Research attitudes in families of individuals with Down syndrome: importance for clinical trials

por Lott, Ira T., Kirby, Katharine A., Doran, Eric, Grill, Joshua D.
Publicado 2022

Cerebrovascular pathology in Down syndrome and Alzheimer disease

por Head, Elizabeth, Phelan, Michael J., Doran, Eric, Kim, Ronald C., Poon, Wayne W., Schmitt, Frederick A., Lott, Ira T.
Publicado 2017

Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

por Martini, Alessandra C., Helman, Alex M., McCarty, Katie L., Lott, Ira T., Doran, Eric, Schmitt, Frederick A., Head, Elizabeth
Publicado 2020

Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome

por Harp, Jordan P., Koehl, Lisa M., Pelt, Kathryn L. Van, Hom, Christy L., Doran, Eric, Head, Elizabeth, Lott, Ira T., Schmitt, Frederick A.
Publicado 2021

Increased plasma DYRK1A with aging may protect against neurodegenerative diseases

por Delabar, Jean M., Lagarde, Julien, Fructuoso, Marta, Mohammad, Ammara, Bottlaender, Michel, Doran, Eric, Lott, Ira, Rivals, Isabelle, Schmitt, Frederic A., Head, Elizabeth, Sarazin, Marie, Potier, Marie-Claude
Publicado 2023

A fibril-specific, conformation-dependent antibody recognizes a subset of Aβ plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain

por Sarsoza, Floyd, Saing, Tommy, Kayed, Rakez, Dahlin, Robert, Dick, Malcolm, Broadwater-Hollifield, Camille, Mobley, Scott, Lott, Ira, Doran, Eric, Gillen, Daniel, Anderson-Bergman, Clifford, Cribbs, David H., Glabe, Charles, Head, Elizabeth
Publicado 2009

Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome

por Henson, Rachel L., Doran, Eric, Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Lai, Florence, Lee, Joseph H., Rosas, H. Diana, Schupf, Nicole, Zaman, Shahid H., Lott, Ira T., Fagan, Anne M.
Publicado 2020

Brain amyloid and the transition to dementia in Down syndrome

por Keator, David B., Doran, Eric, Taylor, Lisa, Phelan, Michael J., Hom, Christy, Tseung, Katherine, van Erp, Theo G. M., Potkin, Steven G., Brickman, Adam M., Rosas, Diana H., Yassa, Michael A., Silverman, Wayne, Lott, Ira T.
Publicado 2020

Down syndrome: Distribution of brain amyloid in mild cognitive impairment

por Keator, David B., Phelan, Michael J., Taylor, Lisa, Doran, Eric, Krinsky‐McHale, Sharon, Price, Julie, Ballard, Erin E., Kreisl, William C., Hom, Christy, Nguyen, Dana, Pulsifer, Margaret, Lai, Florence, Rosas, Diana H., Brickman, Adam M., Schupf, Nicole, Yassa, Michael A., Silverman, Wayne, Lott, Ira T.
Publicado 2020

Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome

por Hartley, Sigan L., Fleming, Victoria, Piro-Gambetti, Brianna, Cohen, Annie, Ances, Beau M., Yassa, Michael A., Brickman, Adam M., Handen, Benjamin L., Head, Elizabeth, Mapstone, Mark, Christian, Bradley T., Lott, Ira T., Doran, Eric, Zaman, Shahid, Krinsky-McHale, Sharon, Schmitt, Fredrick A., Hom, Christy, Schupf, Nicole
Publicado 2022

Pathways linking pulse pressure to dementia in adults with Down syndrome

por Rizvi, Batool, Lao, Patrick J., Sathishkumar, Mithra, Taylor, Lisa, Queder, Nazek, McMillan, Liv, Edwards, Natalie, Keator, David B., Doran, Eric, Hom, Christy, Nguyen, Dana, Rosas, H. Diana, Lai, Florence, Schupf, Nicole, Gutierrez, Jose, Silverman, Wayne, Lott, Ira T., Mapstone, Mark, Wilcock, Donna M., Head, Elizabeth, Yassa, Michael A., Brickman, Adam M.
Publicado 2023

Joint‐label fusion brain atlases for dementia research in Down syndrome

por Queder, Nazek, Phelan, Michael J., Taylor, Lisa, Tustison, Nicholas, Doran, Eric, Hom, Christy, Nguyen, Dana, Lai, Florence, Pulsifer, Margaret, Price, Julie, Kreisl, William C., Rosas, Herminia D., Krinsky‐McHale, Sharon, Brickman, Adam M., Yassa, Michael A., Schupf, Nicole, Silverman, Wayne, Lott, Ira T., Head, Elizabeth, Mapstone, Mark, Keator, David B.
Publicado 2022

Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer’s Disease

por Miyoshi, Emily, Morabito, Samuel, Henningfield, Caden M., Rahimzadeh, Negin, Kiani Shabestari, Sepideh, Das, Sudeshna, Michael, Neethu, Reese, Fairlie, Shi, Zechuan, Cao, Zhenkun, Scarfone, Vanessa, Arreola, Miguel A., Lu, Jackie, Wright, Sierra, Silva, Justine, Leavy, Kelsey, Lott, Ira T., Doran, Eric, Yong, William H., Shahin, Saba, Perez-Rosendahl, Mari, Head, Elizabeth, Green, Kim N., Swarup, Vivek
Publicado 2023

Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer’s Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-...

por Hendrix, James A., Airey, David C., Britton, Angela, Burke, Anna D., Capone, George T., Chavez, Ronelyn, Chen, Jacqueline, Chicoine, Brian, Costa, Alberto C. S., Dage, Jeffrey L., Doran, Eric, Esbensen, Anna, Evans, Casey L., Faber, Kelley M., Foroud, Tatiana M., Hart, Sarah, Haugen, Kelsey, Head, Elizabeth, Hendrix, Suzanne, Hillerstrom, Hampus, Kishnani, Priya S., Krell, Kavita, Ledesma, Duvia Lara, Lai, Florence, Lott, Ira, Ochoa-Lubinoff, Cesar, Mason, Jennifer, Nicodemus-Johnson, Jessie, Proctor, Nicholas Kyle, Pulsifer, Margaret B., Revta, Carolyn, Rosas, H. Diana, Rosser, Tracie C., Santoro, Stephanie, Schafer, Kim, Scheidemantel, Thomas, Schmitt, Frederick, Skotko, Brian G., Stasko, Melissa R., Talboy, Amy, Torres, Amy, Wilmes, Kristi, Woodward, Jason, Zimmer, Jennifer A., Feldman, Howard H., Mobley, William
Publicado 2021