Vitamin in the Crosshairs: Targeting Pantothenate and Coenzyme A Biosynthesis for New Antituberculosis Agents

por Butman, Hailey S., Kotzé, Timothy J., Dowd, Cynthia S., Strauss, Erick
Publicado 2020

9-aminoacridine Inhibition of HIV-1 Tat Dependent Transcription

por Guendel, Irene, Carpio, Lawrence, Easley, Rebecca, Van Duyne, Rachel, Coley, William, Agbottah, Emmanuel, Dowd, Cynthia, Kashanchi, Fatah, Kehn-Hall, Kylene
Publicado 2009

Synthetic Fosmidomycin Analogues with Altered Chelating Moieties Do Not Inhibit 1-Deoxy-d-xylulose 5-phosphate Reductoisomerase or Plasmodium falciparum Growth In Vitro

por Chofor, René, Risseeuw, Martijn D.P., Pouyez, Jenny, Johny, Chinchu, Wouters, Johan, Dowd, Cynthia S., Couch, Robin D., Van Calenbergh, Serge
Publicado 2014

Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

por Wu, Weilin, Kehn-Hall, Kylene, Pedati, Caitlin, Zweier, Lynnsey, Castro, Iris, Klase, Zachary, Dowd, Cynthia S, Dubrovsky, Larisa, Bukrinsky, Michael, Kashanchi, Fatah
Publicado 2008

Mechanism of Action of N-Acyl and N-Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria

por Girma, Misgina B., Ball, Haley S., Wang, Xu, Brothers, Robert C., Jackson, Emily R., Meyers, Marvin J., Dowd, Cynthia S., Couch, Robin D.
Publicado 2021

Lipophilic Prodrugs of FR900098 Are Antimicrobial against Francisella novicida In Vivo and In Vitro and Show GlpT Independent Efficacy

por McKenney, Elizabeth S., Sargent, Michelle, Khan, Hameed, Uh, Eugene, Jackson, Emily R., Jose, Géraldine San, Couch, Robin D., Dowd, Cynthia S., van Hoek, Monique L.
Publicado 2012

Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase)

por Haymond, Amanda, Johny, Chinchu, Dowdy, Tyrone, Schweibenz, Brandon, Villarroel, Karen, Young, Richard, Mantooth, Clark J., Patel, Trishal, Bases, Jessica, Jose, Geraldine San, Jackson, Emily R., Dowd, Cynthia S., Couch, Robin D.
Publicado 2014

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

por Edwards, Rachel L., Brothers, Robert C., Wang, Xu, Maron, Maxim I., Ziniel, Peter D., Tsang, Patricia S., Kraft, Thomas E., Hruz, Paul W., Williamson, Kim C., Dowd, Cynthia S., John, Audrey R. Odom
Publicado 2017

Correction: Structure-guided microbial targeting of antistaphylococcal prodrugs

por Miller, Justin J, Shah, Ishaan T, Hatten, Jayda, Barekatain, Yasaman, Mueller, Elizabeth A, Moustafa, Ahmed M, Edwards, Rachel L, Dowd, Cynthia S, Hoops, Geoffrey C, Johnson, R Jeremy, Planet, Paul, Muller, Florian L, Jez, Joseph, Odom John, Audrey R
Publicado 2021

Structure-guided microbial targeting of antistaphylococcal prodrugs

por Miller, Justin J, Shah, Ishaan T, Hatten, Jayda, Barekatain, Yasaman, Mueller, Elizabeth A, Moustafa, Ahmed M, Edwards, Rachel L, Dowd, Cynthia S, Hoops, Geoffrey C, Johnson, R Jeremy, Planet, Paul J, Muller, Florian L, Jez, Joseph M, Odom John, Audrey R
Publicado 2021

Potent, specific MEPicides for treatment of zoonotic staphylococci

por Edwards, Rachel L., Heueck, Isabel, Lee, Soon Goo, Shah, Ishaan T., Miller, Justin J., Jezewski, Andrew J., Mikati, Marwa O., Wang, Xu, Brothers, Robert C., Heidel, Kenneth M., Osbourn, Damon M., Burnham, Carey-Ann D., Alvarez, Sophie, Fritz, Stephanie A., Dowd, Cynthia S., Jez, Joseph M., Odom John, Audrey R.
Publicado 2020