Engineering the Dynamic Properties of Protein Networks through Sequence Variation

por Dooling, Lawrence J., Tirrell, David A.
Publicado 2016

Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture

por Ivanovska, Irena L., Tobin, Michael P., Bai, Tianyi, Dooling, Lawrence J., Discher, Dennis E.
Publicado 2023

Titrating CD47 by mismatch CRISPR-interference reveals incomplete repression can eliminate IgG-opsonized tumors but limits induction of antitumor IgG

por Hayes, Brandon H, Zhu, Hui, Andrechak, Jason C, Dooling, Lawrence J, Discher, Dennis E
Publicado 2023

CD47-SIRPα Checkpoint Disruption in Metastases Requires Tumor-Targeting Antibody for Molecular and Engineered Macrophage Therapies

por Andrechak, Jason C., Dooling, Lawrence J., Tobin, Michael P., Zhang, William, Hayes, Brandon H., Lee, Justine Y., Jin, Xiaoling, Irianto, Jerome, Discher, Dennis E.
Publicado 2022

Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate

por Pfeifer, Charlotte R., Tobin, Michael P., Cho, Sangkyun, Vashisth, Manasvita, Dooling, Lawrence J., Vazquez, Lizeth Lopez, Ricci-De Lucca, Emma G., Simon, Keiann T., Discher, Dennis E.
Publicado 2022

Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response

por Hayes, Brandon H., Wang, Mai, Zhu, Hui, Phan, Steven H., Andrechak, Jason C., Chang, Alexander H., Dooling, Lawrence J., Tobin, Michael P., Marchena, Tristan, Discher, Dennis E.
Publicado 2023

Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle

por Xia, Yuntao, Pfeifer, Charlotte R., Zhu, Kuangzheng, Irianto, Jerome, Liu, Dazhen, Pannell, Kalia, Chen, Emily J., Dooling, Lawrence J., Tobin, Michael P., Wang, Mai, Ivanovska, Irena L., Smith, Lucas R., Greenberg, Roger A., Discher, Dennis E.
Publicado 2019