Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin

por Danzl, Nichole M., Donlin, Laura T., Alexandropoulos, Konstantina
Publicado 2010

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation

por Zhang, Fan, Mears, Joseph R., Shakib, Lorien, Beynor, Jessica I., Shanaj, Sara, Korsunsky, Ilya, Nathan, Aparna, Donlin, Laura T., Raychaudhuri, Soumya
Publicado 2020

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

por Zhang, Fan, Mears, Joseph R., Shakib, Lorien, Beynor, Jessica I., Shanaj, Sara, Korsunsky, Ilya, Nathan, Aparna, Donlin, Laura T., Raychaudhuri, Soumya
Publicado 2021

239. Sex Differences in Prosthetic Joint Infection

por Mironenko, Christine M, Kapadia, Milan, Donlin, Laura, Figgie, Mark, Carli, Alberto V, Henry, Michael, Goodman, Susan M, Miller, Andy O
Publicado 2021

Clinical and Histological Features of Prosthetic Joint Infections May Differ in Patients With Inflammatory Arthritis and Osteoarthritis

por Sculco, Peter, Kapadia, Milan, Moezinia, Carine J., Mannstadt, Insa, Miller, Andy O., Donlin, Laura, Henry, Michael, Russell, Linda, Figgie, Mark, Nocon, Allina, Pannellini, Tania, Goodman, Susan M.
Publicado 2023

Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis

por Smith, Melanie H., Gao, Vianne R., Periyakoil, Preethi K., Kochen, Alejandro, DiCarlo, Edward F., Goodman, Susan M., Norman, Thomas M., Donlin, Laura T., Leslie, Christina S., Rudensky, Alexander Y.
Publicado 2023

The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis

por Weinand, Kathryn, Sakaue, Saori, Nathan, Aparna, Jonsson, Anna Helena, Zhang, Fan, Watts, Gerald F. M., Zhu, Zhu, Rao, Deepak A., Anolik, Jennifer H., Brenner, Michael B., Donlin, Laura T., Wei, Kevin, Raychaudhuri, Soumya
Publicado 2023

Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation

por Stephenson, William, Donlin, Laura T., Butler, Andrew, Rozo, Cristina, Bracken, Bernadette, Rashidfarrokhi, Ali, Goodman, Susan M., Ivashkiv, Lionel B., Bykerk, Vivian P., Orange, Dana E., Darnell, Robert B., Swerdlow, Harold P., Satija, Rahul
Publicado 2018

In vitro responses to platelet-rich-plasma are associated with variable clinical outcomes in patients with knee osteoarthritis

por Zahir, Habib, Dehghani, Bijan, Yuan, Xiaoning, Chinenov, Yurii, Kim, Christine, Burge, Alissa, Bandhari, Reyna, Nemirov, Daniel, Fava, Patrick, Moley, Peter, Potter, Hollis, Nguyen, Joseph, Halpern, Brian, Donlin, Laura, Ivashkiv, Lionel, Rodeo, Scott, Otero, Miguel
Publicado 2021

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

por Meednu, Nida, Rangel-Moreno, Javier, Zhang, Fan, Escalera-Rivera, Katherine, Corsiero, Elisa, Prediletto, Edoardo, DiCarlo, Edward, Goodman, Susan, Donlin, Laura T., Raychauduri, Soumya, Bombardieri, Michele, Pitzalis, Costantino, Orange, Dana E., McDavid, Andrew, Anolik, Jennifer H.
Publicado 2022

Notch signaling drives synovial fibroblast identity and arthritis pathology

por Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L., Gao, Anqi, Watts, Gerald F. M., Major, Triin, Croft, Adam P., Watts, Jordan, Blazar, Philip, Lange, Jeffrey, Thornhill, Thomas, Filer, Andrew, Raza, Karim, Donlin, Laura T., Siebel, Christian W., Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Publicado 2020

Cytotoxic CD8(+) T cells target citrullinated antigens in rheumatoid arthritis

por Moon, Jae-Seung, Younis, Shady, Ramadoss, Nitya S., Iyer, Radhika, Sheth, Khushboo, Sharpe, Orr, Rao, Navin L., Becart, Stephane, Carman, Julie A., James, Eddie A., Buckner, Jane H., Deane, Kevin D., Holers, V. Michael, Goodman, Susan M., Donlin, Laura T., Davis, Mark M., Robinson, William H.
Publicado 2023

Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation

por Mehta, Bella, Goodman, Susan, DiCarlo, Edward, Jannat-Khah, Deanna, Gibbons, J. Alex B., Otero, Miguel, Donlin, Laura, Pannellini, Tania, Robinson, William H., Sculco, Peter, Figgie, Mark, Rodriguez, Jose, Kirschmann, Jessica M., Thompson, James, Slater, David, Frezza, Damon, Xu, Zhenxing, Wang, Fei, Orange, Dana E.
Publicado 2023

Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium

por Dunlap, Garrett, Wagner, Aaron, Meednu, Nida, Zhang, Fan, Jonsson, A. Helena, Wei, Kevin, Sakaue, Saori, Nathan, Aparna, Bykerk, Vivian P., Donlin, Laura T., Goodman, Susan M., Firestein, Gary S., Boyle, David L., Holers, V. Michael, Moreland, Larry W., Tabechian, Darren, Pitzalis, Costantino, Filer, Andrew, Raychaudhuri, Soumya, Brenner, Michael B., McDavid, Andrew, Rao, Deepak A., Anolik, Jennifer H.
Publicado 2023

