The Astronomical Pulse of Global Extinction Events

por Lewis, David F.V., Dorne, Jean-Lou C.M.
Publicado 2006

Derivation of a Human In Vivo Benchmark Dose for Perfluorooctanoic Acid From ToxCast In Vitro Concentration–Response Data Using a Computational Workflow for Probabilistic Quantitat...

por Loizou, George, McNally, Kevin, Dorne, Jean-Lou C. M., Hogg, Alex
Publicado 2021

Sourcing data on chemical properties and hazard data from the US-EPA CompTox Chemicals Dashboard: A practical guide for human risk assessment

por Williams, Antony J., Lambert, Jason C., Thayer, Kris, Dorne, Jean-Lou C.M.
Publicado 2021

Congeners-Specific Intestinal Absorption Of Microcystins In An In Vitro 3D Human Intestinal Epithelium: The Role Of Influx/Efflux Transporters

por Turco, Laura, Santori, Nicoletta, Buratti, Franca M., Dorne, Jean-Lou C. M., Testai, Emanuela
Publicado 2022

A Computational Understanding of Inter-Individual Variability in CYP2D6 Activity to Investigate the Impact of Missense Mutations on Ochratoxin A Metabolism

por Dorne, Jean Lou C. M., Cirlini, Martina, Louisse, Jochem, Pedroni, Lorenzo, Galaverna, Gianni, Dellafiora, Luca
Publicado 2022

A Computational Inter-Species Study on Safrole Phase I Metabolism-Dependent Bioactivation: A Mechanistic Insight into the Study of Possible Differences among Species

por Pedroni, Lorenzo, Louisse, Jochem, Punt, Ans, Dorne, Jean Lou C. M., Dall’Asta, Chiara, Dellafiora, Luca
Publicado 2023

Exploring Dimensionality Reduction Techniques for Deep Learning Driven QSAR Models of Mutagenicity

por Kalian, Alexander D., Benfenati, Emilio, Osborne, Olivia J., Gott, David, Potter, Claire, Dorne, Jean-Lou C. M., Guo, Miao, Hogstrand, Christer
Publicado 2023

Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics

por Kasteel, Emma E. J., Nijmeijer, Sandra M., Darney, Keyvin, Lautz, Leonie S., Dorne, Jean Lou C. M., Kramer, Nynke I., Westerink, Remco H. S.
Publicado 2020

The VEGA Tool to Check the Applicability Domain Gives Greater Confidence in the Prediction of In Silico Models

por Danieli, Alberto, Colombo, Erika, Raitano, Giuseppa, Lombardo, Anna, Roncaglioni, Alessandra, Manganaro, Alberto, Sommovigo, Alessio, Carnesecchi, Edoardo, Dorne, Jean-Lou C. M., Benfenati, Emilio
Publicado 2023

Cardiotoxicity of Chemical Substances: An Emerging Hazard Class

por Georgiadis, Nikolaos, Tsarouhas, Konstantinos, Dorne, Jean-Lou C. M., Kass, George E. N., Laspa, Petroula, Toutouzas, Konstantinos, Koulaouzidou, Elisabeth A., Kouretas, Dimitrios, Tsitsimpikou, Christina
Publicado 2022

What is considered cardiotoxicity of anthracyclines in animal studies

por Georgiadis, Nikolaos, Tsarouhas, Konstantinos, Rezaee, Ramin, Nepka, Haritini, Kass, George E.N., Dorne, Jean-Lou C.M., Stagos, Dimitrios, Toutouzas, Konstantinos, Spandidos, Demetrios A., Kouretas, Dimitrios, Tsitsimpikou, Christina
Publicado 2020

What is considered cardiotoxicity of anthracyclines in animal studies

por Georgiadis, Nikolaos, Tsarouhas, Konstantinos, Rezaee, Ramin, Nepka, Haritini, Kass, George E.N., Dorne, Jean-Lou C.M., Stagos, Dimitrios, Toutouzas, Konstantinos, Spandidos, Demetrios A., Kouretas, Dimitrios, Tsitsimpikou, Christina
Publicado 2020

