AAA+ Machines of Protein Destruction in Mycobacteria

por Alhuwaider, Adnan Ali H., Dougan, David A.
Publicado 2017

Anti-adaptors use distinct modes of binding to inhibit the RssB-dependent turnover of RpoS (σ(S)) by ClpXP

por Micevski, Dimce, Zammit, Jessica E., Truscott, Kaye N., Dougan, David A.
Publicado 2015

LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins

por Bezawork-Geleta, Ayenachew, Brodie, Erica J., Dougan, David A., Truscott, Kaye N.
Publicado 2015

Perrault syndrome type 3 caused by diverse molecular defects in CLPP

por Brodie, Erica J., Zhan, Hanmiao, Saiyed, Tamanna, Truscott, Kaye N., Dougan, David A.
Publicado 2018

Molecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis

por Nagpal, Jyotsna, Paxman, Jason J., Zammit, Jessica E., Thomas, Adam A., Truscott, Kaye N., Heras, Begoña, Dougan, David A.
Publicado 2019

Insight into the RssB-Mediated Recognition and Delivery of σ(s) to the AAA+ Protease, ClpXP

por Micevski, Dimce, Zeth, Kornelius, Mulhern, Terrence D., Schuenemann, Verena J., Zammit, Jessica E., Truscott, Kaye N., Dougan, David A.
Publicado 2020

Polymerase delta-interacting protein 38 (PDIP38) modulates the stability and activity of the mitochondrial AAA+ protease CLPXP

por Strack, Philip R., Brodie, Erica J., Zhan, Hanmiao, Schuenemann, Verena J., Valente, Liz J., Saiyed, Tamanna, Lowth, Bradley R., Angley, Lauren M., Perugini, Matthew A., Zeth, Kornelius, Truscott, Kaye N., Dougan, David A.
Publicado 2020