Metabolic reprogramming: a bridge between aging and tumorigenesis

por Drapela, Stanislav, Ilter, Didem, Gomes, Ana P.
Publicado 2022

ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance

por Drápela, Stanislav, Bouchal, Jan, Jolly, Mohit Kumar, Culig, Zoran, Souček, Karel
Publicado 2020

Circulating tumor cell-derived preclinical models: current status and future perspectives

por Kahounová, Zuzana, Pícková, Markéta, Drápela, Stanislav, Bouchal, Jan, Szczyrbová, Eva, Navrátil, Jiří, Souček, Karel
Publicado 2023

The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel‐resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe

por Drápela, Stanislav, Khirsariya, Prashant, van Weerden, Wytske M., Fedr, Radek, Suchánková, Tereza, Búzová, Diana, Červený, Jan, Hampl, Aleš, Puhr, Martin, Watson, William R., Culig, Zoran, Krejčí, Lumír, Paruch, Kamil, Souček, Karel
Publicado 2020

NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis

por Ilter, Didem, Drapela, Stanislav, Schild, Tanya, Ward, Nathan P., Adhikari, Emma, Low, Vivien, Asara, John, Oskarsson, Thordur, Lau, Eric K., DeNicola, Gina M., McReynolds, Melanie R., Gomes, Ana P.
Publicado 2023

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells

por Boudny, Miroslav, Zemanova, Jana, Khirsariya, Prashant, Borsky, Marek, Verner, Jan, Cerna, Jana, Oltova, Alexandra, Seda, Vaclav, Mraz, Marek, Jaros, Josef, Jaskova, Zuzana, Spunarova, Michaela, Brychtova, Yvona, Soucek, Karel, Drapela, Stanislav, Kasparkova, Marie, Mayer, Jiri, Paruch, Kamil, Trbusek, Martin
Publicado 2019

Altered propionate metabolism contributes to tumor progression and aggressiveness

por Gomes, Ana P., Ilter, Didem, Low, Vivien, Drapela, Stanislav, Schild, Tanya, Mullarky, Edouard, Han, Julie, Elia, Ilaria, Broekaert, Dorien, Rosenzweig, Adam, Nagiec, Michal, Nunes, Joana B., Schaffer, Bethany E., Mutvei, Anders P., Asara, John M., Cantley, Lewis C., Fendt, Sarah-Maria, Blenis, John
Publicado 2022