Whole-genome transcriptomic insights into protective molecular mechanisms in metabolically healthy obese African Americans

por Gaye, Amadou, Doumatey, Ayo P., Davis, Sharon K., Rotimi, Charles N., Gibbons, Gary H.
Publicado 2018

Mendelian randomization study reveals a causal relationship between adiponectin and LDL cholesterol in Africans

por Meeks, Karlijn A. C., Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Rotimi, Charles N.
Publicado 2022

Phenotypic variance explained by local ancestry in admixed African Americans

por Shriner, Daniel, Bentley, Amy R., Doumatey, Ayo P., Chen, Guanjie, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.
Publicado 2015

Gut Microbiome Profiles Are Associated With Type 2 Diabetes in Urban Africans

por Doumatey, Ayo P., Adeyemo, Adebowale, Zhou, Jie, Lei, Lin, Adebamowo, Sally N., Adebamowo, Clement, Rotimi, Charles N.
Publicado 2020

Time-to-event modeling of hypertension reveals the nonexistence of true controls

por Shriner, Daniel, Bentley, Amy R, Zhou, Jie, Ekoru, Kenneth, Doumatey, Ayo P, Chen, Guanjie, Adeyemo, Adebowale, Rotimi, Charles N
Publicado 2020

A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals

por Chen, Guanjie, Adeyemo, Adebowale, Zhou, Jie, Doumatey, Ayo P., Bentley, Amy R., Ekoru, Kenneth, Shriner, Daniel, Rotimi, Charles N.
Publicado 2021

Circulating MiR-374a-5p is a potential modulator of the inflammatory process in obesity

por Doumatey, Ayo P., He, William J., Gaye, Amadou, Lei, Lin, Zhou, Jie, Gibbons, Gary H., Adeyemo, Adebowale, Rotimi, Charles N.
Publicado 2018

An epigenome-wide association study of insulin resistance in African Americans

por Chilunga, Felix P., Meeks, Karlijn A. C., Henneman, Peter, Agyemang, Charles, Doumatey, Ayo P., Rotimi, Charles N., Adeyemo, Adebowale A.
Publicado 2022

Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensiti...

por Meeks, Karlijn A. C., Bentley, Amy R., Assimes, Themistocles L., Franceschini, Nora, Adeyemo, Adebowale A., Rotimi, Charles N., Doumatey, Ayo P.
Publicado 2023

Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes

por Chen, Guanjie, Shriner, Daniel, Zhang, Jianhua, Zhou, Jie, Adikaram, Poorni, Doumatey, Ayo P., Bentley, Amy R., Adeyemo, Adebowale, Rotimi, Charles N.
Publicado 2022

APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans

por Bentley, Amy R., Divers, Jasmin, Shriner, Daniel, Doumatey, Ayo P., Gutiérrez, Orlando M., Adeyemo, Adebowale A., Freedman, Barry I., Rotimi, Charles N.
Publicado 2015

Universal genome-wide association studies: Powerful joint ancestry and association testing

por Shriner, Daniel, Bentley, Amy R., Gouveia, Mateus H., Heuston, Elisabeth F., Doumatey, Ayo P., Chen, Guanjie, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.
Publicado 2023

Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans

por Shriner, Daniel, Kumkhaek, Chutima, Doumatey, Ayo P., Chen, Guanjie, Bentley, Amy R., Charles, Bashira A., Zhou, Jie, Adeyemo, Adebowale, Rodgers, Griffin P., Rotimi, Charles N.
Publicado 2015

Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits

por Meeks, Karlijn A. C., Bentley, Amy R., Gouveia, Mateus H., Chen, Guanjie, Zhou, Jie, Lei, Lin, Adeyemo, Adebowale A., Doumatey, Ayo P., Rotimi, Charles N.
Publicado 2021

Multiple Loci Associated with Renal Function in African Americans

por Shriner, Daniel, Herbert, Alan, Doumatey, Ayo P., Zhou, Jie, Huang, Hanxia, Erdos, Michael R., Chen, Guanjie, Gerry, Norman P., Christman, Michael F., Adeyemo, Adebowale, Rotimi, Charles N.
Publicado 2012

Transferability and Fine Mapping of genome-wide associated loci for lipids in African Americans

por Adeyemo, Adebowale, Bentley, Amy R, Meilleur, Katherine G, Doumatey, Ayo P, Chen, Guanjie, Zhou, Jie, Shriner, Daniel, Huang, Hanxia, Herbert, Alan, Gerry, Norman P, Christman, Michael F, Rotimi, Charles N
Publicado 2012

Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese

por Chen, Guanjie, Zhang, Zhenjian, Adebamowo, Sally N., Liu, Guozheng, Adeyemo, Adebowale, Zhou, Yanxun, Doumatey, Ayo P., Wang, Chuntao, Zhou, Jie, Yan, Wenqiang, Shriner, Daniel, Tekola-Ayele, Fasil, Bentley, Amy R., Jiang, Congqing, Rotimi, Charles N.
Publicado 2017

UGT1A1 is a major locus influencing bilirubin levels in African Americans

por Chen, Guanjie, Ramos, Edward, Adeyemo, Adebowale, Shriner, Daniel, Zhou, Jie, Doumatey, Ayo P, Huang, Hanxia, Erdos, Michael R, Gerry, Norman P, Herbert, Alan, Bentley, Amy R, Xu, Huichun, Charles, Bashira A, Christman, Michael F, Rotimi, Charles N
Publicado 2012

Gene-Based Sequencing Identifies Lipid-Influencing Variants with Ethnicity-Specific Effects in African Americans

por Bentley, Amy R., Chen, Guanjie, Shriner, Daniel, Doumatey, Ayo P., Zhou, Jie, Huang, Hanxia, Mullikin, James C., Blakesley, Robert W., Hansen, Nancy F., Bouffard, Gerard G., Cherukuri, Praveen F., Maskeri, Baishali, Young, Alice C., Adeyemo, Adebowale, Rotimi, Charles N.
Publicado 2014

Genome-wide association study of type 2 diabetes in Africa

por Chen, Ji, Sun, Meng, Adeyemo, Adebowale, Pirie, Fraser, Carstensen, Tommy, Pomilla, Cristina, Doumatey, Ayo P., Chen, Guanjie, Young, Elizabeth H., Sandhu, Manjinder, Morris, Andrew P., Barroso, Inês, McCarthy, Mark I., Mahajan, Anubha, Wheeler, Eleanor, Rotimi, Charles N., Motala, Ayesha A.
Publicado 2019