Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions

por Chaturvedi, Sumit K., Parupudi, Arun, Juul-Madsen, Kristian, Nguyen, Ai, Vorup-Jensen, Thomas, Dragulin-Otto, Sonia, Zhao, Huaying, Esfandiary, Reza, Schuck, Peter
Publicado 2020

Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations

por Parupudi, Arun, Chaturvedi, Sumit K., Adão, Regina, Harkness, Robert W., Dragulin-Otto, Sonia, Kay, Lewis E., Esfandiary, Reza, Zhao, Huaying, Schuck, Peter
Publicado 2021

In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

por Shan, Lu, Dyk, Nydia Van, Haskins, Nantaporn, Cook, Kimberly M., Rosenthal, Kim L., Mazor, Ronit, Dragulin-Otto, Sonia, Jiang, Yu, Wu, Herren, Dall’Acqua, William F., Borrok, Martin J., Damschroder, Melissa M., Oganesyan, Vaheh
Publicado 2021