GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study

por Johansson, Maja, Månsson, Maria, Lins, Lars-Eric, Scharschmidt, Bruce, Doverskog, Magnus, Bäckström, Torbjörn
Publicado 2018

Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer’s Disease

por Philippens, Ingrid H., Ormel, Paul R., Baarends, Guus, Johansson, Maja, Remarque, Ed J., Doverskog, Magnus
Publicado 2016

Extra-Synaptic GABA(A) Receptor Potentiation and Neurosteroid-Induced Learning Deficits Are Inhibited by GR3027, a GABA(A) Modulating Steroid Antagonist

por Bengtsson, Sara K. S., Sjöstedt, Jessica, Malinina, Evgenya, Das, Roshni, Doverskog, Magnus, Johansson, Maja, Haage, David, Bäckström, Torbjörn
Publicado 2023

Baculovirus-mediated gene transfer and recombinant protein expression do not interfere with insulin dependent phosphorylation of PKB/Akt in human SHSY-5Y and C3A cells

por Andersson, Monica, Warolén, Malin, Nilsson, Joakim, Selander, Martin, Sterky, Catharina, Bergdahl, Katrin, Sörving, Christina, James, Stephen R, Doverskog, Magnus
Publicado 2007

GR3027 antagonizes GABA(A) receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy

por Johansson, Maja, Agusti, Ana, Llansola, Marta, Montoliu, Carmina, Strömberg, Jessica, Malinina, Evgenya, Ragagnin, Gianna, Doverskog, Magnus, Bäckström, Torbjörn, Felipo, Vicente
Publicado 2015

Golexanolone, a GABA(A) receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammatio...

por Mincheva, Gergana, Gimenez‐Garzo, Carla, Izquierdo‐Altarejos, Paula, Martinez‐Garcia, Mar, Doverskog, Magnus, Blackburn, Thomas P., Hällgren, Anneli, Bäckström, Torbjörn, Llansola, Marta, Felipo, Vicente
Publicado 2022

Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?

por Wetten, Aaron, Ogle, Laura, Mells, George, Hegade, Vinod S., Jopson, Laura, Corrigan, Margaret, Palmer, Jeremy, Johansson, Maja, Bäckström, Torbjörn, Doverskog, Magnus, Jones, David E. J., Dyson, Jessica K.
Publicado 2022