Structures of the alkanesulfonate monooxygenase MsuD provide insight into C–S bond cleavage, substrate scope, and an unexpected role for the tetramer

por Liew, Jeremy J.M., El Saudi, Israa M., Nguyen, Son V., Wicht, Denyce K., Dowling, Daniel P.
Publicado 2021

Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism

por Dowling, Daniel P., Bruender, Nathan A., Young, Anthony P., McCarty, Reid M., Bandarian, Vahe, Drennan, Catherine L.
Publicado 2013

Molecular basis of cobalamin-dependent RNA modification

por Dowling, Daniel P., Miles, Zachary D., Köhrer, Caroline, Maiocco, Stephanie J., Elliott, Sean J., Bandarian, Vahe, Drennan, Catherine L.
Publicado 2016

7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies

por Bruender, Nathan A., Grell, Tsehai A. J., Dowling, Daniel P., McCarty, Reid M., Drennan, Catherine L., Bandarian, Vahe
Publicado 2017

Global protein dynamics as communication sensors in peptide synthetase domains

por Mishra, Subrata H., Kancherla, Aswani K., Marincin, Kenneth A., Bouvignies, Guillaume, Nerli, Santrupti, Sgourakis, Nikolaos, Dowling, Daniel P., Frueh, Dominique P.
Publicado 2022

The NADH recycling enzymes TsaC and TsaD regenerate reducing equivalents for Rieske oxygenase chemistry

por Tian, Jiayi, Boggs, David G., Donnan, Patrick H., Barroso, Gage T., Garcia, Alejandro Arcadio, Dowling, Daniel P., Buss, Joshua A., Bridwell-Rabb, Jennifer
Publicado 2023

High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding

por Gnann, Andrew D., Xia, Yuan, Soule, Jess, Barthélemy, Clara, Mawani, Jayata S., Musoke, Sarah Nzikoba, Castellano, Brian M., Brignole, Edward J., Frueh, Dominique P., Dowling, Daniel P.
Publicado 2022

Pathways of thymidine hypermodification

por Lee, Yan-Jiun, Dai, Nan, Müller, Stephanie I, Guan, Chudi, Parker, Mackenzie J, Fraser, Morgan E, Walsh, Shannon E, Sridar, Janani, Mulholland, Andrew, Nayak, Krutika, Sun, Zhiyi, Lin, Yu-Cheng, Comb, Donald G, Marks, Katherine, Gonzalez, Reyaz, Dowling, Daniel P, Bandarian, Vahe, Saleh, Lana, Corrêa, Ivan R, Weigele, Peter R
Publicado 2021