Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research

por Inoue, Akira, Deem, Angela K., Kopetz, Scott, Heffernan, Timothy P., Draetta, Giulio F., Carugo, Alessandro
Publicado 2019

Genetics and biology of pancreatic ductal adenocarcinoma

por Ying, Haoqiang, Dey, Prasenjit, Yao, Wantong, Kimmelman, Alec C., Draetta, Giulio F., Maitra, Anirban, DePinho, Ronald A.
Publicado 2016

Targeting mitochondrial respiration and the BCL2 family in high‐grade MYC‐associated B‐cell lymphoma

por Donati, Giulio, Ravà, Micol, Filipuzzi, Marco, Nicoli, Paola, Cassina, Laura, Verrecchia, Alessandro, Doni, Mirko, Rodighiero, Simona, Parodi, Federica, Boletta, Alessandra, Vellano, Christopher P., Marszalek, Joseph R., Draetta, Giulio F., Amati, Bruno
Publicado 2021

Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAF(V600E) inhibition resistance in melanoma

por Zhang, Ze-Yan, Ding, Yingwen, Ezhilarasan, Ravesanker, Lhakhang, Tenzin, Wang, Qianghu, Yang, Jie, Modrek, Aram S., Zhang, Hua, Tsirigos, Aristotelis, Futreal, Andrew, Draetta, Giulio F., Verhaak, Roel G. W., Sulman, Erik P.
Publicado 2022

Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways

por Invrea, Federica, Punzi, Simona, Petti, Consalvo, Minelli, Rosalba, Peoples, Michael D., Bristow, Christopher A., Vurchio, Valentina, Corrado, Alessia, Bragoni, Alberto, Marchiò, Caterina, Bertotti, Andrea, Trusolino, Livio, Bardelli, Alberto, Isella, Claudio, Carugo, Alessandro, Draetta, Giulio F., Medico, Enzo
Publicado 2021

Immune landscape of a genetically engineered murine model of glioma compared with human glioma

por Zamler, Daniel B., Shingu, Takashi, Kahn, Laura M., Huntoon, Kristin, Kassab, Cynthia, Ott, Martina, Tomczak, Katarzyna, Liu, Jintan, Li, Yating, Lai, Ivy, Zorilla-Veloz, Rocio, Yee, Cassian, Rai, Kunal, Kim, Betty Y.S., Watowich, Stephanie S., Heimberger, Amy B., Draetta, Giulio F., Hu, Jian
Publicado 2022

miR‐9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC

por Citron, Francesca, Segatto, Ilenia, Musco, Lorena, Pellarin, Ilenia, Rampioni Vinciguerra, Gian Luca, Franchin, Giovanni, Fanetti, Giuseppe, Miccichè, Francesco, Giacomarra, Vittorio, Lupato, Valentina, Favero, Andrea, Concina, Isabella, Srinivasan, Sanjana, Avanzo, Michele, Castiglioni, Isabella, Barzan, Luigi, Sulfaro, Sandro, Petrone, Gianluigi, Viale, Andrea, Draetta, Giulio F, Vecchione, Andrea, Belletti, Barbara, Baldassarre, Gustavo
Publicado 2021

Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis

por Chen, Ziheng, Ho, I-Lin, Soeung, Melinda, Yen, Er-Yen, Liu, Jintan, Yan, Liang, Rose, Johnathon L., Srinivasan, Sanjana, Jiang, Shan, Edward Chang, Q., Feng, Ningping, Gay, Jason P., Wang, Qi, Wang, Jing, Lorenzi, Philip L., Veillon, Lucas J., Wei, Bo, Weinstein, John N., Deem, Angela K., Gao, Sisi, Genovese, Giannicola, Viale, Andrea, Yao, Wantong, Lyssiotis, Costas A., Marszalek, Joseph R., Draetta, Giulio F., Ying, Haoqiang
Publicado 2023

SMARCB1 regulates the hypoxic stress response in sickle cell trait

por Soeung, Melinda, Perelli, Luigi, Chen, Ziheng, Dondossola, Eleonora, Ho, I-Lin, Carbone, Federica, Zhang, Li, Khan, Hania, Le, Courtney N., Zhu, Cihui, Peoples, Michael D., Feng, Ningping, Jiang, Shan, Zacharias, Niki Millward, Minelli, Rosalba, Shapiro, Daniel D., Deem, Angela K., Gao, Sisi, Cheng, Emily H., Lucchetti, Donatella, Walker, Cheryl L., Carugo, Alessandro, Giuliani, Virginia, Heffernan, Timothy P., Viale, Andrea, Tannir, Nizar M., Draetta, Giulio F., Msaouel, Pavlos, Genovese, Giannicola
Publicado 2023

Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer

por Evans, Kurt W., Yuca, Erkan, Scott, Stephen S., Zhao, Ming, Paez Arango, Natalia, Cruz Pico, Christian X., Saridogan, Turcin, Shariati, Maryam, Class, Caleb A., Bristow, Christopher A., Vellano, Christopher P., Zheng, Xiaofeng, Gonzalez-Angulo, Ana Maria, Su, Xiaoping, Tapia, Coya, Chen, Ken, Akcakanat, Argun, Lim, Bora, Tripathy, Debu, Yap, Timothy A., Francesco, Maria Emilia Di, Draetta, Giulio F., Jones, Philip, Heffernan, Timothy P., Marszalek, Joseph R., Meric-Bernstam, Funda
Publicado 2021

Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies

por Shapiro, Daniel D., Soeung, Melinda, Perelli, Luigi, Dondossola, Eleonora, Surasi, Devaki Shilpa, Tripathi, Durga N., Bertocchio, Jean-Philippe, Carbone, Federica, Starbuck, Michael W., Van Alstine, Michael L., Rao, Priya, Katz, Matthew H. G., Parker, Nathan H., Shah, Amishi Y., Carugo, Alessandro, Heffernan, Timothy P., Schadler, Keri L., Logothetis, Christopher, Walker, Cheryl L., Wood, Christopher G., Karam, Jose A., Draetta, Giulio F., Tannir, Nizar M., Genovese, Giannicola, Msaouel, Pavlos
Publicado 2021

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

por Puca, Francesca, Yu, Fei, Bartolacci, Caterina, Pettazzoni, Piergiorgio, Carugo, Alessandro, Huang-Hobbs, Emmet, Liu, Jintan, Zanca, Ciro, Carbone, Federica, Del Poggetto, Edoardo, Gumin, Joy, Dasgupta, Pushan, Seth, Sahil, Srinivasan, Sanjana, Lang, Frederick F., Sulman, Erik P., Lorenzi, Philip L., Tan, Lin, Shan, Mengrou, Tolstyka, Zachary P., Kachman, Maureen, Zhang, Li, Gao, Sisi, Deem, Angela K., Genovese, Giannicola, Scaglioni, Pier Paolo, Lyssiotis, Costas A., Viale, Andrea, Draetta, Giulio F.
Publicado 2021

Syndecan1 is a critical mediator of macropinocytosis in pancreatic cancer

por Yao, Wantong, Rose, Johnathon L., Wang, Wei, Seth, Sahil, Jiang, Hong, Taguchi, Ayumu, Liu, Jintan, Yan, Liang, Kapoor, Avnish, Hou, Pingping, Chen, Ziheng, Wang, Qiuyun, Nezi, Luigi, Xu, Zhaohui, Yao, Jun, Hu, Baoli, Pettazzoni, Piergiorgio F., Ho, I Lin, Feng, Ningping, Ramamoorthy, Vandhana, Jiang, Shan, Deng, Pingna, Ma, Grace J., Den, Peter, Tan, Zhi, Zhang, Shu Xing, Wang, Huamin, Wang, Alan Y., Deem, Angela K., Fleming, Jason B., Carugo, Alessandro, Heffernan, Timothy P., Maitra, Anirban, Viale, Andrea, Ying, Haoqiang, Hanash, Samir, DePinho, Ronald A., Draetta, Giulio F.
Publicado 2019

Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer

por Perelli, Luigi, Carbone, Federica, Zhang, Li, Huang, Justin K., Le, Courtney, Khan, Hania, Citron, Francesca, Del Poggetto, Edoardo, Gutschner, Tony, Tomihara, Hideo, Soeung, Melinda, Minelli, Rosalba, Srinivasan, Sanjana, Peoples, Michael, Lam, Truong Nguyen Anh, Lundgren, Sebastian, Xia, Ruohan, Zhu, Cihui, Mohamed, Alaa M. T., Zhang, Jianhua, Sircar, Kanishka, Sgambato, Alessandro, Gao, JianJun, Jonasch, Eric, Draetta, Giulio F., Futreal, Andrew, Bakouny, Ziad, Van Allen, Eliezer M., Choueiri, Toni, Signoretti, Sabina, Msaouel, Pavlos, Litchfield, Kevin, Turajlic, Samra, Wang, Linghua, Chen, Ying Bei, Di Natale, Renzo G., Hakimi, A. Ari, Giuliani, Virginia, Heffernan, Timothy P., Viale, Andrea, Bristow, Christopher A., Tannir, Nizar M., Carugo, Alessandro, Genovese, Giannicola
Publicado 2023