Targeting healthspan to optimally combat non-communicable disease in an aging world

por Drake, Joshua C., Yan, Zhen
Publicado 2019

Normalizing a hyperactive mTOR initiates muscle growth during obesity

por Williamson, David L., Drake, Joshua C.
Publicado 2011

Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog

por Bandara, Aloka B., Drake, Joshua C., Brown, David A.
Publicado 2021

Sensing local energetics to acutely regulate mitophagy in skeletal muscle

por Nichenko, Anna S., Specht, Kalyn S., Craige, Siobhan M., Drake, Joshua C.
Publicado 2022

Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle

por Drake, Joshua C., Wilson, Rebecca J., Cui, Di, Guan, Yuntian, Kundu, Mondira, Zhang, Mei, Yan, Zhen
Publicado 2021

Long-term voluntary running prevents the onset of symptomatic Friedreich’s ataxia in mice

por Zhao, Henan, Lewellen, Bevan M., Wilson, Rebecca J., Cui, Di, Drake, Joshua C., Zhang, Mei, Yan, Zhen
Publicado 2020

Author Correction: Long-term voluntary running prevents the onset of symptomatic Friedreich’s ataxia in mice

por Zhao, Henan, Lewellen, Bevan M., Wilson, Rebecca J., Cui, Di, Drake, Joshua C., Zhang, Mei, Yan, Zhen
Publicado 2021

Nrf2 Signaling and the Slowed Aging Phenotype: Evidence from Long-Lived Models

por Bruns, Danielle R., Drake, Joshua C., Biela, Laurie M., Peelor, Frederick F., Miller, Benjamin F., Hamilton, Karyn L.
Publicado 2015

Mitochondrial plasticity supports proliferative outgrowth and invasion of ovarian cancer spheroids during adhesion

por Grieco, Joseph P., Compton, Stephanie L. E., Bano, Nazia, Brookover, Lucy, Nichenko, Anna S., Drake, Joshua C., Schmelz, Eva M.
Publicado 2023

Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity

por Drake, Joshua C, Bruns, Danielle R, Peelor, Frederick F, Biela, Laurie M, Miller, Richard A, Miller, Benjamin F, Hamilton, Karyn L
Publicado 2015

Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle

por Wilson, Rebecca J., Drake, Joshua C., Cui, Di, Lewellen, Bevan M., Fisher, Carleigh C., Zhang, Mei, Kashatus, David F., Palmer, Lisa A., Murphy, Michael P., Yan, Zhen
Publicado 2018

Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy

por Wilson, Rebecca J., Drake, Joshua C., Cui, Di, Zhang, Mei, Perry, Heather M., Kashatus, Jennifer A., Kusminski, Christine M., Scherer, Philipp E., Kashatus, David F., Okusa, Mark D., Yan, Zhen
Publicado 2017

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

por Laker, Rhianna C., Drake, Joshua C., Wilson, Rebecca J., Lira, Vitor A., Lewellen, Bevan M., Ryall, Karen A., Fisher, Carleigh C., Zhang, Mei, Saucerman, Jeffrey J., Goodyear, Laurie J., Kundu, Mondira, Yan, Zhen
Publicado 2017

AMPK-mediated potentiation of GABAergic signalling drives hypoglycaemia-provoked spike-wave seizures

por Salvati, Kathryn A, Ritger, Matthew L, Davoudian, Pasha A, O’Dell, Finnegan, Wyskiel, Daniel R, Souza, George M P R, Lu, Adam C, Perez-Reyes, Edward, Drake, Joshua C, Yan, Zhen, Beenhakker, Mark P
Publicado 2022

Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy

por Drake, Joshua C., Wilson, Rebecca J., Laker, Rhianna C., Guan, Yuntian, Spaulding, Hannah R., Nichenko, Anna S., Shen, Wenqing, Shang, Huayu, Dorn, Maya V., Huang, Kian, Zhang, Mei, Bandara, Aloka B., Brisendine, Matthew H., Kashatus, Jennifer A., Sharma, Poonam R., Young, Alexander, Gautam, Jitendra, Cao, Ruofan, Wallrabe, Horst, Chang, Paul A., Wong, Michael, Desjardins, Eric M., Hawley, Simon A., Christ, George J., Kashatus, David F., Miller, Clint L., Wolf, Matthew J., Periasamy, Ammasi, Steinberg, Gregory R., Hardie, D. Grahame, Yan, Zhen
Publicado 2021