ACE2 as a Therapeutic Target for COVID-19; Its Role in Infectious Processes and Regulation by Modulators of the RAAS System

por Michaud, Veronique, Deodhar, Malavika, Arwood, Meghan, Al Rihani, Sweilem B, Dow, Pamela, Turgeon, Jacques
Publicado 2020

Physiologically Based Pharmacokinetic Modeling to Assess the Impact of CYP2D6‐Mediated Drug‐Drug Interactions on Tramadol and O‐Desmethyltramadol Exposures via Allosteric and Compe...

por Long, Tao, Cristofoletti, Rodrigo, Cicali, Brian, Michaud, Veronique, Dow, Pamela, Turgeon, Jacques, Schmidt, Stephan
Publicado 2021

Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier Level

por Al Rihani, Sweilem B., Darakjian, Lucy I., Deodhar, Malavika, Dow, Pamela, Turgeon, Jacques, Michaud, Veronique
Publicado 2021

Risk Assessment of Drug‐Induced Long QT Syndrome for Some COVID‐19 Repurposed Drugs

por Michaud, Veronique, Dow, Pamela, Al Rihani, Sweilem B., Deodhar, Malavika, Arwood, Meghan, Cicali, Brian, Turgeon, Jacques
Publicado 2020

Risk of Adverse Drug Events Following the Virtual Addition of COVID-19 Repurposed Drugs to Drug Regimens of Frail Older Adults with Polypharmacy

por Al Rihani, Sweilem B., Smith, Matt K., Bikmetov, Ravil, Deodhar, Malavika, Dow, Pamela, Turgeon, Jacques, Michaud, Veronique
Publicado 2020

Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice

por Deodhar, Malavika, Al Rihani, Sweilem B, Arwood, Meghan J., Darakjian, Lucy, Dow, Pamela, Turgeon, Jacques, Michaud, Veronique
Publicado 2020

Adverse drug event risk assessment by the virtual addition of COVID‐19 repurposed drugs to Medicare and commercially insured patients’ drug regimens: A drug safety simulation study...

por Smith, Matt K., Bikmetov, Ravil, Al Rihani, Sweilem B., Deodhar, Malavika, Hafermann, Matthew, Dow, Pamela, Turgeon, Jacques, Michaud, Veronique
Publicado 2021

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models

por Al Rihani, Sweilem B., Deodhar, Malavika, Darakjian, Lucy I., Dow, Pamela, Smith, Matt K., Bikmetov, Ravil, Turgeon, Jacques, Michaud, Veronique
Publicado 2021

Use of Drug Claims Data and a Medication Risk Score to Assess the Impact of CYP2D6 Drug Interactions among Opioid Users on Healthcare Costs

por Michaud, Veronique, Bikmetov, Ravil, Smith, Matt K., Dow, Pamela, Darakjian, Lucy I., Deodhar, Malavika, Cicali, Brian, Bain, Kevin T., Turgeon, Jacques
Publicado 2021