Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery

por Ghose, Arup K., Herbertz, Torsten, Hudkins, Robert L., Dorsey, Bruce D., Mallamo, John P.
Publicado 2011

A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis

por Stump, Kristine L, Lu, Lily D, Dobrzanski, Pawel, Serdikoff, Cynthia, Gingrich, Diane E, Dugan, Ben J, Angeles, Thelma S, Albom, Mark S, Ator, Mark A, Dorsey, Bruce D, Ruggeri, Bruce A, Seavey, Matthew M
Publicado 2011

Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA

por Liu, Fei, Lee, Amy C. H., Guo, Fang, Kondratowicz, Andrew S., Micolochick Steuer, Holly M., Miller, Angela, Bailey, Lauren D., Wang, Xiaohe, Chen, Shuai, Kultgen, Steven G., Cuconati, Andrea, Cole, Andrew G., Gotchev, Dimitar, Dorsey, Bruce D., Rijnbrand, Rene, Lam, Angela M., Sofia, Michael J., Gao, Min
Publicado 2021

Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1

por Park, Jang-June, Thi, Emily P., Carpio, Victor H., Bi, Yingzhi, Cole, Andrew G., Dorsey, Bruce D., Fan, Kristi, Harasym, Troy, Iott, Christina L., Kadhim, Salam, Kim, Jin Hyang, Lee, Amy C. H., Nguyen, Duyan, Paratala, Bhavna S., Qiu, Ruiqing, White, Andre, Lakshminarasimhan, Damodharan, Leo, Christopher, Suto, Robert K., Rijnbrand, Rene, Tang, Sunny, Sofia, Michael J., Moore, Chris B.
Publicado 2021