Multi-gene panel testing and association analysis in Cypriot breast cancer cases and controls

por Zanti, Maria, Loizidou, Maria A., O’Mahony, Denise G., Dorling, Leila, Dennis, Joe, Devilee, Peter, Easton, Douglas F., Panayiotidis, Mihalis I., Hadjisavvas, Andreas, Michailidou, Kyriaki
Publicado 2023

A nested cohort study of 6,248 early breast cancer patients treated in neoadjuvant and adjuvant chemotherapy trials investigating the prognostic value of chemotherapy-related toxic...

por Abraham, Jean E., Hiller, Louise, Dorling, Leila, Vallier, Anne-Laure, Dunn, Janet, Bowden, Sarah, Ingle, Susan, Jones, Linda, Hardy, Richard, Twelves, Christopher, Poole, Christopher J., Pharoah, Paul D P, Caldas, Carlos, Earl, Helena M.
Publicado 2015

Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study

por Yang, Xin, Eriksson, Mikael, Czene, Kamila, Lee, Andrew, Leslie, Goska, Lush, Michael, Wang, Jean, Dennis, Joe, Dorling, Leila, Carvalho, Sara, Mavaddat, Nasim, Simard, Jacques, Schmidt, Marjanka K, Easton, Douglas F, Hall, Per, Antoniou, Antonis C
Publicado 2022

The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study

por Dorling, Leila, Kar, Siddhartha, Michailidou, Kyriaki, Hiller, Louise, Vallier, Anne-Laure, Ingle, Susan, Hardy, Richard, Bowden, Sarah J., Dunn, Janet A., Twelves, Chris, Poole, Christopher J., Caldas, Carlos, Earl, Helena M., Pharoah, Paul D. P., Abraham, Jean E.
Publicado 2016

A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis

por Schack, Line M. H., Naderi, Elnaz, Fachal, Laura, Dorling, Leila, Luccarini, Craig, Dunning, Alison M., Ong, Enya H. W., Chua, Melvin L. K., Langendijk, Johannes A., Alizadeh, Behrooz Z., Overgaard, Jens, Eriksen, Jesper Grau, Andreassen, Christian Nicolaj, Alsner, Jan
Publicado 2022

Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity

por Ahmed, Mahbubl, Dorling, Leila, Kerns, Sarah, Fachal, Laura, Elliott, Rebecca, Partliament, Matt, Rosenstein, Barry S, Vega, Ana, Gómez-Caamaño, Antonio, Barnett, Gill, Dearnaley, David P, Hall, Emma, Sydes, Matt, Burnet, Neil, Pharoah, Paul D P, Eeles, Ros, West, Catharine M L
Publicado 2016

Splicing predictions, minigene analyses, and ACMG‐AMP clinical classification of 42 germline PALB2 splice‐site variants

por Valenzuela‐Palomo, Alberto, Bueno‐Martínez, Elena, Sanoguera‐Miralles, Lara, Lorca, Víctor, Fraile‐Bethencourt, Eugenia, Esteban‐Sánchez, Ada, Gómez‐Barrero, Susana, Carvalho, Sara, Allen, Jamie, García‐Álvarez, Alicia, Pérez‐Segura, Pedro, Dorling, Leila, Easton, Douglas F, Devilee, Peter, Vreeswijk, Maaike PG, de la Hoya, Miguel, Velasco, Eladio A
Publicado 2021

Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

por Li, Jingmei, Wen, Wei Xiong, Eklund, Martin, Kvist, Anders, Eriksson, Mikael, Christensen, Helene Nordahl, Torstensson, Astrid, Bajalica‐Lagercrantz, Svetlana, Dunning, Alison M., Decker, Brennan, Allen, Jamie, Luccarini, Craig, Pooley, Karen, Simard, Jacques, Dorling, Leila, Easton, Douglas F., Teo, Soo‐Hwang, Hall, Per, Borg, Åke, Grönberg, Henrik, Czene, Kamila
Publicado 2018

Segregation analysis of 17,425 population-based breast cancer families: Evidence for genetic susceptibility and risk prediction

por Li, Shuai, MacInnis, Robert J., Lee, Andrew, Nguyen-Dumont, Tu, Dorling, Leila, Carvalho, Sara, Dite, Gillian S., Shah, Mitul, Luccarini, Craig, Wang, Qin, Milne, Roger L., Jenkins, Mark A., Giles, Graham G., Dunning, Alison M., Pharoah, Paul D.P., Southey, Melissa C., Easton, Douglas F., Hopper, John L., Antoniou, Antonis C.
Publicado 2022

Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia

por Wen, Wei Xiong, Allen, Jamie, Lai, Kah Nyin, Mariapun, Shivaani, Hasan, Siti Norhidayu, Ng, Pei Sze, Lee, Daphne Shin-Chi, Lee, Sheau Yee, Yoon, Sook-Yee, Lim, Joanna, Lau, Shao Yan, Decker, Brennan, Pooley, Karen, Dorling, Leila, Luccarini, Craig, Baynes, Caroline, Conroy, Don M, Harrington, Patricia, Simard, Jacques, Yip, Cheng Har, Mohd Taib, Nur Aishah, Ho, Weang Kee, Antoniou, Antonis C, Dunning, Alison M, Easton, Douglas F, Teo, Soo Hwang
Publicado 2018

Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

por Kerns, Sarah L., Dorling, Leila, Fachal, Laura, Bentzen, Søren, Pharoah, Paul D.P., Barnes, Daniel R., Gómez-Caamaño, Antonio, Carballo, Ana M., Dearnaley, David P., Peleteiro, Paula, Gulliford, Sarah L., Hall, Emma, Michailidou, Kyriaki, Carracedo, Ángel, Sia, Michael, Stock, Richard, Stone, Nelson N., Sydes, Matthew R., Tyrer, Jonathan P., Ahmed, Shahana, Parliament, Matthew, Ostrer, Harry, Rosenstein, Barry S., Vega, Ana, Burnet, Neil G., Dunning, Alison M., Barnett, Gillian C., West, Catharine M.L.
Publicado 2016

Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy

por Kerns, Sarah L, Fachal, Laura, Dorling, Leila, Barnett, Gillian C, Baran, Andrea, Peterson, Derick R, Hollenberg, Michelle, Hao, Ke, Narzo, Antonio Di, Ahsen, Mehmet Eren, Pandey, Gaurav, Bentzen, Søren M, Janelsins, Michelle, Elliott, Rebecca M, Pharoah, Paul D P, Burnet, Neil G, Dearnaley, David P, Gulliford, Sarah L, Hall, Emma, Sydes, Matthew R, Aguado-Barrera, Miguel E, Gómez-Caamaño, Antonio, Carballo, Ana M, Peleteiro, Paula, Lobato-Busto, Ramón, Stock, Richard, Stone, Nelson N, Ostrer, Harry, Usmani, Nawaid, Singhal, Sandeep, Tsuji, Hiroshi, Imai, Takashi, Saito, Shiro, Eeles, Rosalind, DeRuyck, Kim, Parliament, Matthew, Dunning, Alison M, Vega, Ana, Rosenstein, Barry S, West, Catharine M L
Publicado 2019

The impact of coding germline variants on contralateral breast cancer risk and survival

por Morra, Anna, Mavaddat, Nasim, Muranen, Taru A., Ahearn, Thomas U., Allen, Jamie, Andrulis, Irene L., Auvinen, Päivi, Becher, Heiko, Behrens, Sabine, Blomqvist, Carl, Bojesen, Stig E., Bolla, Manjeet K., Brauch, Hiltrud, Camp, Nicola J., Carvalho, Sara, Castelao, Jose E., Cessna, Melissa H., Chang-Claude, Jenny, Chenevix-Trench, Georgia, Czene, Kamila, Decker, Brennan, Dennis, Joe, Dörk, Thilo, Dorling, Leila, Dunning, Alison M., Ekici, Arif B., Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine D., Flyger, Henrik, Gago-Dominguez, Manuela, García-Closas, Montserrat, Geurts-Giele, Willemina R.R., Giles, Graham G., Guénel, Pascal, Gündert, Melanie, Hahnen, Eric, Hall, Per, Hamann, Ute, Harrington, Patricia A., He, Wei, Heikkilä, Päivi, Hooning, Maartje J., Hoppe, Reiner, Howell, Anthony, Humphreys, Keith, Jakubowska, Anna, Jung, Audrey Y., Keeman, Renske, Kristensen, Vessela N., Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Mulligan, Anna Marie, Newman, William G., Park-Simon, Tjoung-Won, Peterlongo, Paolo, Pharoah, Paul D.P., Rhenius, Valerie, Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Spurdle, Amanda B., Tomlinson, Ian, Truong, Thérèse, van Veen, Elke M., Vreeswijk, Maaike P.G., Wang, Qin, Wendt, Camilla, Yang, Xiaohong R., Nevanlinna, Heli, Devilee, Peter, Easton, Douglas F., Schmidt, Marjanka K.
Publicado 2023

