The effect of increasing numbers of repeats on TAL effector DNA binding specificity

por Rinaldi, Fabio C., Doyle, Lindsey A., Stoddard, Barry L., Bogdanove, Adam J.
Publicado 2017

Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications

por Li, Hui, Ulge, Umut Y., Hovde, Blake T., Doyle, Lindsey A., Monnat, Raymond J.
Publicado 2012

Rational design of alpha-helical tandem repeat proteins with closed architectures

por Doyle, Lindsey, Hallinan, Jazmine, Bolduc, Jill, Parmeggiani, Fabio, Baker, David, Stoddard, Barry L., Bradley, Philip
Publicado 2015

The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1

por Grünberg, Sebastian, Doyle, Lindsey A., Wolf, Eric J., Dai, Nan, Corrêa, Ivan R., Yigit, Erbay, Stoddard, Barry L.
Publicado 2023

Sampling and energy evaluation challenges in ligand binding protein design

por Dou, Jiayi, Doyle, Lindsey, Jr. Greisen, Per, Schena, Alberto, Park, Hahnbeom, Johnsson, Kai, Stoddard, Barry L., Baker, David
Publicado 2017

Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI

por Shen, Betty W, Doyle, Lindsey, Bradley, Phil, Heiter, Daniel F, Lunnen, Keith D, Wilson, Geoffrey G, Stoddard, Barry L
Publicado 2019

A synthetic sex ratio distortion system for the control of the human malaria mosquito

por Galizi, Roberto, Doyle, Lindsey A., Menichelli, Miriam, Bernardini, Federica, Deredec, Anne, Burt, Austin, Stoddard, Barry L., Windbichler, Nikolai, Crisanti, Andrea
Publicado 2014

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display

por Jarjour, Jordan, West-Foyle, Hoku, Certo, Michael T., Hubert, Christopher G., Doyle, Lindsey, Getz, Melissa M., Stoddard, Barry L., Scharenberg, Andrew M.
Publicado 2009

De novo design of knotted tandem repeat proteins

por Doyle, Lindsey A., Takushi, Brittany, Kibler, Ryan D., Milles, Lukas F., Orozco, Carolina T., Jones, Jonathan D., Jackson, Sophie E., Stoddard, Barry L., Bradley, Philip
Publicado 2023

Precise assembly of complex beta sheet topologies from de novo designed building blocks

por King, Indigo Chris, Gleixner, James, Doyle, Lindsey, Kuzin, Alexandre, Hunt, John F, Xiao, Rong, Montelione, Gaetano T, Stoddard, Barry L, DiMaio, Frank, Baker, David
Publicado 2015

Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces

por Hallinan, Jazmine P., Doyle, Lindsey A., Shen, Betty W., Gewe, Mesfin M., Takushi, Brittany, Kennedy, Madison A., Friend, Della, Roberts, James M., Bradley, Philip, Stoddard, Barry L.
Publicado 2021

Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor

por Shen, Betty W, Doyle, Lindsey A, Werther, Rachel, Westburg, Abigail A, Bies, Daniel P, Walter, Stephanie I, Luyten, Yvette A, Morgan, Richard D, Stoddard, Barry L, Kaiser, Brett K
Publicado 2023

Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system

por Luyten, Yvette A, Hausman, Deanna E, Young, Juliana C, Doyle, Lindsey A, Higashi, Kerilyn M, Ubilla-Rodriguez, Natalia C, Lambert, Abigail R, Arroyo, Corina S, Forsberg, Kevin J, Morgan, Richard D, Stoddard, Barry L, Kaiser, Brett K
Publicado 2022

De novo design of a fluorescence-activating β-barrel

por Dou, Jiayi, Vorobieva, Anastassia A., Sheffler, William, Doyle, Lindsey A., Park, Hahnbeom, Bick, Matthew J., Mao, Binchen, Foight, Glenna W., Lee, Min Yen, Gagnon, Lauren A., Carter, Lauren, Sankaran, Banumathi, Ovchinnikov, Sergey, Marcos, Enrique, Huang, Po-Ssu, Vaughan, Joshua C., Stoddard, Barry L., Baker, David
Publicado 2018

Computational design of sequence-specific DNA-binding proteins

por Glasscock, Cameron J., Pecoraro, Robert, McHugh, Ryan, Doyle, Lindsey A., Chen, Wei, Boivin, Olivier, Lonnquist, Beau, Na, Emily, Politanska, Yuliya, Haddox, Hugh K., Cox, David, Norn, Christoffer, Coventry, Brian, Goreshnik, Inna, Vafeados, Dionne, Lee, Gyu Rie, Gordan, Raluca, Stoddard, Barry L., DiMaio, Frank, Baker, David
Publicado 2023

Incorporation of sensing modalities into de novo designed fluorescence-activating proteins

por Klima, Jason C., Doyle, Lindsey A., Lee, Justin Daho, Rappleye, Michael, Gagnon, Lauren A., Lee, Min Yen, Barros, Emilia P., Vorobieva, Anastassia A., Dou, Jiayi, Bremner, Samantha, Quon, Jacob S., Chow, Cameron M., Carter, Lauren, Mack, David L., Amaro, Rommie E., Vaughan, Joshua C., Berndt, Andre, Stoddard, Barry L., Baker, David
Publicado 2021