xCT-Driven Expression of GPX4 Determines Sensitivity of Breast Cancer Cells to Ferroptosis Inducers

por Lee, Namgyu, Carlisle, Anne E., Peppers, Austin, Park, Sung Jin, Doshi, Mihir B., Spears, Meghan E., Kim, Dohoon
Publicado 2021

De novo sphingolipid biosynthesis necessitates detoxification in cancer cells

por Spears, Meghan E., Lee, Namgyu, Hwang, Sunyoung, Park, Sung Jin, Carlisle, Anne E., Li, Rui, Doshi, Mihir B., Armando, Aaron M., Gao, Jenny, Simin, Karl, Zhu, Lihua Julie, Greer, Paul L., Quehenberger, Oswald, Torres, Eduardo M., Kim, Dohoon
Publicado 2022

Selenium detoxification is required for cancer cell survival

por Carlisle, Anne E., Lee, Namgyu, Matthew-Onabanjo, Asia N., Spears, Meghan E., Park, Sung Jin, Youkana, Daniel, Doshi, Mihir B., Peppers, Austin, Li, Rui, Joseph, Alexander B., Smith, Miles, Simin, Karl, Zhu, Lihua Julie, Greer, Paul L., Shaw, Leslie M., Kim, Dohoon
Publicado 2020

Integrated genetic and pharmacologic interrogation of rare cancers

por Hong, Andrew L., Tseng, Yuen-Yi, Cowley, Glenn S., Jonas, Oliver, Cheah, Jaime H., Kynnap, Bryan D., Doshi, Mihir B., Oh, Coyin, Meyer, Stephanie C., Church, Alanna J., Gill, Shubhroz, Bielski, Craig M., Keskula, Paula, Imamovic, Alma, Howell, Sara, Kryukov, Gregory V., Clemons, Paul A., Tsherniak, Aviad, Vazquez, Francisca, Crompton, Brian D., Shamji, Alykhan F., Rodriguez-Galindo, Carlos, Janeway, Katherine A., Roberts, Charles W. M., Stegmaier, Kimberly, van Hummelen, Paul, Cima, Michael J., Langer, Robert S., Garraway, Levi A., Schreiber, Stuart L., Root, David E., Hahn, William C., Boehm, Jesse S.
Publicado 2016

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

por Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles WM, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C
Publicado 2019