pal, Anupama, Gyan, Kofi E., Charbonneau, Marie-Eve, Showalter, Hollis D., Donato, Nicholas J., O'Riordan, Mary, Wobus, Christiane E.
Publicado 2014

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth()

por Pal, Anupama, Dziubinski, Michele, Di Magliano, Marina Pasca, Simeone, Diane M., Owens, Scott, Thomas, Dafydd, Peterson, Luke, Potu, Harish, Talpaz, Moshe, Donato, Nicholas J.
Publicado 2017

Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma

por Potu, Harish, Peterson, Luke F., Kandarpa, Malathi, Pal, Anupama, Sun, Hanshi, Durham, Alison, Harms, Paul W., Hollenhorst, Peter C., Eskiocak, Ugur, Talpaz, Moshe, Donato, Nicholas J.
Publicado 2017