A Novel High-Content Phenotypic Screen To Identify Inhibitors of Mitochondrial DNA Maintenance in Trypanosomes

por Miskinyte, Migla, Dawson, John C., Makda, Ashraff, Doughty-Shenton, Dahlia, Carragher, Neil O., Schnaufer, Achim
Publicado 2022

Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer

por Kitamura, Takanori, Doughty-Shenton, Dahlia, Cassetta, Luca, Fragkogianni, Stamatina, Brownlie, Demi, Kato, Yu, Carragher, Neil, Pollard, Jeffrey W.
Publicado 2018

Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β

por Brownlie, Demi, Doughty-Shenton, Dahlia, YH Soong, Daniel, Nixon, Colin, O Carragher, Neil, M Carlin, Leo, Kitamura, Takanori
Publicado 2021

Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor

por Drebert, Zuzanna, MacAskill, Mark, Doughty-Shenton, Dahlia, De Bosscher, Karolien, Bracke, Marc, Hadoke, Patrick W.F., Beck, Ilse M.
Publicado 2017

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

por De Simone, Alessio, Georgiou, Charis, Ioannidis, Harris, Gupta, Arun A., Juárez-Jiménez, Jordi, Doughty-Shenton, Dahlia, Blackburn, Elizabeth A., Wear, Martin A., Richards, Jonathan P., Barlow, Paul N., Carragher, Neil, Walkinshaw, Malcolm D., Hulme, Alison N., Michel, Julien
Publicado 2018