Methylation of H3 K4 and K79 is not strictly dependent on H2B K123 ubiquitylation

por Foster, Elinor R., Downs, Jessica A.
Publicado 2009

Removal of H2A.Z by INO80 promotes homologous recombination

por Alatwi, Hanan E, Downs, Jessica A
Publicado 2015

The PBAF chromatin remodeling complex represses transcription and promotes rapid repair at DNA double-strand breaks

por Kakarougkas, Andreas, Downs, Jessica A, Jeggo, Penny A
Publicado 2015

A role for chromatin remodellers in replication of damaged DNA

por Niimi, Atsuko, Chambers, Anna L., Downs, Jessica A., Lehmann, Alan R.
Publicado 2012

The BAH domain of Rsc2 is a histone H3 binding domain

por Chambers, Anna L., Pearl, Laurence H., Oliver, Antony W., Downs, Jessica A.
Publicado 2013

BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy

por Brownlee, Peter M., Chambers, Anna L., Cloney, Ross, Bianchi, Alessandro, Downs, Jessica A.
Publicado 2014

Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers

por Benstead-Hume, Graeme, Wooller, Sarah K., Downs, Jessica A, Pearl, Frances M. G.
Publicado 2019

The Two Different Isoforms of the RSC Chromatin Remodeling Complex Play Distinct Roles in DNA Damage Responses

por Chambers, Anna L., Brownlee, Peter M., Durley, Samuel C., Beacham, Tracey, Kent, Nicholas A., Downs, Jessica A.
Publicado 2012

Predicting synthetic lethal interactions using conserved patterns in protein interaction networks

por Benstead-Hume, Graeme, Chen, Xiangrong, Hopkins, Suzanna R., Lane, Karen A., Downs, Jessica A., Pearl, Frances M. G.
Publicado 2019

PBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenance

por Feng, Hugang, Lane, Karen A., Roumeliotis, Theodoros I., Jeggo, Penny A., Somaiah, Navita, Choudhary, Jyoti S., Downs, Jessica A.
Publicado 2022

Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin

por Kakarougkas, Andreas, Ismail, Amani, Chambers, Anna L., Riballo, Enriqueta, Herbert, Alex D., Künzel, Julia, Löbrich, Markus, Jeggo, Penny A., Downs, Jessica A.
Publicado 2014

Aneuploidy tolerance caused by BRG1 loss allows chromosome gains and recovery of fitness

por Schiavoni, Federica, Zuazua-Villar, Pedro, Roumeliotis, Theodoros I., Benstead-Hume, Graeme, Pardo, Mercedes, Pearl, Frances M. G., Choudhary, Jyoti S., Downs, Jessica A.
Publicado 2022

Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1

por Pal, Mohinder, Morgan, Marc, Phelps, Sarah E.L., Roe, S. Mark, Parry-Morris, Sarah, Downs, Jessica A., Polier, Sigrun, Pearl, Laurence H., Prodromou, Chrisostomos
Publicado 2014

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

por Meisenberg, Cornelia, Pinder, Sarah I., Hopkins, Suzanna R., Wooller, Sarah K., Benstead-Hume, Graeme, Pearl, Frances M.G., Jeggo, Penny A., Downs, Jessica A.
Publicado 2019

TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells

por Anbalagan, Selvakumar, Ström, Cecilia, Downs, Jessica A., Jeggo, Penny A., McBay, David, Wilkins, Anna, Rothkamm, Kai, Harrington, Kevin J., Yarnold, John R., Somaiah, Navita
Publicado 2021

Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan

por Meisenberg, Cornelia, Ashour, Mohamed E., El-Shafie, Lamia, Liao, Chunyan, Hodgson, Adam, Pilborough, Alice, Khurram, Syed A., Downs, Jessica A., Ward, Simon E., El-Khamisy, Sherif F.
Publicado 2017

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

por Rother, Magdalena B., Pellegrino, Stefania, Smith, Rebecca, Gatti, Marco, Meisenberg, Cornelia, Wiegant, Wouter W., Luijsterburg, Martijn S., Imhof, Ralph, Downs, Jessica A., Vertegaal, Alfred C. O., Huet, Sébastien, Altmeyer, Matthias, van Attikum, Haico
Publicado 2020