Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro

por Ramatsui, Lebogang, Dongola, Tendamudzimu Harmfree, Zininga, Tawanda, Multhoff, Gabriele, Shonhai, Addmore
Publicado 2023

Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting Plasmodium falciparum Hsp90

por Mafethe, Ofentse, Ntseane, Tlhalefo, Dongola, Tendamudzimu Harmfree, Shonhai, Addmore, Gumede, Njabulo Joyfull, Mokoena, Fortunate
Publicado 2023

Mutation of GGMP Repeat Segments of Plasmodium falciparum Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding

por Makumire, Stanley, Dongola, Tendamudzimu Harmfree, Chakafana, Graham, Tshikonwane, Lufuno, Chauke, Cecilia Tshikani, Maharaj, Tarushai, Zininga, Tawanda, Shonhai, Addmore
Publicado 2021

Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide

por Muthelo, Tshifhiwa, Mulaudzi, Vhahangwele, Netshishivhe, Munei, Dongola, Tendamudzimu Harmfree, Kok, Michelle, Makumire, Stanley, de Villiers, Marianne, Burger, Adélle, Zininga, Tawanda, Shonhai, Addmore
Publicado 2022