A cell-based simulation software for multi-cellular systems

por Hoehme, Stefan, Drasdo, Dirk
Publicado 2010

Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance

por Bertaux, François, Stoma, Szymon, Drasdo, Dirk, Batt, Gregory
Publicado 2014

Guided interactive image segmentation using machine learning and color-based image set clustering

por Friebel, Adrian, Johann, Tim, Drasdo, Dirk, Hoehme, Stefan
Publicado 2022

Individual fates of mesenchymal stem cells in vitro

por Krinner, Axel, Hoffmann, Martin, Loeffler, Markus, Drasdo, Dirk, Galle, Joerg
Publicado 2010

Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data

por Jagiella, Nick, Müller, Benedikt, Müller, Margareta, Vignon-Clementel, Irene E., Drasdo, Dirk
Publicado 2016

Estimating Dose Painting Effects in Radiotherapy: A Mathematical Model

por López Alfonso, Juan Carlos, Jagiella, Nick, Núñez, Luis, Herrero, Miguel A., Drasdo, Dirk
Publicado 2014

Quantitative cell-based model predicts mechanical stress response of growing tumor spheroids over various growth conditions and cell lines

por Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Alessandri, Kevin, Nassoy, Pierre, Drasdo, Dirk
Publicado 2019

Quantitative modeling identifies critical cell mechanics driving bile duct lumen formation

por Van Liedekerke, Paul, Gannoun, Lila, Loriot, Axelle, Johann, Tim, Lemaigre, Frédéric P., Drasdo, Dirk
Publicado 2022

A proof-of-concept pipeline to guide evaluation of tumor tissue perfusion by dynamic contrast-agent imaging: Direct simulation and inverse tracer-kinetic procedures

por Vignon-Clementel, Irene E., Jagiella, Nick, Dichamp, Jules, Kowalski, Jérôme, Lederle, Wiltrud, Laue, Hendrik, Kiessling, Fabian, Sedlaczek, Oliver, Drasdo, Dirk
Publicado 2023

A quantitative high-resolution computational mechanics cell model for growing and regenerating tissues

por Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Warmt, Enrico, Gonzàlez-Valverde, Ismael, Hoehme, Stefan, Grosser, Steffen, Kaes, Josef, Drasdo, Dirk
Publicado 2019

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy

por Hoehme, Stefan, Hammad, Seddik, Boettger, Jan, Begher-Tibbe, Brigitte, Bucur, Petru, Vibert, Eric, Gebhardt, Rolf, Hengstler, Jan G., Drasdo, Dirk
Publicado 2022

In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin

por Dichamp, Jules, Cellière, Geraldine, Ghallab, Ahmed, Hassan, Reham, Boissier, Noemie, Hofmann, Ute, Reinders, Joerg, Sezgin, Selahaddin, Zühlke, Sebastian, Hengstler, Jan G., Drasdo, Dirk
Publicado 2023

Enabling multiscale modeling in systems medicine

por Wolkenhauer, Olaf, Auffray, Charles, Brass, Olivier, Clairambault, Jean, Deutsch, Andreas, Drasdo, Dirk, Gervasio, Francesco, Preziosi, Luigi, Maini, Philip, Marciniak-Czochra, Anna, Kossow, Christina, Kuepfer, Lars, Rateitschak, Katja, Ramis-Conde, Ignacio, Ribba, Benjamin, Schuppert, Andreas, Smallwood, Rod, Stamatakos, Georgios, Winter, Felix, Byrne, Helen
Publicado 2014

Influence of Liver Fibrosis on Lobular Zonation

por Ghallab, Ahmed, Myllys, Maiju, H. Holland, Christian, Zaza, Ayham, Murad, Walaa, Hassan, Reham, A. Ahmed, Yasser, Abbas, Tahany, A. Abdelrahim, Eman, Schneider, Kai Markus, Matz-Soja, Madlen, Reinders, Jörg, Gebhardt, Rolf, Berres, Marie-Luise, Hatting, Maximilian, Drasdo, Dirk, Saez-Rodriguez, Julio, Trautwein, Christian, G. Hengstler, Jan
Publicado 2019

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

por Ghallab, Ahmed, Hofmann, Ute, Sezgin, Selahaddin, Vartak, Nachiket, Hassan, Reham, Zaza, Ayham, Godoy, Patricio, Schneider, Kai Markus, Guenther, Georgia, Ahmed, Yasser A., Abbas, Aya A., Keitel, Verena, Kuepfer, Lars, Dooley, Steven, Lammert, Frank, Trautwein, Christian, Spiteller, Michael, Drasdo, Dirk, Hofmann, Alan F., Jansen, Peter L.M., Hengstler, Jan G., Reif, Raymond
Publicado 2018

Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture b...

por Hammad, Seddik, Hoehme, Stefan, Friebel, Adrian, von Recklinghausen, Iris, Othman, Amnah, Begher-Tibbe, Brigitte, Reif, Raymond, Godoy, Patricio, Johann, Tim, Vartak, Amruta, Golka, Klaus, Bucur, Petru O., Vibert, Eric, Marchan, Rosemarie, Christ, Bruno, Dooley, Steven, Meyer, Christoph, Ilkavets, Iryna, Dahmen, Uta, Dirsch, Olaf, Böttger, Jan, Gebhardt, Rolf, Drasdo, Dirk, Hengstler, Jan G.
Publicado 2014

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado 2013