Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products

por Sullivan, Amy H., Dranow, David M., Horanyi, Peter S., Lorimer, Donald D., Edwards, Thomas E., Abendroth, Jan
Publicado 2019

Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum

por Brooks, Lauryn, Subramanian, Sandhya, Dranow, David M., Mayclin, Stephen J., Myler, Peter J., Asojo, Oluwatoyin A.
Publicado 2022

Crystal structure of betaine aldehyde dehydrogenase from Burkholderia pseudomallei

por Beard, Dylan K., Subramanian, Sandhya, Abendroth, Jan, Dranow, David M., Edwards, Thomas E., Myler, Peter J., Asojo, Oluwatoyin A.
Publicado 2022

Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module

por Schirmer, Tilman, de Beer, Tjaart A. P., Tamegger, Stefanie, Harms, Alexander, Dietz, Nikolaus, Dranow, David M., Edwards, Thomas E., Myler, Peter J., Phan, Isabelle, Dehio, Christoph
Publicado 2021

Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody

por Xie, Bin, Maker, Allison, Priest, Andrew V., Dranow, David M., Phan, Jenny N., Edwards, Thomas E., Staker, Bart L., Myler, Peter J., Gumbiner, Barry M., Sivasankar, Sanjeevi
Publicado 2022

Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

por Moen, Spencer O., Edwards, Thomas E., Dranow, David M., Clifton, Matthew C., Sankaran, Banumathi, Van Voorhis, Wesley C., Sharma, Amit, Manoil, Colin, Staker, Bart L., Myler, Peter J., Lorimer, Donald D.
Publicado 2017

Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1

por Ghafoori, Seyed Mohammad, Robles, Alyssa M., Arada, Angelika M., Shirmast, Paniz, Dranow, David M., Mayclin, Stephen J., Lorimer, Donald D., Myler, Peter J., Edwards, Thomas E., Kuhn, Misty L., Forwood, Jade K.
Publicado 2021

Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis

por Porter, Imani, Neal, Trinity, Walker, Zion, Hayes, Dylan, Fowler, Kayla, Billups, Nyah, Rhoades, Anais, Smith, Christian, Smith, Kaelyn, Staker, Bart L., Dranow, David M., Mayclin, Stephen J., Subramanian, Sandhya, Edwards, Thomas E., Myler, Peter J., Asojo, Oluwatoyin A.
Publicado 2022

Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

por Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2016

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

por Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2016

A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1

por Clifton, Matthew C., Dranow, David M., Leed, Alison, Fulroth, Ben, Fairman, James W., Abendroth, Jan, Atkins, Kateri A., Wallace, Ellen, Fan, Dazhong, Xu, Guoping, Ni, Z. J., Daniels, Doug, Van Drie, John, Wei, Guo, Burgin, Alex B., Golub, Todd R., Hubbard, Brian K., Serrano-Wu, Michael H.
Publicado 2015

Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome

por Baugh, Loren, Gallagher, Larry A., Patrapuvich, Rapatbhorn, Clifton, Matthew C., Gardberg, Anna S., Edwards, Thomas E., Armour, Brianna, Begley, Darren W., Dieterich, Shellie H., Dranow, David M., Abendroth, Jan, Fairman, James W., Fox, David, Staker, Bart L., Phan, Isabelle, Gillespie, Angela, Choi, Ryan, Nakazawa-Hewitt, Steve, Nguyen, Mary Trang, Napuli, Alberto, Barrett, Lynn, Buchko, Garry W., Stacy, Robin, Myler, Peter J., Stewart, Lance J., Manoil, Colin, Van Voorhis, Wesley C.
Publicado 2013

Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase

por Hewitt, Stephen Nakazawa, Dranow, David M., Horst, Benjamin G., Abendroth, Jan A., Forte, Barbara, Hallyburton, Irene, Jansen, Chimed, Baragaña, Beatriz, Choi, Ryan, Rivas, Kasey L., Hulverson, Matthew A., Dumais, Mitchell, Edwards, Thomas E., Lorimer, Donald D., Fairlamb, Alan H., Gray, David W., Read, Kevin D., Lehane, Adele M., Kirk, Kiaran, Myler, Peter J., Wernimont, Amy, Walpole, Chris, Stacy, Robin, Barrett, Lynn K., Gilbert, Ian H., Van Voorhis, Wesley C.
Publicado 2016

Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major

por Iwasaki, Jua, Lorimer, Donald D., Vivoli-Vega, Mirella, Kibble, Emily A., Peacock, Christopher S., Abendroth, Jan, Mayclin, Stephen J., Dranow, David M., Pierce, Phillip G., Fox, David, Lewis, Maria, Bzdyl, Nicole M., Kristensen, Sofie S., Inglis, Timothy J. J., Kahler, Charlene M., Bond, Charles S., Hasenkopf, Anja, Seufert, Florian, Schmitz, Jens, Marshall, Laura E., Scott, Andrew E., Norville, Isobel H., Myler, Peter J., Holzgrabe, Ulrike, Harmer, Nicholas J., Sarkar-Tyson, Mitali
Publicado 2022

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

por Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W., Osterhout, Bram, Tran, Nathan L., Xu, Lily, Young, Ryan M., Craig, Justin, Chun, Ian, Dranow, David M., Abendroth, Jan, Delker, Silvia L., Davies, Douglas R., Mayclin, Stephen J., Calhoun, Brandy, Bolejack, Madison J., Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D., Myler, Peter J., Edwards, Thomas E., Kyle, Dennis E., Rice, Christopher A., Morris, James C., Leahy, James W., Manetsch, Roman, Barrett, Lynn K., Smith, Craig L., Van Voorhis, Wesley C.
Publicado 2021

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

por Baragaña, Beatriz, Forte, Barbara, Choi, Ryan, Nakazawa Hewitt, Stephen, Bueren-Calabuig, Juan A., Pisco, João Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O’Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.
Publicado 2019