Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells

por Drabek, Dubravka, Janssens, Rick, de Boer, Ernie, Rademaker, Rik, Kloess, Johannes, Skehel, John, Grosveld, Frank
Publicado 2016

A Dual Reporter Mouse Model of the Human β-Globin Locus: Applications and Limitations

por Papadopoulos, Petros, Gutiérrez, Laura, van der Linden, Reinier, Kong-A-San, John, Maas, Alex, Drabek, Dubravka, Patrinos, George P., Philipsen, Sjaak, Grosveld, Frank
Publicado 2012

A human monoclonal antibody blocking SARS-CoV-2 infection

por Wang, Chunyan, Li, Wentao, Drabek, Dubravka, Okba, Nisreen M. A., van Haperen, Rien, Osterhaus, Albert D. M. E., van Kuppeveld, Frank J. M., Haagmans, Bart L., Grosveld, Frank, Bosch, Berend-Jan
Publicado 2020

Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection

por Wang, Chunyan, Li, Wentao, Drabek, Dubravka, Okba, Nisreen M. A., van Haperen, Rien, Osterhaus, Albert D. M. E., van Kuppeveld, Frank J. M., Haagmans, Bart L., Grosveld, Frank, Bosch, Berend-Jan
Publicado 2020

WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion

por Lehmann, Johannes, Narcisi, Roberto, Franceschini, Natasja, Chatzivasileiou, Danai, Boer, Cindy G., Koevoet, Wendy J. L. M., Putavet, Diana, Drabek, Dubravka, van Haperen, Rien, de Keizer, Peter L. J., van Osch, Gerjo J. V. M., ten Berge, Derk
Publicado 2022

An anti-CTLA-4 heavy chain–only antibody with enhanced T(reg) depletion shows excellent preclinical efficacy and safety profile

por Gan, Xin, Shan, Qianqian, Li, He, Janssens, Rick, Shen, Yuqiang, He, Yun, Chen, Fei, van Haperen, Rien, Drabek, Dubravka, Li, Jin, Zhang, Yang, Zhao, Jiuqiao, Qin, Beibei, Jheng, Ming-Jin, Chen, Victor, Wang, Jingsong, Rong, Yiping, Grosveld, Frank
Publicado 2022

Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein

por Widjaja, Ivy, Wang, Chunyan, van Haperen, Rien, Gutiérrez-Álvarez, Javier, van Dieren, Brenda, Okba, Nisreen M.A., Raj, V. Stalin, Li, Wentao, Fernandez-Delgado, Raul, Grosveld, Frank, van Kuppeveld, Frank J. M., Haagmans, Bart L., Enjuanes, Luis, Drabek, Dubravka, Bosch, Berend-Jan
Publicado 2019

Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes

por Wang, Chunyan, Hesketh, Emma L., Shamorkina, Tatiana M., Li, Wentao, Franken, Peter J., Drabek, Dubravka, van Haperen, Rien, Townend, Sarah, van Kuppeveld, Frank J. M., Grosveld, Frank, Ranson, Neil A., Snijder, Joost, de Groot, Raoul J., Hurdiss, Daniel L., Bosch, Berend-Jan
Publicado 2022

Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants

por Du, Wenjuan, Janssens, Rick, Mykytyn, Anna Z., Li, Wentao, Drabek, Dubravka, van Haperen, Rien, Chatziandreou, Marianthi, Rissmann, Melanie, van der Lee, Joline, van Dortmondt, Melissa, Martin, Itziar Serna, van Kuppeveld, Frank J. M., Hurdiss, Daniel L., Haagmans, Bart L., Grosveld, Frank, Bosch, Berend-Jan
Publicado 2023

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

por Stalin Raj, V., Okba, Nisreen M. A., Gutierrez-Alvarez, Javier, Drabek, Dubravka, van Dieren, Brenda, Widagdo, W., Lamers, Mart M., Widjaja, Ivy, Fernandez-Delgado, Raul, Sola, Isabel, Bensaid, Albert, Koopmans, Marion P., Segalés, Joaquim, Osterhaus, Albert D. M. E., Bosch, Berend Jan, Enjuanes, Luis, Haagmans, Bart L.
Publicado 2018

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

por Wang, Chunyan, van Haperen, Rien, Gutiérrez-Álvarez, Javier, Li, Wentao, Okba, Nisreen M. A., Albulescu, Irina, Widjaja, Ivy, van Dieren, Brenda, Fernandez-Delgado, Raul, Sola, Isabel, Hurdiss, Daniel L., Daramola, Olalekan, Grosveld, Frank, van Kuppeveld, Frank J. M., Haagmans, Bart L., Enjuanes, Luis, Drabek, Dubravka, Bosch, Berend-Jan
Publicado 2021

Multimeric single-domain antibody complexes protect against bunyavirus infections

por Wichgers Schreur, Paul J, van de Water, Sandra, Harmsen, Michiel, Bermúdez-Méndez, Erick, Drabek, Dubravka, Grosveld, Frank, Wernike, Kerstin, Beer, Martin, Aebischer, Andrea, Daramola, Olalekan, Rodriguez Conde, Sara, Brennan, Karen, Kozub, Dorota, Søndergaard Kristiansen, Maiken, Mistry, Kieran K, Deng, Ziyan, Hellert, Jan, Guardado-Calvo, Pablo, Rey, Félix A, van Keulen, Lucien, Kortekaas, Jeroen
Publicado 2020

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern

por Du, Wenjuan, Hurdiss, Daniel L., Drabek, Dubravka, Mykytyn, Anna Z., Kaiser, Franziska K., González-Hernández, Mariana, Muñoz-Santos, Diego, Lamers, Mart M., van Haperen, Rien, Li, Wentao, Drulyte, Ieva, Wang, Chunyan, Sola, Isabel, Armando, Federico, Beythien, Georg, Ciurkiewicz, Malgorzata, Baumgärtner, Wolfgang, Guilfoyle, Kate, Smits, Tony, van der Lee, Joline, van Kuppeveld, Frank J.M., van Amerongen, Geert, Haagmans, Bart L., Enjuanes, Luis, Osterhaus, Albert D.M.E., Grosveld, Frank, Bosch, Berend-Jan
Publicado 2022