Large-scale meta–genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types

por Naderi, Elnaz, Aguado-Barrera, Miguel E, Schack, Line M H, Dorling, Leila, Rattay, Tim, Fachal, Laura, Summersgill, Holly, Martínez-Calvo, Laura, Welsh, Ceilidh, Dudding, Tom, Odding, Yasmin, Varela-Pazos, Ana, Jena, Rajesh, Thomson, David J, Steenbakkers, Roel J H M, Dennis, Joe, Lobato-Busto, Ramón, Alsner, Jan, Ness, Andy, Nutting, Chris, Gómez-Caamaño, Antonio, Eriksen, Jesper G, Thomas, Steve J, Bates, Amy M, Webb, Adam J, Choudhury, Ananya, Rosenstein, Barry S, Taboada-Valladares, Begona, Herskind, Carsten, Azria, David, Dearnaley, David P, de Ruysscher, Dirk, Sperk, Elena, Hall, Emma, Stobart, Hilary, Chang-Claude, Jenny, De Ruyck, Kim, Veldeman, Liv, Altabas, Manuel, De Santis, Maria Carmen, Farcy-Jacquet, Marie-Pierre, Veldwijk, Marlon R, Sydes, Matthew R, Parliament, Matthew, Usmani, Nawaid, Burnet, Neil G, Seibold, Petra, Symonds, R Paul, Elliott, Rebecca M, Bultijnck, Renée, Gutiérrez-Enríquez, Sara, Mollà, Meritxell, Gulliford, Sarah L, Green, Sheryl, Rancati, Tiziana, Reyes, Victoria, Carballo, Ana, Peleteiro, Paula, Sosa-Fajardo, Paloma, Parker, Chris, Fonteyne, Valérie, Johnson, Kerstie, Lambrecht, Maarten, Vanneste, Ben, Valdagni, Riccardo, Giraldo, Alexandra, Ramos, Mónica, Diergaarde, Brenda, Liu, Geoffrey, Leal, Suzanne M, Chua, Melvin L K, Pring, Miranda, Overgaard, Jens, Cascallar-Caneda, Luis M, Duprez, Fréderic, Talbot, Christopher J, Barnett, Gillian C, Dunning, Alison M, Vega, Ana, Andreassen, Christian Nicolaj, Langendijk, Johannes A, West, Catharine M L, Alizadeh, Behrooz Z, Kerns, Sarah L
Publicado 2023

Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

por Mavaddat, Nasim, Dorling, Leila, Carvalho, Sara, Allen, Jamie, González-Neira, Anna, Keeman, Renske, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Ahearn, Thomas U., Andrulis, Irene L., Beckmann, Matthias W., Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Briceno, Ignacio, Brüning, Thomas, Camp, Nicola J., Campbell, Archie, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chenevix-Trench, Georgia, Christiansen, Hans, Czene, Kamila, Dörk, Thilo, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine D., Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, Geisler, Jürgen, Giles, Graham G., Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Hartikainen, Jaana M., Hartman, Mikael, Hoppe, Reiner, Howell, Anthony, Jakubowska, Anna, Jung, Audrey, Khusnutdinova, Elza K., Kristensen, Vessela N., Li, Jingmei, Lim, Swee Ho, Lindblom, Annika, Loizidou, Maria A., Lophatananon, Artitaya, Lubiński, Jan, Madsen, Michael J., Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Mohd Taib, Nur Aishah, Morra, Anna, Muir, Kenneth, Obi, Nadia, Osorio, Ana, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Radice, Paolo, Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Sim, Xueling, Southey, Melissa C., Thorne, Heather, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Yip, Cheng Har, Spurdle, Amanda B., Vreeswijk, Maaike P.G., Dunning, Alison M., García-Closas, Montserrat, Pharoah, Paul D.P., Kvist, Anders, Muranen, Taru A., Nevanlinna, Heli, Teo, Soo Hwang, Devilee, Peter, Schmidt, Marjanka K., Easton, Douglas F.
Publicado 2022