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

por Mizoguchi, Fumitaka, Slowikowski, Kamil, Wei, Kevin, Marshall, Jennifer L., Rao, Deepak A., Chang, Sook Kyung, Nguyen, Hung N., Noss, Erika H., Turner, Jason D., Earp, Brandon E., Blazar, Philip E., Wright, John, Simmons, Barry P., Donlin, Laura T., Kalliolias, George D., Goodman, Susan M., Bykerk, Vivian P., Ivashkiv, Lionel B., Lederer, James A., Hacohen, Nir, Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Publicado 2018

Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution

por Kang, Joyce B., Shen, Amber Z., Sakaue, Saori, Luo, Yang, Gurajala, Saisriram, Nathan, Aparna, Rumker, Laurie, Aguiar, Vitor R. C., Valencia, Cristian, Lagattuta, Kaitlyn, Zhang, Fan, Jonsson, Anna Helena, Yazar, Seyhan, Alquicira-Hernandez, Jose, Khalili, Hamed, Ananthakrishnan, Ashwin N., Jagadeesh, Karthik, Dey, Kushal, Daly, Mark J., Xavier, Ramnik J., Donlin, Laura T., Anolik, Jennifer H., Powell, Joseph E., Rao, Deepak A., Brenner, Michael B., Gutierrez-Arcelus, Maria, Raychaudhuri, Soumya
Publicado 2023

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue

por Donlin, Laura T., Rao, Deepak A., Wei, Kevin, Slowikowski, Kamil, McGeachy, Mandy J., Turner, Jason D., Meednu, Nida, Mizoguchi, Fumitaka, Gutierrez-Arcelus, Maria, Lieb, David J., Keegan, Joshua, Muskat, Kaylin, Hillman, Joshua, Rozo, Cristina, Ricker, Edd, Eisenhaure, Thomas M., Li, Shuqiang, Browne, Edward P., Chicoine, Adam, Sutherby, Danielle, Noma, Akiko, Nusbaum, Chad, Kelly, Stephen, Pernis, Alessandra B., Ivashkiv, Lionel B., Goodman, Susan M., Robinson, William H., Utz, Paul J., Lederer, James A., Gravallese, Ellen M., Boyce, Brendan F., Hacohen, Nir, Pitzalis, Costantino, Gregersen, Peter K., Firestein, Gary S., Raychaudhuri, Soumya, Moreland, Larry W., Holers, V. Michael, Bykerk, Vivian P., Filer, Andrew, Boyle, David L., Brenner, Michael B., Anolik, Jennifer H.
Publicado 2018

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes

por Zhang, Fan, Jonsson, Anna Helena, Nathan, Aparna, Millard, Nghia, Curtis, Michelle, Xiao, Qian, Gutierrez-Arcelus, Maria, Apruzzese, William, Watts, Gerald F. M., Weisenfeld, Dana, Nayar, Saba, Rangel-Moreno, Javier, Meednu, Nida, Marks, Kathryne E., Mantel, Ian, Kang, Joyce B., Rumker, Laurie, Mears, Joseph, Slowikowski, Kamil, Weinand, Kathryn, Orange, Dana E., Geraldino-Pardilla, Laura, Deane, Kevin D., Tabechian, Darren, Ceponis, Arnoldas, Firestein, Gary S., Maybury, Mark, Sahbudin, Ilfita, Ben-Artzi, Ami, Mandelin, Arthur M., Nerviani, Alessandra, Lewis, Myles J., Rivellese, Felice, Pitzalis, Costantino, Hughes, Laura B., Horowitz, Diane, DiCarlo, Edward, Gravallese, Ellen M., Boyce, Brendan F., Moreland, Larry W., Goodman, Susan M., Perlman, Harris, Holers, V. Michael, Liao, Katherine P., Filer, Andrew, Bykerk, Vivian P., Wei, Kevin, Rao, Deepak A., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya
Publicado 2023

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

por Zhang, Fan, Wei, Kevin, Slowikowski, Kamil, Fonseka, Chamith Y., Rao, Deepak A., Kelly, Stephen, Goodman, Susan M., Tabechian, Darren, Hughes, Laura B., Salomon-Escoto, Karen, Watts, Gerald F. M., Jonsson, Anna H., Rangel-Moreno, Javier, Pellett, Nida M., Rozo, Cristina, Apruzzese, William, Eisenhaure, Thomas M., Lieb, David J., Boyle, David L., Mandelin, Arthur M., Boyce, Brendan F., DiCarlo, Edward, Gravallese, Ellen M., Gregersen, Peter K., Moreland, Larry, Firestein, Gary S., Hacohen, Nir, Nusbaum, Chad, Lederer, James A., Perlman, Harris, Pitzalis, Costantino, Filer, Andrew, Holers, V. Michael, Bykerk, Vivian P., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya, Albrecht, Jennifer, Bridges, S. Louis, Buckley, Christopher D., Buckner, Jane H., Dolan, James, Guthridge, Joel M., Gutierrez-Arcelus, Maria, Ivashkiv, Lionel B., James, Eddie A., James, Judith A., Keegan, Josh, Lee, Yvonne C., McGeachy, Mandy J., McNamara, Michael A., Mears, Joseph R., Mizoguchi, Fumitaka, Nguyen, Jennifer P., Noma, Akiko, Orange, Dana E., Rohani-Pichavant, Mina, Ritchlin, Christopher, Robinson, William H., Seshadri, Anupamaa, Sutherby, Danielle, Seifert, Jennifer, Turner, Jason D., Utz, Paul J.
Publicado 2019