A benzochalcone derivative synchronously induces apoptosis and ferroptosis in pancreatic cancer cells

por Guan, Xiaoqing, Zhao, Bing, Guan, Xiaodan, Dong, Jinyun, Ying, Jieer
Publicado 2023

Protein degradation technology: a strategic paradigm shift in drug discovery

por Li, Haobin, Dong, Jinyun, Cai, Maohua, Xu, Zhiyuan, Cheng, Xiang-Dong, Qin, Jiang-Jiang
Publicado 2021

Development of 2-arylbenzo[h]quinolone analogs as selective CYP1B1 inhibitors

por Dong, Jinyun, Wang, Zengtao, Meng, Qingqing, Zhang, Qijing, Huang, Guang, Cui, Jiahua, Li, Shaoshun
Publicado 2018

Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer

por Xu, Qianqian, Pan, Guangzhao, Wang, Zhonglan, Wang, Lingling, Tang, Yancheng, Dong, Jinyun, Qin, Jiang-Jiang
Publicado 2023

Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway

por Zhao, Jing, Shi, Yunfu, Ma, Yubo, Pan, Libin, Wang, Yanan, Yuan, Li, Dong, Jinyun, Ying, Jieer
Publicado 2023

PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

por Qi, Si-Min, Dong, Jinyun, Xu, Zhi-Yuan, Cheng, Xiang-Dong, Zhang, Wei-Dong, Qin, Jiang-Jiang
Publicado 2021

Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer

por Li, Haobin, Wang, Lingling, Cao, Fei, Yu, Dehua, Yang, Jing, Yu, Xuefei, Dong, Jinyun, Qin, Jiang-Jiang, Guan, Xiaoqing
Publicado 2022

Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3)

por Dong, Jinyun, Yang, Jing, Yu, Wenkai, Li, Haobin, Cai, Maohua, Xu, Jing-Li, Xu, Han-Dong, Shi, Yun-Fu, Guan, Xiaoqing, Cheng, Xiang‑Dong, Qin, Jiang‑Jiang
Publicado 2022

Polyphyllin B Suppresses Gastric Tumor Growth by Modulating Iron Metabolism and Inducing Ferroptosis

por Hu, Can, Zu, Dan, Xu, Jingli, Xu, Hangdong, Yuan, Li, Chen, Jiahui, Wei, Qin, Zhang, Yanqiang, Han, Jing, Lu, Tao, Dong, Jinyun, Qin, Jiang-Jiang, Xu, Zhiyuan, Cheng, Xiangdong
Publicado 2023

Integrative proteomic characterization of adenocarcinoma of esophagogastric junction

por Li, Shengli, Yuan, Li, Xu, Zhi-Yuan, Xu, Jing-Li, Chen, Gui-Ping, Guan, Xiaoqing, Pan, Guang-Zhao, Hu, Can, Dong, Jinyun, Du, Yi-An, Yang, Li-Tao, Ni, Mao-Wei, Jiang, Rui-Bin, Zhu, Xiu, Lv, Hang, Xu, Han-Dong, Zhang, Sheng-Jie, Qin, Jiang-Jiang, Cheng, Xiang-Dong
Publicado 2023