Breast cancer risks associated with missense variants in breast cancer susceptibility genes

por Dorling, Leila, Carvalho, Sara, Allen, Jamie, Parsons, Michael T., Fortuno, Cristina, González-Neira, Anna, Heijl, Stephan M., Adank, Muriel A., Ahearn, Thomas U., Andrulis, Irene L., Auvinen, Päivi, Becher, Heiko, Beckmann, Matthias W., Behrens, Sabine, Bermisheva, Marina, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Bremer, Michael, Briceno, Ignacio, Camp, Nicola J., Campbell, Archie, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chenevix-Trench, Georgia, Collée, J. Margriet, Czene, Kamila, Dennis, Joe, Dörk, Thilo, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine, Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, Giles, Graham G., Glendon, Gord, Guénel, Pascal, Gündert, Melanie, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Harkness, Elaine F., Hartman, Mikael, Hogervorst, Frans B. L., Hollestelle, Antoinette, Hoppe, Reiner, Howell, Anthony, Jakubowska, Anna, Jung, Audrey, Khusnutdinova, Elza, Kim, Sung-Won, Ko, Yon-Dschun, Kristensen, Vessela N., Lakeman, Inge M. M., Li, Jingmei, Lindblom, Annika, Loizidou, Maria A., Lophatananon, Artitaya, Lubiński, Jan, Luccarini, Craig, Madsen, Michael J., Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Mohd Taib, Nur Aishah, Muir, Kenneth, Nevanlinna, Heli, Newman, William G., Oosterwijk, Jan C., Park, Sue K., Peterlongo, Paolo, Radice, Paolo, Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Sim, Xueling, Southey, Melissa C., Surowy, Harald, Suvanto, Maija, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, van Asperen, Christi J., Waltes, Regina, Wang, Qin, Yang, Xiaohong R., Pharoah, Paul D. P., Schmidt, Marjanka K., Benitez, Javier, Vroling, Bas, Dunning, Alison M., Teo, Soo Hwang, Kvist, Anders, de la Hoya, Miguel, Devilee, Peter, Spurdle, Amanda B., Vreeswijk, Maaike P. G., Easton, Douglas F.
Publicado 2022

Rare germline copy number variants (CNVs) and breast cancer risk

por Dennis, Joe, Tyrer, Jonathan P., Walker, Logan C., Michailidou, Kyriaki, Dorling, Leila, Bolla, Manjeet K., Wang, Qin, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Freeman, Laura E. Beane, Beckmann, Matthias W., Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bogdanova, Natalia V., Bojesen, Stig E., Brenner, Hermann, Castelao, Jose E., Chang-Claude, Jenny, Chenevix-Trench, Georgia, Clarke, Christine L., Collée, J. Margriet, Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Devilee, Peter, Dörk, Thilo, Dossus, Laure, Eliassen, A. Heather, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine, Fletcher, Olivia, Flyger, Henrik, Fritschi, Lin, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, Giles, Graham G., González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A., Hall, Per, Hollestelle, Antoinette, Hoppe, Reiner, Hopper, John L., Howell, Anthony, Jager, Agnes, Jakubowska, Anna, John, Esther M., Johnson, Nichola, Jones, Michael E., Jung, Audrey, Kaaks, Rudolf, Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M., Ko, Yon-Dschun, Kosma, Veli-Matti, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N., Kubelka-Sabit, Katerina, Kurian, Allison W., Lacey, James V., Lambrechts, Diether, Larson, Nicole L., Linet, Martha, Ogrodniczak, Alicja, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Muranen, Taru A., Murphy, Rachel A., Nevanlinna, Heli, Olson, Janet E., Olsson, Håkan, Park-Simon, Tjoung-Won, Perou, Charles M., Peterlongo, Paolo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Rennert, Gad, Saloustros, Emmanouil, Sandler, Dale P., Sawyer, Elinor J., Schmidt, Marjanka K., Schmutzler, Rita K., Shibli, Rana, Smeets, Ann, Soucy, Penny, Southey, Melissa C., Swerdlow, Anthony J., Tamimi, Rulla M., Taylor, Jack A., Teras, Lauren R., Terry, Mary Beth, Tomlinson, Ian, Troester, Melissa A., Truong, Thérèse, Vachon, Celine M., Wendt, Camilla, Winqvist, Robert, Wolk, Alicja, Yang, Xiaohong R., Zheng, Wei, Ziogas, Argyrios, Simard, Jacques, Dunning, Alison M., Pharoah, Paul D. P., Easton, Douglas F.
Publicado 2022