The Janus kinase 1/2 inhibitor baricitinib reduces biomarkers of joint destruction in moderate to severe rheumatoid arthritis

por Thudium, Christian S., Bay-Jensen, Anne C., Cahya, Suntara, Dow, Ernst R., Karsdal, Morten A., Koch, Alisa E., Zhang, Wenling, Benschop, Robert J.
Publicado 2020

Prediction and analysis of functional RNA structures within the integrative genomics viewer

por Rouse, Warren B, Andrews, Ryan J, Booher, Nicholas J, Wang, Jibo, Woodman, Michael E, Dow, Ernst R, Jessop, Theodore C, Moss, Walter N
Publicado 2022

Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus

por Dörner, Thomas, Tanaka, Yoshiya, Dow, Ernst R, Koch, Alisa E, Silk, Maria, Ross Terres, Jorge A, Sims, Jonathan T, Sun, Zhe, de la Torre, Inmaculada, Petri, Michelle
Publicado 2022

Evolutionary computation for discovery of composite transcription factor binding sites

por Fogel, Gary B., Porto, V. William, Varga, Gabor, Dow, Ernst R., Craven, Andrew M., Powers, David M., Harlow, Harry B., Su, Eric W., Onyia, Jude E., Su, Chen
Publicado 2008

A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus

por Li, Yupeng, Higgs, Richard E., Hoffman, Robert W., Dow, Ernst R., Liu, Xiong, Petri, Michelle, Wallace, Daniel J., Dörner, Thomas, Eastwood, Brian J., Miller, Bradley B., Liu, Yushi
Publicado 2019

Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple imm...

por Dörner, Thomas, Tanaka, Yoshiya, Petri, Michelle A, Smolen, Josef S, Wallace, Daniel J, Dow, Ernst R, Higgs, Richard E, Rocha, Guilherme, Crowe, Brenda, Benschop, Robert J, Byers, Nicole L, Silk, Maria E, de Bono, Stephanie, Fantini, Damiano, Hoffman, Robert W
Publicado 2020

Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab

por Hoffman, Robert W., Merrill, Joan T., Alarcón‐Riquelme, Marta M. E., Petri, Michelle, Dow, Ernst R., Nantz, Eric, Nisenbaum, Laura K., Schroeder, Krista M., Komocsar, Wendy J., Perumal, Narayanan B., Linnik, Matthew D., Airey, David C., Liu, Yushi, Rocha, Guilherme V., Higgs, Richard E.
Publicado 2017