Pilot survey reveals ophidiomycosis in dice snakes Natrix tessellata from Lake Garda, Italy

por Marini, Daniele, Di Nicola, Matteo R., Crocchianti, Veronica, Notomista, Tommaso, Iversen, Daniel, Coppari, Luca, Di Criscio, Michela, Brouard, Vanessa, Dorne, Jean-Lou C.M., Rüegg, Joëlle, Marenzoni, Maria Luisa
Publicado 2023

Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)

por Louisse, Jochem, Dellafiora, Luca, van den Heuvel, Jeroen J. M. W., Rijkers, Deborah, Leenders, Liz, Dorne, Jean-Lou C. M., Punt, Ans, Russel, Frans G. M., Koenderink, Jan B.
Publicado 2022

Risk Assessment of Combined Exposure to Multiple Chemicals at the European Food Safety Authority: Principles, Guidance Documents, Applications and Future Challenges

por Cattaneo, Irene, Kalian, Alexander D., Di Nicola, Matteo R., Dujardin, Bruno, Levorato, Sara, Mohimont, Luc, Nathanail, Alexis V., Carnessechi, Edoardo, Astuto, Maria Chiara, Tarazona, Jose V., Kass, George E. N., Liem, Antoine K. Djien, Robinson, Tobin, Manini, Paola, Hogstrand, Christer, Price, Paul S., Dorne, Jean Lou C. M.
Publicado 2023

Current EU research activities on combined exposure to multiple chemicals()

por Bopp, Stephanie K., Barouki, Robert, Brack, Werner, Dalla Costa, Silvia, Dorne, Jean-Lou C.M., Drakvik, Paula E., Faust, Michael, Karjalainen, Tuomo K., Kephalopoulos, Stylianos, van Klaveren, Jacob, Kolossa-Gehring, Marike, Kortenkamp, Andreas, Lebret, Erik, Lettieri, Teresa, Nørager, Sofie, Rüegg, Joëlle, Tarazona, Jose V., Trier, Xenia, van de Water, Bob, van Gils, Jos, Bergman, Åke
Publicado 2018

TKPlate 1.0: An Open‐access platform for toxicokinetic and toxicodynamic modelling of chemicals to implement new approach methodologies in chemical risk assessment

por Dorne, Jean Lou C. M., Cortiñas‐Abrahantes, José, Spyropoulos, Fotis, Darney, Keyvin, Lautz, Leonie, Louisse, Jochem, Kass, George E. N., Carnesecchi, Edoardo, Liem, A. K. Djien, Tarazona, José V., Billat, Pierre‐André, Beaudoin, Rémy, Zeman, Florence, Bodin, Cléo, Smith, Anthony, Nathanail, Alexis, Di Nicola, Matteo R., Kleiner, Juliane, Terron, Andrea, Parra‐Morte, Juan Manuel, Verloo, Didier, Robinson, Tobin
Publicado 2023

Application of Evidence-Based Methods to Construct Mechanism-Driven Chemical Assessment Frameworks

por Hoffmann, Sebastian, Aiassa, Elisa, Angrish, Michelle, Beausoleil, Claire, Bois, Frederic Y., Ciccolallo, Laura, Craig, Peter S., de Vries, Rob B. M., Dorne, Jean Lou C. M., Druwe, Ingrid L., Edwards, Stephen W., Eskes, Chantra, Georgiadis, Marios, Hartung, Thomas, Kienzler, Aude, Kristjansson, Elisabeth A., Lam, Juleen, Martino, Laura, Meek, Bette, Morgan, Rebecca L., Munoz-Guajardo, Irene, Noyes, Pamela D., Parmelli, Elena, Piersma, Aldert, Rooney, Andrew, Sena, Emily, Sullivan, Kristie, Tarazona, José, Terron, Andrea, Thayer, Kris, Turner, Jan, Verbeek, Jos, Verloo, Didier, Vinken, Mathieu, Watford, Sean, Whaley, Paul, Wikoff, Daniele, Willett, Kate, Tsaioun, Katya
Publicado 2022